11 year old cat diagnosed with Triaditis

ipnotica

TCS Member
Thread starter
Kitten
Joined
Aug 4, 2023
Messages
7
Purraise
13
Hi everyone! I've been browsing this forum for the past few days and I decided to join because I could really use some advice. I'm sorry this post will probably be quite long because of all the background info. I just want to give you all the info I can so that I can best help my cat.

We adopted Paisley from a rescue in 2017 when she was approximately 5 years old. She is an only cat and she is indoor only. She was a bit overweight when we adopted her and she also had some issues with overgrooming but otherwise she was perfectly healthy. She is a very sweet kitty at home, but we soon found out that she is a terror at the Vet. This info might be helpful later in this post.

About a year ago, she became ravenously hungry. At the time we were feeding her 3 oz of wet food twice daily, at 4am and 4 pm, and I gave her treats once or sometimes twice a day. She started waking us up at 2-3am and sometimes even earlier because she was so hungry and she would start bugging me for her dinner at 1pm. Then she started losing weight. And avoiding her litterbox.

I scoop her box several times a day and wash it out once a week, so I didn't think it was a dirty box issue. I moved her box to a new location and that seemed to help momentarily, but then she started pooping on the carpet again about once or twice a week. I got her a new box and new litter which seemed to not help at all, so I switched back to the regular litter and now she has two boxes. Then she started vomiting. She has always had difficulty coughing up furballs but this was different. She would vomit several times a week and sometimes she would then eat the vomit. By now she was pooping outside of her litterbox almost every time, she was losing weight and she was still ravenously hungry.

I made an appointment with the Vet for July 11, which was about the same time she would have her yearly senior exam plus rabies shot and bloodwork for Revolution flea treatment. Because of the symptoms and behavior I had told them about, they wanted to get a full blood workup done on her, so they had to sedate her with Ketamine (because she tries to kill them every time she goes in). She was there for about 5 hours and they were unable to do her rabies shot or her test for the Revolution at that time.

The bloodwork showed that she was pre-hyperthyroid (which makes the always hungry and losing weight thing make sense) but what was most concerning was her elevated liver enzymes. They prescribed Hill's Prescription Thyroid food y/d (dry and wet) which I bought immediately and that's all I've been feeding her since. They also recommended an abdominal ultrasound which we scheduled for July 31st. They prescribed 2 capsules of Gabapentin for me to give her in a syringe mixed with tuna juice -- one the night before and the other the morning of her appointment. The dosing went surprisingly well and she was very well behaved all morning until I dropped her off at the vet at 8am. They were going to do the ultrasound and possibly a needle aspiration, her rabies shot and the bloodwork for her Revolution. They said they would call me when she was ready to be picked up, but I didn't hear from them until after 3:30pm, where they told me to pick her up at 4:30pm. They did give her the rabies shot, but only for one year rather than the three year she had been getting. They did not do the bloodwork for her Revolution, so I will have to bring her in again for that within a couple of weeks.

The ultrasound showed inflamation of her pancreas, liver and intestines. The vet called it Triaditis. They prescribed Prednisalone to reduce the inflamation, twice a day for 7 days, then once a day for 7 days, and then every other day until it's gone. As easy as it was to syringe her with the Gabapentin, let me tell you that the Prednisalone has been a complete nightmare. Paisley now seems to hate me, I'm a scratched up mess, and she has Prednisalone all over the fur of her neck. And this is only day 4!

And now I find out that I'm also supposed to give her 1 tablet of Denamarin by mouth once a day AND Ursodiol Soft Chew (compounded) once a day. I would probably be losing my mind right about now if she wasn't starting to gain weight, pooping in her box more often and not vomiting at all for the past few days. She is still ravenously hungry, though.

I like the vet that Paisley sees, but I have been wondering if I should take her to a different vet. Not because I think her current vet is incompetent, but because I feel like there's a disconnect somewhere in our communication. Yes, they do eventually call me back and try to answer my questions, but I just wonder why they didn't originally tell me some of the things I'm having to call them about later. For example, I had the vet tech come out and explain how to syringe the Prednisalone. However, she didn't tell me that there was a plastic cap inside the bottle with a small hole in it that the syringe didn't seem to fit into, so I was taking that thing off to draw up the medicine. I later found out that the syringe had to be really shoved into the inner plastic cap for a tight fit. Little things like that make me wonder if Paisley is getting the best care or if I'm just a complete idiot.

Anyway, long story longer, if any of you have any experience with this sort of thing, I'd really appreciate any and all help I can get. Thanks in advance ❤

Oh, and if the lab results would be helpful, I can post them too. Thanks again!
 

maggie101

3 cats
Top Cat
Joined
Apr 20, 2014
Messages
7,964
Purraise
10,029
Location
Houston,TX
I had a cat with triaditis. The prednisolone was compounded at a pharmecy fruity flavor. It was put in her food. The pred did majorly increase her appetite. First time doing it I had to ask the pharmecy for instructions. She lost a lot of weight from the triaditis. I wish I had used a different vet. And I should have taken her to a different internest. That was over 5 years ago so things have changed. Elura wasn't available then. It would have helped
 
  • Thread Starter Thread Starter
  • #3

ipnotica

TCS Member
Thread starter
Kitten
Joined
Aug 4, 2023
Messages
7
Purraise
13
Thank you for your reply, maggie101. The Prednisalone is cherry flavored. I mean, come on, really? What animal likes cherries? I think putting it in her food would be better. Maybe she would actually get a full dose that way.

I'm not familiar with Elura. Maybe I should ask the vet about it on Monday when she calls me back about the Denamarin and Ursodiol. I'm still thinking about looking for a new vet.

Thanks again for your help.
 

CHIKITTIES

TCS Member
Adult Cat
Joined
Feb 11, 2019
Messages
167
Purraise
182
I am so sorry to hear about your kitty's illness and your struggle giving her meds. I am currently giving 5mg prednisolone pill to my cats, using this method. Cat #1 took it immediately, Cat #2 needed 3 days before deciding this is better method than Mom squeezing pill into her mouth. Basically put pill in capsule, put it on non slippery surface, put a little food on top of it and let them lick. I use folded hand towel and churu, works like a charm. Smallest size 5 capsule fits prednisolone pill purrfectly.

Please help I’m struggling to give my cat medication
 

fionasmom

Moderator
Staff Member
Moderator
Joined
Jun 21, 2014
Messages
13,486
Purraise
17,785
Location
Los Angeles
I have used both Elura and Entyce (which is Elura for dogs). It is an appetite stimulant that works differently than cypro or mirtaz and is specifically designed and safer for animals with kidney issues. It is maple flavored, so again...what are they thinking. As was stated, it is proprietary and cannot be compounded or purchased otherwise. It is administered somewhat differently from other appetite stimulants and I found that it did not cause the ravenous appetite that can happen with the others.

Prednisolone for dogs and cats: Uses, Dosage & Side Effects
This is a well known and reliable compounding pharmacy. They will usually talk to you even if you do not have a prescription to give them.
 

maggie101

3 cats
Top Cat
Joined
Apr 20, 2014
Messages
7,964
Purraise
10,029
Location
Houston,TX
I have used both Elura and Entyce (which is Elura for dogs). It is an appetite stimulant that works differently than cypro or mirtaz and is specifically designed and safer for animals with kidney issues. It is maple flavored, so again...what are they thinking. As was stated, it is proprietary and cannot be compounded or purchased otherwise. It is administered somewhat differently from other appetite stimulants and I found that it did not cause the ravenous appetite that can happen with the others.

Prednisolone for dogs and cats: Uses, Dosage & Side Effects
This is a well known and reliable compounding pharmacy. They will usually talk to you even if you do not have a prescription to give them.
How does it work different than cypro or mirtaz?
 

mrsgreenjeens

Every Life Should Have Nine Cats
Staff Member
Advisor
Joined
Aug 13, 2009
Messages
16,467
Purraise
7,263
Location
Arizona
Since Paisley doesn't seem to have a problem eating, Iwould ask the Vet if it's ok to put her meds in her food and see if she'll take them that way. If not, both the prednosolone and Ursodiol can be compounded into a transdermal gel that can be rubbed into her ears. What I am wondering about that Ursodiol chew is if it's really ok to feed that with the throid diet? I always heard that when on that food they were not supposed to eat ANYTHING else or it would invalidate the effects of that food. A chew would seem to fall into that category of "anything else", and this could be why she is still ravenous. But, the hyperthyroid medication can also be compounded into a get to rub into her ear.

IF you could get her to take her meds as shown in the video, you might be able to get them all into one capsule and get her to take them take way if you had them in pill form, and if she was taking the thyroid medicine vs the thyroid food, you could indeed use Churu's to tempt her to take the capsule. Except for that darned Denamarin! I had a cat with liver issues and could never get her to take that one. Even the Vet techs could not get it into her! So we just didn't give it to her and used something else instead (like the Ursodiol)
 

white shadow

TCS Member
Top Cat
Joined
Nov 28, 2010
Messages
3,133
Purraise
3,081
Location
CA
How does it work different than cypro or mirtaz?
Hi maggie101 maggie101 !

"Tanya's Comprehensive Guide..." has a reliable, thorough and plain-language coverage of that right here: Capromorelin (Elura or Entyce).

The author also offers some personal commentary there (some red flags for me) and some anecdotal reports from folks who paricipate/d in her online support groups.

(If you'd like similar for other commonly-used appetite stimulants, that's here.)

I remember that, when "Elura" was first introduced and discussed here on TCS a few years ago, folks were generally not impressed with it.
 

BellaBlue82

Sadie rules, Julian drools, my boys rule heaven ❤
Alpha Cat
Joined
Mar 15, 2022
Messages
397
Purraise
958
Location
Pittsburgh PA
While I don't have experience with triaditis, I have experience with a beautiful tabby who was unruly at the vets office. It got to the point he fought through sedation and attacked me because he was so dopey he didn't recognize me.
This was my driving force behind finding a different vet. I finally decided on a mobile vet who comes to our house; that journey started in 2011 and honestly has helped more than I know. While she is not an emergency vet, she has been more reliable than any vet I had previously. She was more compassionate with our first tabby, she was there for three life threatening conditions and guided me through each of their care.
Since the beginning she has been open to alternative medicine, discussing options, and treatment plans. At this point, I have her personal phone number to call for advice in an emergency just in case.
I'm not sure if a mobile vet is an option where you live, but I do agree with maybe looking into another vet/clinic if you have a gut feeling about it.
Another thing that I thought of is if Paisley might have diabetes? Our GA cat had many similar symptoms - ravenous, loosing weight, inflammation of the pancreas, and litter box mishaps. But if it seems she's gaining weight on the new food, it might be a moot point.
As far as administration of meds, yeah that can be a challenge lol. One gets prednisolone twice a day, one got diabetes tested and shots twice a day, one got liver medications and fluids twice a day. Don't beat yourself up if it doesn't go as planned. It takes time for both of you to get used to a regime that works for the two of you, and even then they can randomly decide to "argue" with it. If that happens, try to stay calm and just walk away. Let them cool down and try again in another half hour.
Sending you prayers, I hope Paisley continues to improve!
 

fionasmom

Moderator
Staff Member
Moderator
Joined
Jun 21, 2014
Messages
13,486
Purraise
17,785
Location
Los Angeles
Elura works directly on the hunger center in the hypothalamus. Mirtazapine increases noradrenaline and serotonin and is technically an anti-depressant.
I have been personally underwhelmed with the effectiveness of both Elura and Entyce, but that is only my anecdotal observation of those products.
 

silent meowlook

TCS Member
Staff Member
Forum Helper
Joined
Nov 10, 2014
Messages
3,586
Purraise
6,747

The above article gets very in depth. It is written for veterinarians mostly. Warning there is a surgery picture in there that might be disturbing to some, as well as some pictures of very ill cats.
I always think an internal medicine specialist is best for this type of illness as it is very complex. It helps allot to have a vet with additional knowledge, education and experience.

As for the medications. You will only damage your relationship with your cat trying to give them a cherry flavored medication. Also, some of the liquid flavored medications are for children and have artificial sweeteners in them that are bad for animals. If you can do it, it is much better to give your cat a pill than to mess around with the disgusting flavored children's medications.

One option if you can't give a pill, is to have the medication compounded through a reputable pharmacy. I like Wedgewood Pharmacy. They make many different formulations of medications for cats and dogs, You can even pick the flavor. Examples are chicken, fish and other flavors that cat's like. With my cat it actually comes out less expensive for me to have her chemotherapy pills compounded into chicken flavor tablets.
 

silent meowlook

TCS Member
Staff Member
Forum Helper
Joined
Nov 10, 2014
Messages
3,586
Purraise
6,747
Elura works directly on the hunger center in the hypothalamus. Mirtazapine increases noradrenaline and serotonin and is technically an anti-depressant.
I have been personally underwhelmed with the effectiveness of both Elura and Entyce, but that is only my anecdotal observation of those products.
I agree with that about the Elura and Entyce. Very underwhelmed.
 

Alldara

TCS Member
Staff Member
Forum Helper
Joined
Apr 29, 2022
Messages
5,556
Purraise
9,459
Location
Canada
For the prednisolone for Magnus I put a bit of Churu on my finger, then the pill, then more Churu. It sometimes takes me doing this twice before he will eat it but it worked well.

Ours isn't flavoured though.
 

daftcat75

TCS Member
Top Cat
Joined
Sep 7, 2018
Messages
12,719
Purraise
25,268
I encourage you to get an internal medicine specialist on your team. They will have the experience and expertise your regular vet probably does not have. They'll have seen more of these cases and have a better idea of the common pitfalls, challenges, and concerns.

Like CHIKITTIES CHIKITTIES , I pack Betty's pred into size five capsules, dip them in something highly appealing, and drop them on the carpet for her. Instead of Churu, I use Hills A/D. One can lasts us a week. I call it Betty's "cake frosting" because she will eat just about anything if it has some A/D on it. She stopped liking her Dasuquin treats. But then I started putting just a tiny amount of A/D on top of them and she looks forward to them again. She always shows up and takes her meds. But sometimes she doesn't eat anything after. So I take a bit of the A/D remainder after her meds and smear that atop her food ("starter strips.") That works and now I'm assured she's taking her meds with food. When the meds kick in, she'll return to the plate and finish it. Betty takes three capsules twice a day using this method below. It cannot be any simpler to medicate her. Unlike others, if I get a liquid medicine, I have it compounded back into a pill or capsule because I know Betty will take capsules on her own. No more medicine wrestling matches.

 
  • Thread Starter Thread Starter
  • #16

ipnotica

TCS Member
Thread starter
Kitten
Joined
Aug 4, 2023
Messages
7
Purraise
13
Wow! Thank you all so much for sharing your knowledge, tips and experiences with me. It's obvious how much you love and care for your kitties. Not just your own, but all kitties.

I've started giving Paisley her dose of Prednisolone mixed with a small amount of tuna juice on a saucer. She loves it like I'm giving her a treat. It's so much better than trying to syringe it down her throat and she's definitely getting the full dose now. It seems to be working really well, too. She hasn't vomited all week and she's using her litterbox normally again. Yay!! She also appears to be gaining some weight, she's more energetic and she's spending more time interacting with us. I'm so happy she's feeling better :)

After speaking with the vet and a couple of vet techs from the hospital, I've decided to order the Denamarin and the Ursodiol. I can give her the Denamarin tablet in a pill pocket. I'm thinking about just giving her an empty pill pocket the first time so hopefully she'll think it's a treat and gobble it up the next time when the pill is in it. The Ursodiol is a soft chew which supposedly tastes like salmon so she'll probably like that. We'll see how it goes...


I'm trying so hard to do what's best for her, but I want her to be happy, too. It's difficult to know what to do sometimes. I'm so grateful for your help and well-wishes. You guys are the best and I appreciate you more than you know.
 
  • Thread Starter Thread Starter
  • #17

ipnotica

TCS Member
Thread starter
Kitten
Joined
Aug 4, 2023
Messages
7
Purraise
13
Just wanted to give you guys an update ❤ Paisley has been doing great on the Prednisolone, now that I can actually get it down her throat. Today she started the third cycle, which is every other day until it's gone. I think she might be really disappointed when that day comes lol

She also had her first dose of Denamarin today. I put it in a Greenie's pill pocket and she gobbled it up as if it were a treat. She's still using her litterbox normally and not vomiting at all. We'll see how it goes when she finally gets the Ursodiol, but so far so good 🤞
 
Top