I have acid reflux, bile reflux, colonic inertia, hiatal hernia, and gastritis! I have some wicked digestive problems! my heartburn is so bad Im suppose to take two protonix a day, general people take only one! That doesn't seem to help me though my bravo surgery showed it did! I get pain that is so intense it affects my breathing (which is bad on the daily as is) and it send shooting pain into my back! My gi said the intense back pain is due to both of my reflux issues because the back is in the general area, the esophagus is radiating all that pain into all the general locations! I have had in my life so far 3 endoscopies, one was a bravo surgery and 2 colonoscopies! For some reason I found that pepto helps me better than the protonix and the gaviscon... I am suppose to take gaviscon before I eat (in addition 2 my two protonix a day)! Have you ever checked into getting a wedge for your bed (wedge pillow).? I haven't because they are expensive! Try to avoid eating at least 3 hours before bedtime... Of course Im sure you have a list of all the things to avoid... fried foods, caffine, spices, etc! I did want to let you know I feel your pain... I also have MVP which sometimes causes me chest pain... In addition to heartburn it is no fun! Definitely see the GI, this is not normal!