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L-Lysine questions please.....

post #1 of 43
Thread Starter 
My amidala.gif Perla has been dealing with a very, very bad herpes virus that just won't let go. I just want to pick some brains on the Lysine front. thanks.gif Much appreciated......smile.gif

1. What is the highest, safe dose you can give a cat daily who is suffering a herpes flare-up?
2. How long can you give that highest dose of Lysine each day i. e. one week? two weeks? before you go down to the maintenance dosage.
3. Is it really safe to give the maintenance dose of 250 mg./day for a cat who is permanently infected and shedding the herpes virus?
4. (this may be a dumb one... but) Does the Lysine lose it's effective benefit's against herpes flare-ups if the cat has been on and off the supplement for many months?

My vet's both say only 500 mg. per day - but that is not helping her. If I go to 1000 mg. per day I see a slight improvement. But vet's do not recommend that dosage. I don't want to "overdose" her on Lysine sigh.gif Thanks for your responses in advance hugs.gifbiggrin.gif
post #2 of 43
Quote:
Originally Posted by Feralvr View Post

My amidala.gif Perla has been dealing with a very, very bad herpes virus that just won't let go. I just want to pick some brains on the Lysine front. thanks.gif Much appreciated......smile.gif
1. What is the highest, safe dose you can give a cat daily who is suffering a herpes flare-up?
2. How long can you give that highest dose of Lysine each day i. e. one week? two weeks? before you go down to the maintenance dosage.
3. Is it really safe to give the maintenance dose of 250 mg./day for a cat who is permanently infected and shedding the herpes virus?
4. (this may be a dumb one... but) Does the Lysine lose it's effective benefit's against herpes flare-ups if the cat has been on and off the supplement for many months?
My vet's both say only 500 mg. per day - but that is not helping her. If I go to 1000 mg. per day I see a slight improvement. But vet's do not recommend that dosage. I don't want to "overdose" her on Lysine sigh.gif Thanks for your responses in advance hugs.gifbiggrin.gif

1-L-Lysine is water soluble and it is really hard to overdose on..... The maintenance dose here in my house is 500mg/day, 250mg am and pm and the dose during flare ups is 1000mg a day.
2- for as long as necessary
3- yes, Lysine can be given for life - there is absolutely no harm to do so.... on the contrary.....
4- never heard of it...... not to say that it doesn't happen, but I never heard of it - it is not an antibiotic - it is just an amino-acid that prevents the virus from multiplying; thus I do not think that they get a resistance.
To your question/your vet's concern - you will not overdose her - she will use what she needs, and the rest will be disposed of via her urine agree.gif
post #3 of 43
Thread Starter 
Thank you, Carolina hugs.gif. You have put my to rest about having to give her 1000 mg. per day for now till she improves. thanks.gif
post #4 of 43
Quote:
Originally Posted by Feralvr View Post

My amidala.gif Perla has been dealing with a very, very bad herpes virus that just won't let go. I just want to pick some brains on the Lysine front. thanks.gif Much appreciated......smile.gif
1. What is the highest, safe dose you can give a cat daily who is suffering a herpes flare-up?
I gave my F3 Savannah, 1,500 mg/day during his worst flair up. That was thank God, almost a year ago. I thought I was going to loose the cat. I credit Lysine with saving his life.
2. How long can you give that highest dose of Lysine each day i. e. one week? two weeks? before you go down to the maintenance dosage.
My Savannah got between 250 mg/day to 1500 mg/day for a month. Then, once symptoms got better, he got less Lysine. Once his flair up was "over", he got 125 mg/day every other day for a week. After that, he got NONE. It has been several months and he has not had a flair up, hence no Lysine.
3. Is it really safe to give the maintenance dose of 250 mg./day for a cat who is permanently infected and shedding the herpes virus?
Safe yes, but, not necessary, in my experience.
4. (this may be a dumb one... but) Does the Lysine lose it's effective benefit's against herpes flare-ups if the cat has been on and off the supplement for many months?
I have found it to be MORE helpful, not LESS!
My vet's both say only 500 mg. per day - but that is not helping her. If I go to 1000 mg. per day I see a slight improvement. But vet's do not recommend that dosage. I don't want to "overdose" her on Lysine sigh.gif Thanks for your responses in advance hugs.gifbiggrin.gif
I am fairly sure, you can NOT overdose your cat on Lysine. My vet, thinks I am nuts for swearing by Lysine. Be glad your vet at least acnologes it as a useful form of treatment for feline herpes.


 


Please note, my answers are in red font.

 

*These are my experiences as a cat owner, based on ONE hybrid exotic cat** **I have NEVER used it on a pure domestic**

post #5 of 43

My vet told me to give my cats 500 mg twice a day (total 1000 mg a day) during flare-ups, for as long as the flare-up occurs. The rest of the time, when I was using Lysine treats I gave them up to two 250mg lysine treats per day so up to 500mg a day but sometimes less. Nowadays unless someone is having a URI, I just sprinkle it on their dry food because most of my cats won't eat it in treats or mixed in wet food and it's too stressful for them to force a pill on them every day if they're not having any symptoms.

I actually don't know if they do have herpes but my vet says the lysine won't hurt so I might as well do it. We do think one of my cats Church has the infection but he hasn't had a flare-up since he was a kitten. I've read that some cats do "outgrow" it like that.

post #6 of 43
Quote:
Originally Posted by Nekochan View Post
 I've read that some cats do "outgrow" it like that.


I sure hope my Savannah is one of those cats! Was that in some type of "scientific" or veterinarian literature?

 

post #7 of 43

The important thing to know about Lysine is that it needs to stay in the kitty's system, so it needs to be given every 12 hours as it's shed in urine.  Also, it can take up to 6 weeks to see any benefit of Lysine.

post #8 of 43
Thread Starter 
Thank you all SO much for your responses. Much appreciated. OK - I must always give it twice daily - I absolutely do that when giving the 1000 mg. - divided into two doses. BUT when she was only getting 500 mg. per day, I was only giving it in the morning. That could be part of the issue with the Lysine not working well enough - giving it once daily.. biggrin.gif
post #9 of 43
Quote:
Originally Posted by Feralvr View Post

Thank you all SO much for your responses. Much appreciated. OK - I must always give it twice daily - I absolutely do that when giving the 1000 mg. - divided into two doses. BUT when she was only getting 500 mg. per day, I was only giving it in the morning. That could be part of the issue with the Lysine not working well enough - giving it once daily.. biggrin.gif

Ohhhhh yeah - it must be given in two doses - always - glad Stephanie wrote that in there agree.gif
post #10 of 43
Thread Starter 
Quote:
Originally Posted by Nekochan View Post

I actually don't know if they do have herpes but my vet says the lysine won't hurt so I might as well do it. We do think one of my cats Church has the infection but he hasn't had a flare-up since he was a kitten. I've read that some cats do "outgrow" it like that.
Quote:
Originally Posted by Cat Person View Post



I sure hope my Savannah is one of those cats! Was that in some type of "scientific" or veterinarian literature?

I have not read that - hmmm.gif BUT that would be great to know if that is possible. I just know that once they are infected with the Herpes - they are carriers/shedders of the virus for life frown.gif...... some never have any flare-ups whatsoever BUT if the cat has some immune disorder then the Herpes will rear it's ugly head paranoid.gif and also come on under times of great stress.

Thanks again for your responses hugs.gifwink.gif
post #11 of 43
Quote:
Originally Posted by Feralvr View Post


I have not read that - hmmm.gif BUT that would be great to know if that is possible. I just know that once they are infected with the Herpes - they are carriers/shedders of the virus for life frown.gif...... some never have any flare-ups whatsoever BUT if the cat has some immune disorder then the Herpes will rear it's ugly head paranoid.gif and also come on under times of great stress.
Thanks again for your responses hugs.gifwink.gif


No, pure domestic cat, I have ever owned, ever had a flare up. Or, at least a noticeable one(s).

 

Anyway, I want to add, I gave my F3 Savannah, 3 doses daily (when giving 1,500 mg/day), mixed in some canned food. In order, to make sure he ate it ALL. I found making sure the cat ate it ALL, per "session" helped the Lysine work quicker. I saw "results" in seventy two hours, but, my Savannah was on deaths door.

 

I also found, opening my windows, in the warmer months, helped get rid of the virus. I have been told that outside air can help kill the virus. I am NOT sure if that is true. But, it seemed to help my cat.

 

*Please note, these are my experiences, based on ONE hybrid exotic cat!*

post #12 of 43
Thread Starter 
Quote:
Originally Posted by Cat Person View Post



No, pure domestic cat, I have ever owned, ever had a flare up. Or, at least a noticeable one(s).

Anyway, I want to add, I gave my F3 Savannah, 3 doses daily (when giving 1,500 mg/day), mixed in some canned food. In order, to make sure he ate it ALL. I found making sure the cat ate it ALL, per "session" helped the Lysine work quicker. I saw "results" in seventy two hours, but, my Savannah was on deaths door.

I also found, opening my windows, in the warmer months, helped get rid of the virus. I have been told that outside air can help kill the virus. I am NOT sure if that is true. But, it seemed to help my cat.

*Please note, these are my experiences, based on ONE hybrid exotic cat!*

I am glad your Savannah survived the virus and sorry he was so sick hugs.gifheartpump.gif. I also make sure Perla eats up all of the Lysine - so far so good with her eating it up as I mix with her favorite wet foods. I wish I could open up the windows - it is in the twenties. BUT I could certainly breeze the house for a few minutes to get some fresh cold air through here. HMMMMM - good idea - and sound's cold.gif but refreshing. happy2.gif
post #13 of 43
Quote:
Originally Posted by Feralvr View Post


I am glad your Savannah survived the virus and sorry he was so sick hugs.gifheartpump.gif. I also make sure Perla eats up all of the Lysine - so far so good with her eating it up as I mix with her favorite wet foods. I wish I could open up the windows - it is in the twenties. BUT I could certainly breeze the house for a few minutes to get some fresh cold air through here. HMMMMM - good idea - and sound's cold.gif but refreshing. happy2.gif


I am not sure, if, you need to do it in cold whether. If, you try it, let me know if it helps any. Hope Pearla gets better soon.

post #14 of 43

Feralvr, are you absolutely sure your cat has a viral infection and not a bacterial infection? I had two veterinarians prescribe L-Lysine for my two cats who were having a bad herpes virus flare-up. They said it was a viral infection and did not want to prescribe antibiotics. A few years later the symptoms were still bad and a third veterinarian decided it wouldn't hurt to try Clavamox for a week and the symptoms (mainly eye discharge) began to disappear. We ended up giving the cats two weeks worth of Clavamox and all their URI/herpes virus symptoms disappeared. I was shocked and upset that the first two vets were wrong and wonder what kind of damage was done to my cats after having a misdiagnosed bacterial infection for that many years.

 

About once or twice a year the one cat has a little flare-up but it eventually goes away with some L-Lysine. This year I suspected a bacterial infection since it wasn't improving and asked the vet for some antibiotics. It took three weeks worth of Clavamox to finally clear everything up. So you may want to try Clavamox if nothing else is working, it could be a bacterial infection.


Edited by lilblu - 1/18/12 at 2:01pm
post #15 of 43

Regarding cats "growing out" of the flare-ups, I don't know whether there are any studies on this, but I heard it from my vet and know of several others whose vets said the same thing. If you do a search online for cats growing out of "flare-ups" or recurring URIs from feline herpes you will find a lot of other people saying the same thing as well. All I know from personal experience is my cat Church had the repeated URIs as a kitten, which my vet diagnosed as feline herpes and he has not had one since he grew up, even during stressful times such as a cross-country flight and move to a new house.

post #16 of 43
Quote:
Originally Posted by Nekochan View Post

Regarding cats "growing out" of the flare-ups, I don't know whether there are any studies on this, but I heard it from my vet and know of several others whose vets said the same thing. If you do a search online for cats growing out of "flare-ups" or recurring URIs from feline herpes you will find a lot of other people saying the same thing as well. All I know from personal experience is my cat Church had the repeated URIs as a kitten, which my vet diagnosed as feline herpes and he has not had one since he grew up, even during stressful times such as a cross-country flight and move to a new house.


I know personally a cat that had very bad herpes for about the first year of his life, he was constantly sneezing blood all over everything.  He has been symptom-free for about 5 years now with no lysine ever.
 

 

post #17 of 43
Quote:
Originally Posted by Cat Person View Post


 

I also found, opening my windows, in the warmer months, helped get rid of the virus. I have been told that outside air can help kill the virus. I am NOT sure if that is true. But, it seemed to help my cat.

 

*Please note, these are my experiences, based on ONE hybrid exotic cat!*


I was wondering about that.  We will be moving into a house with a fenced yard in April and I have been looking forward to finding out if being outside sometimes will improve the health of my kitty.
 

 

post #18 of 43

My vet recommended 1000 mg daily as a maintenance dose. That's what it says on the tub the medication comes in as a recommended dose, as well. He still has flare-ups with that, so during the start of one we'll give him 1500 and it seems to help somewhat.

post #19 of 43

I am not too familiar with L-Lysine but I know you can gets cat treats for L-Lysine.

post #20 of 43

My cats receive 100o every day. Remy has FIV and FHV, Desmond has FHV. If I lower the dosage for Remy he is a mess ( eyes tearing,etc.) If I lower it for Desi he starts sneezing. I recently added Bovine Lactoferin and I think that is helping too. My vet says to five it for life. I buy the power on Amazon, so much easier to just sprinkle it in the food. My cats won't eat the treats.

post #21 of 43

Sorry  that should read ' give it for life'

post #22 of 43

I am fairly certain my cat Yoda has the herpes virus and has passed it to my other cat King. Yoda shows much more severe symptoms than King, i.e. very bad eye discharge that causes his long fur to mat up and his eyes get crusted shut, very bad sneezing and congestion sometimes with blood and during a very bad flare up he wheezes. King has mild eye discharge and sneezing. I am certain it's not a bacterial infection because the vet has given many different antibiotics with no success, he gets better for about a week maybe 2 (not cured mind you, just better) then it's right back to the bad symptoms. Now I say that I am fairly certain it's herpes, but as the vet has not brought it up, I am not 100%. Though, seeing as Lysine is not harmful to cats, I figured I'd give it to them and see if they get better, especially Yoda. 

post #23 of 43
Hi there! I really hope someone can help me. My hubby and I just adopted a kitten from our local shelter who had a URI a few months before we got him. We brought him into a house with 4 other cats who were perfectly healthy. A few weeks later he started sneezing really bad so I took him to the vet and he was put on Doxycycline... Which really helped him. The very next week, one of our cats started sneezing and doing this weird thing with her head, so I took her to the vet and they put her on Clavamox and Carafate. The very next day she stopped eating. I had to syringe feed her for several days and took her to a different vet who gave her IV fluids and switched her over to the Doxycycline. Then 2 more of our cats started sneezing, so I immediately started them on the Doxy. Then a couple days later, our last cat got it. I ended up taking the cat who want eating back to the vet and she put her on Mirtazipan... An appetite stimulant and also some other drug that is a antihistamine. Now she is at least eating on her own. This has all taken place over the last 11 days. I was reading online about L-Lysine, so I just went to Petsmart and picked some up and gave them all their first dose. How long does it usually take for the L-Lysine to take effect and really help their URI? After the URI is cleared, should I continue to keep them on the l-lysine as a maintenenc? As you could imagine, its been quite sad and stressful trying to care for 5 cats with URIs, so any suggestions on what I can do to prevent it from coming back, it would be soooo greatly appreciated. I just love my fur babies so much and it hurts me to see them sick. Thanks so much for your help!!!!!
post #24 of 43
Quote:
Originally Posted by ctimney View Post

Hi there! I really hope someone can help me. My hubby and I just adopted a kitten from our local shelter who had a URI a few months before we got him. We brought him into a house with 4 other cats who were perfectly healthy. A few weeks later he started sneezing really bad so I took him to the vet and he was put on Doxycycline... Which really helped him. The very next week, one of our cats started sneezing and doing this weird thing with her head, so I took her to the vet and they put her on Clavamox and Carafate. The very next day she stopped eating. I had to syringe feed her for several days and took her to a different vet who gave her IV fluids and switched her over to the Doxycycline. Then 2 more of our cats started sneezing, so I immediately started them on the Doxy. Then a couple days later, our last cat got it. I ended up taking the cat who want eating back to the vet and she put her on Mirtazipan... An appetite stimulant and also some other drug that is a antihistamine. Now she is at least eating on her own. This has all taken place over the last 11 days. I was reading online about L-Lysine, so I just went to Petsmart and picked some up and gave them all their first dose. How long does it usually take for the L-Lysine to take effect and really help their URI? After the URI is cleared, should I continue to keep them on the l-lysine as a maintenenc? As you could imagine, its been quite sad and stressful trying to care for 5 cats with URIs, so any suggestions on what I can do to prevent it from coming back, it would be soooo greatly appreciated. I just love my fur babies so much and it hurts me to see them sick. Thanks so much for your help!!!!!

 

So sorry to hear your babies are sick! I adopted a 6month old kitten from a rescue a little over a year ago. To make a long story short, he had feline herpes (even though she said he was healthy- her vet couldn't verify who the cat was). I started all my cats on L-Lysine (the powder because it lasts longer and easier to put into food). I was using it daily as a maintenance up until a few months ago. I began working at a vet's office and one of the vets had recently read an article on the Lysine that said there were issues using it like that (that didn't show until years down the road). However, she said it was fine to use when they began showing symptoms. She could not remember specific issues that the cats had.

 

So, I use it for all my cats when one cat begins to show symptoms (sneezing, "winking", runny eyes), and I use it for about a week after all symptoms stop for all my cats. Since URI's and Herpes are highly contagious, I just bet that if one has it, they'll all have it. So far, using it like this has helped with their outbreaks, and it saves me money and product since I'm not using so much. They've only had one outbreak since I cut back.

post #25 of 43
Quote:
Originally Posted by BekkaCat View Post
 

I am fairly certain my cat Yoda has the herpes virus and has passed it to my other cat King. Yoda shows much more severe symptoms than King, i.e. very bad eye discharge that causes his long fur to mat up and his eyes get crusted shut, very bad sneezing and congestion sometimes with blood and during a very bad flare up he wheezes. King has mild eye discharge and sneezing. I am certain it's not a bacterial infection because the vet has given many different antibiotics with no success, he gets better for about a week maybe 2 (not cured mind you, just better) then it's right back to the bad symptoms. Now I say that I am fairly certain it's herpes, but as the vet has not brought it up, I am not 100%. Though, seeing as Lysine is not harmful to cats, I figured I'd give it to them and see if they get better, especially Yoda. 

 

Even if your vet hasn't brought this up, I urge you to. Herpes is not curable, but the symptoms/outbreaks are treatable. Please see my above post, if you'd like more info on the Lysine. 

post #26 of 43
Hi there! I am actually dealing with the same situation right now. Everything you mentioned, my cat Sandy has... and it's definitely Herpes. My vet took one look at her and knew right away! I've got her on a bunch of things... an eye cream 2 times a day, an antibiotic 3 times a day, l-lysine every 12 hours and I'm still waiting for some eye drops to come in the mail. This all stemmed from an upper respiratory infection spread from a cat we adopted from a local animal shelter. Sandy was just diagnosed with the herpes a few days ago, so I totally know what u are going thru. We have 4 other cats, so I'm trying to keep her away from them as much as I can. Thankfully, my vet said it cannot be transmitted to humans or dogs, so don't worry about that. I'm not sure how long the outbreak is suppose to last, but Im hoping all these medicines will help her. I hope this was helpful for you and I hope your little one feels better soon! ~Christy
post #27 of 43

Just wanted to thank everyone for sharing your experiences on this thread. :-)

 

My vets haven't really given me much guidance re: dosage for my FIV/FHV kitty, and I was afraid of overdosing him if I gave him a 500 mg. scoop twice a day per the instructions on the container.  Now I feel encouraged to give it a try.  Bless his heart, it seems like every time I turn around, he has another flare-up of some kind.  I really need to stop turning around so often. ;-)

post #28 of 43
No problem! I'm glad that my experience so far has been helpful. It has also been helpful for me to read everyone else's posts too! Here is a list of the mess my vet gave me for Sandy's herpes.... the l-lysine is called Enisyl-F (it's a paste they gave me at the vet), the antibiotic is called Famciclovir (it's a tablet), the eye cream is NeoPolyBac OphO, and the eye drops I'm still waiting to receive so I don't know the name. For my other cats, I got a different l-lysine to give them to help boost their immune system since they all had the upper respiratory infection. The brand is Simply Nourish and it is a 125mg soft chew that looks like a treat. I got them at PetSmart. It says to give a small portion of the treat at meal time over 7days, increasing the amount each time until they get the whole treat. Two of my cats will eat it on its own, but the other ones I have to break up and hide it in their food. As for the l-lysine paste for Sandy, I measure the prescribed amount into a syringe and mix it with her food. It's only been a few days so far, so I'm keeping my fingers crossed that all this helps. I will keep you updated! Good luck with your little one too!!!! ~Christy
post #29 of 43
Quote:
Originally Posted by ctimney View Post

No problem! I'm glad that my experience so far has been helpful. It has also been helpful for me to read everyone else's posts too! Here is a list of the mess my vet gave me for Sandy's herpes.... the l-lysine is called Enisyl-F (it's a paste they gave me at the vet)...

 

Huh.  I've accidentally stumbled across Enisyl-F before when ordering some Vetoquinol L-Lysine, but that's about the extent of my knowledge on the subject. ;-)

 

Is that something you can give cats in addition to L-Lysine?  Or is it an either/or kind of thing? *iz so embarrassed*

post #30 of 43
Quote:
Originally Posted by cheeser View Post

Huh.  I've accidentally stumbled across Enisyl-F before when ordering some Vetoquinol L-Lysine, but that's about the extent of my knowledge on the subject. ;-)

Is that something you can give cats in addition to L-Lysine?  Or is it an either/or kind of thing? *iz so embarrassed*
The Enisyl-F is l-lysine. smile.gif It is a prescription brand given to me at the vet for Sandy (the one with the eye herpes). I give that to her only! The other Simply Nourish L-lysine treats are the ones I give to my other cats since i got it over the counter at PetSmart. I know all of this is very confusing. I'm really just learning as I go too wink.gif
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