Just got home from taking my best friend to Medac. This morning her cat, Twiggy, attacked her...really bad. This was a stray she took in about 6-8 mos. ago. The cat had recently been spayed as she still had stitches. She weighed a little over 3lbs., looked horrible and was very skittish. She took her to the vet and had her checked out and they gave her all her shots and wormed her. My friend has 8 other cats...4 adult and 4 kittens. She was nervous about bringing her in around the kittens so she keeps her in her laundry room which is a good sized room. It has a window and a door with windows and she loves to lay on the kitty condo in front of the windows. She lets her outside twice a day and the pretty much stays on the patio. She gets lots of attention and seems to love my friend. The first attack came when my friend tried putting her in the spare bedroom in the house. The put her in the room and about an hour later went in to check on her and the cat attacked her leg pretty bad. She had some antibiotics on hand and took them so no problem. She moved her back to laundry room after this. The second attack came when my friend opened the laundry room door and Twiggy saw one of the kittens and totally freaked out. She jumped from the washer onto my friends arm and wouldn't let go. She had to pry her off and she bit and scratched her several times. This time she had to go to the doctor. There have been a few minor incidents since but nothing major. It has been 2 mos. since the last bad attack until today. Today she went in and played with her, brushed her, gave her treats and left the door open so she could go outside. My friend brought in a new bag of cat food and went in the back door and Twiggy followed her in. She bent down and dropped the bag to the floor and Twiggy totally lost it. She has 8 bad bites on her hand, thumb and arm and is covered in deep scratches. Of course she had to see the doctor as it is so bad. Animal control had to be called and Twiggy will have to be quarantined for 10 days. My friend is pretty much feeling like she is going to have to have her PTS. She really doesn't want to but is scared of her now and she has diabetes and cannot risk these ongoing attacks. She doesn't want to adopt her out for fear of Twiggy attacking someone else especially a child. I just don't feel like this is normal behavior. I have two cats that are somewhat aggressive but nothing like this. They let you know when they are in a mood and when you need to back off. Twiggy attacks with no warning and afterwards it's as if nothing has happened. She is very loving. She is still a very skittish cat and very sensitive to loud noises but is much healthier now. The vet thinks she is about 2yrs. old and her weight is up to 7lbs. I'm sorry this is so long but wanted to include some history. Can anyone think of any underlying health problem that could be causing this behavior? Has anyone else experienced this type of behavior? I can't help but think that something is very wrong. Any input is greatly appreciated because I fear after the quarantine she will be PTS. Thanks!!