I have a female who is about 2. She was spayed young, about 6 months. She has always been a joy and no issues at all. Well, suddenly, last night, she went psycho. She is attacking our males. When she sees one of them she lets out a loud scream, puffs up, and attacks them. This is all unprovoked. My poor older male peed on the floor he was so scared. When they run to hide from her, she appears to hunt them. She is not doing this to our other female cat. All cats are fixed and have been for years. She otherwise is acting her normal self. I have never seen anything like this. Anyone have any ideas on what the heck could be going on?