This should give you a general idea
Pyriproxyfen (Nylar, Archer) is a product of Virbac that is a new third generation Insect Growth Regulator (IGR) - Juvenile hormone mimic. Pyriproxyfen (an IGR) + permethrin (a synthetic pyrethroid insecticide) (Knockout) kills adult fleas and ticks plus kills flea eggs for dogs. Also, Knockout is formulated as a room and area fogger, killing adult and preadult fleas for seven months plus ticks, cockroaches and spiders.
If the homeowner treats the pet, spot-ons, powders or dusts are preferred over sprays. Put on rubber gloves and apply the product thoroughly into the hair coat according to label directions. Cats are more susceptible than dogs to toxic effects of many insecticides since they groom themselves. Flea collars cannot always be relied upon to bring existing infestations under control. Collars do not kill existing premise infestations. Some animals are sensitive or allergic to collars. Watch for signs of dermatitis on the neck under the collar. Some labeled pet collar insecticides include: Pyrethrins, resmethrin, carbaryl (Sevin), diazinon, naled, tetrachlorvinphos (Rabon) + methoprene (Precor), d-limonene + linalool, rotenone, propoxur, allethrin and permethrin (Bio Spot) for dogs only. Amitraz collars labeled for dogs only are effective on ticks. After 24 hours, 95 percent of attached ticks become detached.http://www.straightgoods.ca/ViewFeature.cfm?REF=88