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Hi Barbara,My name is Barb too! But, I go by Barbara. Anyhow, it sounds like you have been headed in the right direction.
I use the transdermal form of mirtazapine (Mirataz). My cat has been on it for quite a while now (2021), and I only give her 1/2 dose every other day. I switch it up if needed, but I have never yet given her a full dose. Funny thing about this appetite stimulant, at least in transdermal form, is that it can take hours to make an effect, or it can take a day - I just think it is also somewhat due to the food that is being given too as my cat has her preferences. If you are feeding multiple foods, which I have to do with my cat, I think that can contribute to the 'reaction'.
Let us know how the tests go.
I've never used the transdermal form of Mirtaz... only a 1/4 of a pill twice a week. It takes a few hours before it has an effect but last for hours. I'm curious, does the transdermal form make your cats whiny? Jengo whines the whole day! It does make him hungry but he still only eats a small amount every time he begs for food. Jengo has always been a fussy eater so it's hard to get enough food in him without supplementing by syringe feeding a meal or two.
Still waiting on Friday's test results as it was sent out to a lab instead of in-house.
Barb