Hissing from an aerosol/spray can always scares cats. Don't use flea control unless you actually see fleas. some of my cats have never needed it. things like wound spray, etc. I spray on a cotton ball or small rag until they are soaked and apply it. This way the hissing does not affect the cat. the brushing may be hurting him. Get a soft-bristled brush and start with that, brushing just a few strokes for a few days and progressing from there. Starting around teh head area where they usually enjoy it. some cats don't like brushing at all, I have one right now, and naturally, it is teh long hair one.