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Thanks. There was definitely a reaction to the vaccine as he started vomiting a lot quite soon after he received it and went for antihistamine the next morning. My vet thinks it may have triggered or made worse something pre existing, but we don't really know. Honestly I feel guilty about how skinny he has gotten. I wish I had seen it sooner. I guess when you spend everyday together it can be hard to notice. It wasn't until his behaviour changed that I knew something was wrong. I have two cats and the other is a food thief so I didn't see that he wasn't eating very much. I have discussed with my vet and we probably won't be giving any more vaccines for him. He is indoor only and we just don't want to chance this type of event again.I'm so glad he's doing better. I think you're right it might have been dehydration that let to this. Vaccines are generally very safe, so it's hard to tell if it's the vaccine itself or just something that happened around that time. He could have been exposed to something at the clinic, some mild virus tummy or something and like you said, it just snowballed from there. He's so lucky to have an attentive owner who took notice in time and made him all better :rub: