Put on a pair of thick work gloves and wear long sleeves so you don't get bitten or scratched. Ask the vet prescribing the Drontal for a little plastic syringe called a pill gun. You can open her mouth and just shoot the pill straight down her throat with the syringe, it's very easy, it's how I administer pills to my cats. Or you could try to smash the pill up and put it in some tuna or other food, but in my experience, the pill must have a bitter taste because that method has never worked for me and cats have not eaten the food with the Drontal. If you're going to place the pill directly in her mouth, take special care not to get bitten. Even docile domesticated cats can panic and bite. Also, if you are near a PetSmart or some type of store like that, you might want to get some Feliway spray. I have a small bottle that has lasted me for years. It is a calming pheromone based thing that I spray my pet carrier with when having to take a cat to the vet. There are Feliway plugins, but I think they are more expensive, the spray doesn't cost that much and lasts for a long time. You could spray the box she is using, or some other object she is near when she is in the room. Hang in there.