I've never taken a sulfa drug for a sinus infection. That's interesting. I usually get Ceftin or Augmentin. I take an antihistamine/decongestant daily as well as Mucinex if my congestion is very severe. I have a deviated septum, so my sinuses are really whacked up. I also have an ongoing Rx for Nasonex. Can't take anything that starts with Aste- as those all make me sneeze. Can you take something like Mucinex or Mucinex D to help decrease the congestion?