Hi Shrimp's mom, I just came across this conversation, and wanted to ask if you ended up trying the Transdermal Prednisolone, and if so, whether it was better than the other version of prednisolone? My cat has either IBD or lymphoma per her ultrasound (we did not biopsy yet) and we tried prednisolone as she was having partial soft poop for 2-3 months. Probiotic Visbiome helps and she is on i/d canned food. Prednisolone had a terrible reaction where she had liquid diarrhea from a single dose 5 mg. and vet told us to stop it right away. Her diarrhea didn't resolve for almost a week, during which she was dehydrated and I had vet come into do her subcutaneous fluids twice. Now, our vet prescribed her the transdermal, and I will eventually try but letting her recover a few more days. We don't have her B12 result back yet, her B12 two months ago was very normal so she never got b12 injections. BTW, I also asked my vet about Budnesonide but vet said that if our cat has the issue of steroid (or other drugs too) just going through her GI system, she will likely have diarrhea with Budnesonide too. I hope your cat is doing better!My cat possibly has IBS (We cannot afford to do a biopsy and given her symptoms the vet has prescribed prednisolone, 5 mg a day). My question is, how long does the medication (pill) take to work in terms of reducing her inflammation? More importantly, I hear that one side effect is increased appetite and I want to know how long that takes to take effect? She is eating but given her weight loss I want her to gain weight. I have read prednisolone can take a couple of weeks to work and some other places online say a couple of hours so I am confused. I really want her to start gaining weight and wonder if this is enough and i just need to wait or if she may need something like mirtazapine in conjunction.
Also, if cats with IBS have a hard time absorbing things, then how can she absorb the prednisolone pill? Would the liquid be better? Or is prednisolone absorbed in the stomach as opposed to intestine where the inflammation possibly is, so it wouldn't matter.