Cat cancer growth

Sherrybaby77 · Mar 20, 2022

Hi,
I have an 18 year old cat that has a cancerous growth on her chin. She has been to the vet, and animal dermatologist. I have been told it’s cancer and it can not be removed because she has a heart murmur and high blood pressure which she is on medication for. If I put her under the vet said there is a high chance she won’t wake up. I have no choice but to leave it alone.
She still eats and drinks on her own, is not in pain, but her food gets stuck on the growth and I have to clean it which irritates it. I feel horrible not doing anything as it gets bigger and I don’t know what else I can do to help her. She isn’t suffering. Any suggestions would be helpful. I have attached a picture of the growth…just a warning is not a pretty growth.

FeebysOwner · Mar 21, 2022

Hi. I really don't have any great ideas on how to keep that clean, but you could try to use chamomile tea bags. You can buy them at most any grocery store as those are usually German (you don't want English, or any flavorings or additives). Brew a bag in water, cool the liquid to room temp, and then just use cotton balls to dab the liquid on that growth. Hopefully, just the 'dabbng' action will remove most of the food. No need to wipe it off, as it is safe for your cat to ingest. The tea has soothing and healing properties and is considered an anti-bacterial/anti-fungal agent as well.

fionasmom · Mar 21, 2022

I had a 17 year old cat who developed something that looked almost identical with the exception of the fact that it was growing out of her ear. The vet flat out refused to operate because of her age and other conditions...and I would probably not have done the surgery regardless.

The chamomile tea bags are an excellent idea. Basically, don't use anything that could sting or burn, even if you think that it is cleaning the lesion. If she will let you hold a moist teabag next to it in order to loosen the food, it will come off easier.

NadiaRey · Mar 21, 2022

I think I can help. This is exactly what my cat Sueño had. Back when she had a few weeks to live, I went and did a lot of research, and came up with a homemade treatment that I wished I had months before that. And I often think if I had another chance, I would do a lot of things differently. So here's what I'd do with what I know now (and what I kind of did).

I'll give you all the relevant information I gathered.
Please read everything before you try anything.

Method: Intralesional Treatment.
Intralesional Immunotherapy for Metastatic Melanoma: The Oldest and Newest Treatment in Oncology

Background: So, back during a test for a cancer treatment using lasers, they painted the tumor with a contrast tincture used commonly in medicine, so they could check how was the size of the tumor before and after using the laser. Well, it turns out the tumor started dying from the tincture alone, even before they used the laser. That's how, purely by accident, they discovered that the Bengal Rose tincture was a powerful anti-tumoral.
And also, that you can kill a tumor more efficiently by injecting it directly with an anti-tumoral agent.

So, yes, I'm telling you there's a treatment where you yourself can inject something to a tumor to kill it.

More info on Rose Bengal tincture (PV-10).
Description: coloring tincture (WARNING: 10% alcohol in the formulation) approved for use in the diagnosis of ocular lesions, Brucellosis and other medical and investigative practices.

! IMPORTANT NOTE: The only known compound whose anti-tumoral effects extends from the site of intralesional application to the same pathways as the cancer, and so, it attacks in even the areas affected by metastasis. Effects visible at week 8, 12 or 16 (monitored 52 weeks). Dose (average age: 70 years): from 0.1ml to 15ml, 1 to 4 times in humans.

Sources:

Mark B. Faries. (2017) "Intralesional Immunotherapy for Metastatic Melanoma: The Oldest and Newest Treatment in Oncology." Critical Reviews in Oncogenesis. PMCID: PMC5370206. NIHMSID: NIHMS850578. PMID: 27481003. doi: 10.1615/CritRevOncog.2016017124 - Intralesional Immunotherapy for Metastatic Melanoma: The Oldest and Newest Treatment in Oncology
*sobre Tratamiento Intralesional (por primera vez usado en 1891).
Extract: <<This dye was evaluated in a phase 2 study among 80 patients with refractory stage III and IV melanoma. The treatment yielded a 51% response rate, with half of the responses complete. Both injected and noninjected lesions were seen to regress and toxicity was quite limited, mainly consisting of injection site reaction.>>

Thompson JF, Hersey P, Wachter E. (2008) "Chemoablation of metastatic melanoma using intralesional Rose Bengal." Melanoma Research - Ovid Technologies. PMID: 18830132 doi: 10.1097/CMR.0b013e32831328c7. - Chemoablation of metastatic melanoma using intralesional Rose Bengal - PubMed
Extract: <<These findings indicate that intralesional Rose Bengal is nontoxic and could benefit patients with metastatic melanoma.>>

Paul Toomey, et al. (2013) "Intralesional Injection of Rose Bengal Induces a Systemic Tumor-Specific Immune Response in Murine Models of Melanoma and Breast Cancer". Intralesional Injection of Rose Bengal Induces a Systemic Tumor-Specific Immune Response in Murine Models of Melanoma and Breast Cancer - Intralesional Injection of Rose Bengal Induces a Systemic Tumor-Specific Immune Response in Murine Models of Melanoma and Breast Cancer
Extract: <<Treatment of the subcutaneous lesion with a single injection of IL PV-10 led to regression of the injected lesion as well as the distant B16 melanoma lung metastases.>>

Sanjiv S Agarwala (2012). "Intralesional therapy for metastatic melanoma with a focus on PV-10" Open Acess Journals - https://www.openaccessjournals.com/...metastatic-melanoma-with-a-focus-on-pv-10.pdf
Extract: In humans <<Among the subjects treated (49 male: 31 female; median age: 70 years [range:33–97years]), the median number of PV-10 treatments was two (range: 1–4), with a median dose per treatment of 1.6ml (0.1–15). Twenty four percent of patients had complete responses (CR) in target lesions and 25% had partial responses for an ORR of 49%. >>

Hao Liu, et al. (2016) "Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1". Oncotarget. PMID: 27177220. PMCID: PMC5122358. doi: 10.18632/oncotarget.9247. - https://www.ncbi.nlm.nih.gov/pubmed/27177220

Ajay V Maker, Bellur Prabhakar, and Krunal Pardiwala.(2015) "The Potential of Intralesional Rose Bengal to Stimulate T-Cell Mediated Anti-Tumor Responses". Journal of Clinical & Cellular Immunology. PMCID: PMC4662376. NIHMSID: NIHMS732008. PMID: 26618054. doi: 10.4172/2155-9899.1000343 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662376/ (otras 21 fuentes citadas)

Update of phase III trials in 2015 by Provectus:
- http://www.provectusbio.com/pv-10-for-melanoma

Extras:
https://www.medicalnewstoday.com/articles/153024.php#1

https://www.quiminet.com/productos/rosa-bengala-16547147270/proveedores.htm

There's another good news: Bengal Rose is not the only thing you can use.
Actually, it's kind of ridiculous but a lot of the anti-tumoral agents are actually very easy to get, even in a grocery store. Full list below.
Additionally, the intralesional method makes it so you will need less quantity of a consumable for it to have an effect (as opposed to eating these same things. Which is recommended too, as support treatment, but never in the dosis that would kill the cancer. Because you'd sooner intoxicate the patient).

And another good news: Puncturing a tumor doesn't hurt.
Like you said, your cat isn't in pain. The tumor only hurts when it's pushing against something like organs (which may happen later). Actually, for that reason alone, you could literally do it right now, puncturing the tumor, to drain the excess blood accumulating and that alone would help your cat. Yes, she will loose blood but it's all cancerigenous so getting it out of her system isn't any worse than keeping it there.
(But if you try: of course, use a disinfected needle.)

Additional notes:
> The (only) pros of melanoma/skin cancer: it's out there in plain sight, so you can do the intralesional method of treatment yourself.
> The cons: melanoma grows crazy fast, as you yourself probably already notice. Apparently it's because oxygen helps tumors grow. This also means it's likely to metastasize. In that case the tincture route is an attractive option (but with a warning: see notes on turmeric).

(*) In all cases, respect the maximum dose tolerated by the body. (Dosis at the end of document.)

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Anti-Tumoral Agents alternatives

Here's a few commonly found, affordable anti-tumoral elements you can buy easily at stores.

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- Olive Oil Extra Virgin:
Active principle: Oleocanthal, Maslinic [kills astrocytes]
(Extra: also analgestic, antioxidant, antiinflammatory)

Note:
* Targets the enzimes within the tumor, while healthy cells go into sleep momentarily, with no harm to the organism. Efects start to be visible within the first 30 minutes to two hours.
* Safe for cats.
* To keep in mind: olive oil -and any oil in general- is more dense than tinctures. So it will kill the tumor 'in situ' (at location) but not the places it has metastizied to.

Sources:

Onica LeGendre, Paul As Breslin, David A Foster (2015) "(-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization." Molecular and Cellular Oncology. doi: 10.1080/23723556.2015.1006077 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568762/

Goren L, Zhang G, Kaushik S, Breslin PAS, Du YN, Foster DA (2019) "(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells." Public Library of Science. DOI: 10.1371/journal.pone.0216024. PMID: 31412041. PMCID: PMC6693737 - https://www.ncbi.nlm.nih.gov/pubmed/31412041
Extract: <<(-)-Oleocanthal (oleocanthal) is a phenolic compound found in varying concentrations in extra virgin olive oil (...) Recently, we and other groups have demonstrated its specific and selective toxicity toward cancer cells; however, the mechanism leading to cancer cell death is still disputed. The current study demonstrates that oleocanthal, as well as naturally oleocanthal-rich extra virgin olive oils, induced damage to cancer cells' lysosomes leading to cellular toxicity in vitro and in vivo>>

Ruzzolini J, Peppicelli S, Andreucci E, Bianchini F, Scardigli A, Romani A, la Marca G, Nediani C, Calorini L. (2018) "Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies." Multidisciplinary Digital Publishing Institute (MDPI). pii: E1950. doi: 10.3390/nu10121950. PMID: 30544808 - https://www.ncbi.nlm.nih.gov/pubmed/30544808

Sotiroudis TG, Kyrtopoulos SA. (2008) "Anticarcinogenic compounds of olive oil and related biomarkers." European Journal of Nutrition, Suppl 2:69-72. doi: 10.1007/s00394-008-2008-9. Review. PMID: 18458836 - https://www.ncbi.nlm.nih.gov/pubmed/18458836

RW Owen, A Giacosa, WE Hull, R Haubner, B Spiegelhalder, H Bartsch (2000). "The antioxidant/anticancer potential of phenolic compounds isolated from olive oil". European Journal of Cancer. 36 (10): 1235–1247. doi:10.1016/S0959-8049(00)00103-9. PMID 10882862. - https://www.ncbi.nlm.nih.gov/pubmed/10882862

García-Villalba R, Carrasco-Pancorbo A, Oliveras-Ferraros C, Vázquez-Martín A, Menéndez JA, Segura-Carretero A, Fernández-Gutiérrez A. (2009/2010) "Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method." Epub / J Pharm Biomed Anal. doi: 10.1016/j.jpba. PMID: 19596535 - https://www.ncbi.nlm.nih.gov/pubmed/19596535

De Stefanis D, Scimè S, Accomazzo S, Catti A, Occhipinti A, Bertea CM, Costelli P. (2019) "Anti-Proliferative Effects of an Extra-Virgin Olive Oil Extract Enriched in Ligstroside Aglycone and Oleocanthal on Human Liver Cancer Cell Lines." Cancers — Open Access Journal by MDPI [Irish Association for Cancer Research (IACR)]. pii: E1640. doi: 10.3390/cancers11111640. PMID: 31653043 - https://www.ncbi.nlm.nih.gov/pubmed/31653043

Khanal P, Oh WK, Yun HJ, Namgoong GM, Ahn SG, Kwon SM, Choi HK, Choi HS. (2011) "p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis." Carcinogenesis. doi: 10.1093/carcin/bgr001. - https://www.ncbi.nlm.nih.gov/pubmed/21216846

Leite MS, Pacheco P, Gomes RN, Guedes AT, Castro-Faria-Neto HC, Bozza PT, Koatz VL. (2005) "Mechanisms of increased survival after lipopolysaccharide-induced endotoxic shock in mice consuming olive oil-enriched diet." The Shock Society. PMID: 15665734 - https://www.ncbi.nlm.nih.gov/pubmed/15665734

MORE: https://www.ncbi.nlm.nih.gov/pubmed/?term=virgin+olive+oil+tumor (PubMed: US National Library of Medicine National Institutes of Health)

https://scholar.google.com.ar/scholar?q=oleocanthal+renal+cancer&amp%3Bhl=es&amp%3Bas_sdt=0&amp%3Bas_vis=1&amp%3Boi=scholart#d=gs_qabs&u=%23p%3D28iVBqE_DTUJ

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- Turmeric
Active Principle: Curcumin
(Extra: also anti-inflammatory, anti-microbial / fungal, antioxidant, digestive, expectorant, hepatoprotective)

Note:
* One of the most powerful anti-tumoral agents (see sources).
* Safe for cats in the right dosis (see dosis later).
* Sold as tincture so it can be used as replacement for Bengal Rose (for it's wonderful effects on metastatic (4-stage) cancer: reducing the secondary tumors).
Warning: Cats are not very tolerable to alcohol. And any kind of tincture has at least some gradiation of it. Proceed with caution.
* Extra note: Because it's also a poweful anti-microbial, it helps to apply turmeric over wounds on the tumor, to keep it disinfected. Specially since it is close to the mouth and in contact with the food the cat eats. An infection on a tumor grows within and, when that happens, it's near impossible to kill with anti-biotics, oral or injected, so keeping it from getting infected is no small thing. Strongely recommended: After each meal (and each intralesional injection), apply turmeric powder on tumor topically.

Fuentes:

Gökçe Kütük S, Gökçe G, Kütük M, Gürses Cila HE, Naziroglu M. (2019) "Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress." Nature, Sci Rep. 2019 Nov 28;9(1):17784. doi: 10.1038/s41598-019-54284-x. PMID: 31780732 - https://www.ncbi.nlm.nih.gov/pubmed/31780732

Wang L, et al. (2019) "Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer." Journal of Experimental & Clinical Cancer Research. doi: 10.1186/s13046-019-1424-4. PMID: 31703744 - https://www.ncbi.nlm.nih.gov/pubmed/31703744

Almutairi FM, El Rabey HA, Tayel AA, Alalawy AI, Al-Duais MA, Sakran MI, Zidan NS. (2019) "Augmented anticancer activity of curcumin loaded fungal chitosan nanoparticles." International Journal of Biological Macromolecules. pii: S0141-8130(19)38909-3. doi: 10.1016/j.ijbiomac.2019.11.207. PMID: 31786303 - https://www.ncbi.nlm.nih.gov/pubmed/31786303

Masashi Kanai, et al. (2013) "A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients." Cancer Chemotherapy and Pharmacology. PMID:23543271 doi: 10.1007/s00280-013-2151-8. - https://www.ncbi.nlm.nih.gov/pubmed/23543271

Dhillon N, Aggarwal BB, Newman RA, Wolff RA, Kunnumakkara AB, Abbruzzese JL, Ng CS, Badmaev V, Kurzrock R. (2008) "Phase II trial of curcumin in patients with advanced pancreatic cancer." American Association for Cancer Research. PMID: 18628464. doi: 10.1158/1078-0432.CCR-08-0024. - https://www.ncbi.nlm.nih.gov/pubmed/18628464

Andrés Hernán Cardona Echeverry,I Diego Fernando Uribe Yunda,I,II Fabian Mauricio Cortés-Mancera. (2016) "Actividad antitumoral de la curcumina asociada a la regulación de mecanismos epigenéticos: implicaciones en la vía Wnt/-catenina." [Translation: "Anti-tumor activity of curcumin associated with the regulation of epigenetic mechanisms: implications in the Wnt / -catenin pathway." ] Revista Cubana de Plantas Medicinales / Elsevier. EID: 2-s2.0-85026836271 - http://scielo.sld.cu/pdf/pla/v21n4/pla13416 (article provides 71 sources)

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=tumor+curcumin (note: web search in the US National Library of Medicine gave 256 pages of results)

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- Broccoli
Active Principle: Sulforaphane (isothiocyanate (methylsulfinyl) -butane), indole-3-carbinol, glucosinolates.
(Extra: also antioxidant, anti-inflammatory, protects bones / heart / eyes / skin and helps with anemia. Sulforaphane is also protective against toxicity. Broccoli has complex hepatic action.)

Notes on dosis: 2.7 kilos of broccoli are needed per day -supplied orally- to affect the tumor in humans, when 30gr is the recommended consumption limit. > Non-viable as diet alone. There are 0.25ml sulforaphane per 100gr of broccoli. (67.5ml / gr sulforaphane in 2.7kilos > 67.5gr sulforaphane is the amount that kills tumors in humans.) Hence: recommended intralesionally, through tincture or powder disolved in water. (See dosis at the end of the document.)

Sources:

Cierpial T, Kielbasinski P, Kwiatkowska M, Lyzwa P, Lubelska K, Kuran D, Dabrowska A, Kruszewska H, Mielczarek L, Chilmonczyk Z, Wiktorska K. (2019) "Fluoroaryl analogs of sulforaphane - A group of compounds of anticancer and antimicrobial activity." Bioorg Chem. doi: 10.1016/j.bioorg.2019.103454. PMID: 31787344

Tomczyk J, Olejnik A. (2010) "Sulforaphane--a possible agent in prevention and therapy of cancer." Index Copernicus International. PMID: 21160094 - https://phmd.pl/resources/html/article/details?id=8221&language=en (* Only in this link there are 104 bibliography sources with their respective links and publication data.)

Llee YR, et al. (2019) "Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway." Science. DOI: 10.1126/science.aau0159 - https://science.sciencemag.org/content/364/6441/eaau0159 (Artículo en español: https://genotipia.com/genetica_medica_news/brocoli-cancer/)

Clarke JD, Dashwood RH, Ho E. (2008) "Multi-targeted prevention of cancer by sulforaphane." PMID: 18504070. PMCID: PMC2579766. DOI: 10.1016/j.canlet.2008.04.018 - https://www.ncbi.nlm.nih.gov/pubmed/18504070
Extract: <<Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables and is especially high in broccoli and broccoli sprouts. (...) This review discusses the established anti-cancer properties of SFN, with an emphasis on the possible chemoprevention mechanisms. The current status of SFN in human clinical trials also is included, with consideration of the chemistry, metabolism, absorption and factors influencing SFN bioavailability.>>

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=sulforaphane+cancer

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- Rosemary
Active Principle: Polyphenols, carnosic acid, carnosol and betulinic acid
(Extra: also analgesic, anti-inflammatory, antiseptic, antioxidant and scar-healing)

Sources:

[SPANISH-ENGLISH] Almudena Pérez Sánchez. (2017) “Actividad antitumoral de un extracto de romero (Rosmarinus officinalis L.) en modelos in vitro e in vivo de cáncer de colon.” Tesis en acceso abierto en RediUMH (Universidad Miguel Hernández, España) - http://dspace.umh.es/handle/11000/3619
Extracto: <<El objetivo del presente trabajo ha sido determinar la actividad antitumoral de un extracto de romero (ER) enriquecido en terpenoides en modelos in vitro e in vivo de cáncer colorrectal humano (...) La capacidad antiproliferativa del extracto ha sido corroborada en un modelo animal de xenotransplantes humanos de cáncer de colon y se ha verificado en ratas su ausencia de toxicidad a los niveles máximos permitidos por la regulación existente relativa a ensayos animales.>>
[Translation: <<The objective of this work has been to determine the antitumor activity of a terpenoid-enriched rosemary extract (ER) in in vitro and in vivo models of human colorectal cancer (...) The antiproliferative capacity of the extract has been corroborated in an animal model of colon cancer human xenotransplantation and its absence of toxicity has been verified in rats at the maximum levels allowed by the existing regulation related to animal tests.>>]

Pérez-Sánchez A, Barrajón-Catalán E, Ruiz-Torres V, Agulló-Chazarra L, Herranz-López M, Valdés A, Cifuentes A, Micol V. (2019). "Rosemary (Rosmarinus officinalis) extract causes ROS-induced necrotic cell death and inhibits tumor growth in vivo." Nature / Sci Rep. doi: 10.1038/s41598-018-37173-7. PMID: 30692565 - https://www.ncbi.nlm.nih.gov/pubmed/30692565

Cattaneo L, Cicconi R, Mignogna G, Giorgi A, Mattei M, Graziani G, Ferracane R, Grosso A, Aducci P, Schininà ME, Marra M. (2015) "Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells." Public Library of Science. doi: 10.1371/journal.pone.0132439. - https://www.ncbi.nlm.nih.gov/pubmed/26176704

Shuai Han, Xin Li, Yun Xia, Zhengsen Yu, Ningning Cai, Satish R. Malwal, Xu Han, Eric Oldfield, Yonghui Zhang. (2019) "Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells." J. Med. Chem. American Chemical Society. PMID: 31725297. DOI: 10.1021/acs.jmedchem.9b01405 - https://www.ncbi.nlm.nih.gov/pubmed/31725297
Extract: <<Here, we report the discovery and development of HsFPPS inhibitors based on the phenolic diterpene carnosic acid (CA), an antimicrobial found in rosemary and sage, which showed better cellular anticancer activities than the bisphosphonate drug zoledronate in pancreatic cancer cell lines, as well as an HsFPPS-dependent mechanism of action.>>

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- Oregano
Active Principle: Carvacrol, Thymol
(Extra: also anti-inflammatory, analgesic, antioxidant, antiseptic / antimicrobial / antibacterial, effective topically for infections)

Sources:

Benhalilou Nehla, et al. (2019) "Origanum majorana Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway." Frontiers in Oncology. PMID: 31497536. PMCID: PMC6712482. doi: 10.3389/fonc.2019.00795. - https://www.ncbi.nlm.nih.gov/pubmed/31497536

Peter Kubatka, et al. (2017) "Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model." European Journal of Nutrition. PMID: 26907089. doi: 10.1007/s00394-016-1181-5. - https://www.ncbi.nlm.nih.gov/pubmed/26907089

Balusamy SR, Perumalsamy H, Huq MA, Balasubramanian B. (2018) "Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines." Biomedicine & Pharmacotherapy, Elsevier Masson. - PMID: 30372889. doi: 10.1016/j.biopha.2018.10.028. https://www.ncbi.nlm.nih.gov/pubmed/30372889

Li Wang et al. (2018) "Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2." Oncotarget. PMID: 30344937. PMCID: PMC6188138. doi: 10.18632/oncotarget.24409 - https://www.ncbi.nlm.nih.gov/pubmed/30344937

Whasun Lim, Jiyeon Ham, Fuller W. Bazer, Gwonhwa Song (2018) "Carvacrol induces mitochondria-mediated apoptosis via disruption of calcium homeostasis in human choriocarcinoma cells." Journal of Cellular Physiology. PMID: 30070691. doi: 10.1002/jcp.27054. - https://www.ncbi.nlm.nih.gov/pubmed/30070691

Jorge J. De La Chapa, Prajjal Kanti Singha, Debbie R. Lee, Cara B. Gonzales (2018) "Thymol inhibits oral squamous cell carcinoma growth via mitochondria-mediated apoptosis." Journal of Oral Pathology and Medicine. PMCID: PMC6105452. DOI: 10.1111/jop.12735 - https://www.ncbi.nlm.nih.gov/pubmed/29777637

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Following is an additional list of consumables with known and proven anti-tumoral effects.

Parsley
Active Principle: apigenina

Plum / Peach
Active Principle: anthocyanins (cyanidin-3-glucoside), carotenoids, phenolics (chlorogenic acid and glycosides) (*note: another that kills cancerous cells without damaging healthy cells)
Warning: some sources say not safe for cats

Watercress
Active Principle: isotiocianato de feniletilo (PEITC) [MEITC also recommended]

Seaweed [Mozuku (Cladosiphon okamuranus), Mekabu (part of Wakame) and Kombu (Laminaria japonica) and Hondawara]
Active Principle: fucoidan (* contraindications: high iodine and salt content)

Garlic
Active Principle: diallyl disulfide (+ lysine and quercetin)
Warning: not safe for cats.

Green Tea
Active Principle: EGCG

Blueberries and other berries
Active Principle: flavonoids and anthocyanins [antioxidant polyphenolic; grapes / peanuts: resveratrol; blackberry / raspberry: anthocyanins]
Warning: some berries not safe for cats.

Tomatoes
Active Principle: licopeno, oligosacarias (https://www.sciencedirect.com/science/article/pii/S0144861716314138)

Grenade
Active Principle: polyphenols (flavonoids and tannins), ellagic acid and punicalagin(https://www.hindawi.com/journals/ecam/2015/258598/ + chart https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560105/)
Warning: not safe for cats

Apple
Active Principle: fitoquímicos

Walnuts
Active Principle: fitosteroles

Yogurt
Active Principle: "bacterias buenas" del yogurt

Coffee (topic use)
Active Principle: caffeine (inhibits damaged ATR proteins)

Flax seeds
Active Principle: alpha-linolenic acid (omega-3); lignans (phytoestrogens and antioxidants) and dietary fiber

Carrot, Sweet Potatoes
Active Principle: beta-carotene and tocopherol

Pumpkin
Active Principle: carotenoids (alpha-carotene, beta-carotene, lycopene, lutein, cryptoxanthin)

Spinach / chard / lettuce
Active Principle: 13 different flavonoid compounds

Onion
Active Principle: onionin A
Warning: not safe for cats

Brewer's yeast
Active Principle: synthetic RNA oligonucleotides

Soy / Tofu
Active Principle: Genistein

Milk*
Active Principle: TRAIL, vitamin C and “Hamlet”. (* Warning: also contain casein = carcinogenic)
Warning: most cats are intolerable

Omega 3 foods*
Active Principle: resolvin, docosahexaenoic acid, eicosapentaenoic acid (against sarcopenia / cachexia), n-3 PUFAs (anti-inflammatories. * Note: some studies says may cause cancer)
https://www.ncbi.nlm.nih.gov/pubmed/30009833
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728677/
https://www.ncbi.nlm.nih.gov/pubmed/17640164
https://www.bmj.com/content/bmj/4/5883/1.1.full.pdf

Mushrooms* (e.g.shiitake, maitake, reishi, etc)
https://www.cancer.gov/espanol/cancer/tratamiento/mca/paciente/hongos-pdq
https://www.gacetamedica.com/especi...ra-nuevos-farmacos-contra-el-cancer-FF1689007

(*) Foods that merely <prevent> cancer were not included in this list. Only foods to <treat> post-diagnosis cancer (which may or may not also be preventive) were included.

ALSO OF NOTE:
* promoters of NK cells (Natural Killers, attack tumors) : carotenoids, vitamin E
* promoters of helper Tcells : CD4 + CD25 + Foxp3 + Tregs in PP, carotenoids

ALSO OF NOTE:
Opposing research : articles that speaks against antioxidants in cancer patients:
https://www.scientificamerican.com/...xidantes-mas-bien-podrian-empeorar-el-cancer/
https://www.cancer.gov/espanol/noticias/temas-y-relatos-blog/2015/antioxidantes-metastasis

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ABOUT USING THE LIST AS DIET (keywords: herbal medicine, fitotheraphy, diet therapy)
Cancer diet note: relatively low in simple sugars, moderate amounts of highly bioavailable or high biological value proteins (white meat, fish, milk, cheese, yogurt), increased fiber (spinach, broccoli) and moderate amounts of polyunsaturated fatty acids n- 3 (fish, shellfish) but avoid PUFA amino acids.

Anecdotical experience of cat owner keeping the cancer in her cat at bay using diet -links:
https://smoda.elpais.com/belleza/mi-cura-del-cancer-fue-un-milagro-muy-currado/ (fitothery experience [spanish])

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NON-FOOD/CONDIMENT TREATMENTS OF NOTE

* Salinomycin / salinomicina (antibiotic for poultry, discovered to be highly effective)
https://www.nature.com/articles/nchem.2778

About Salinomycin (trade name: Cassab Feed Microline, Bovisacc)
Description: antibiotic for poultry.
Active Principle: ionophore (coccidiostacts)
Contraindication: can cause hypocalcemia and leukocytes

Sources:

Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, Zhang J, Pan J. (2019) "Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma." Molecular Cancer. PMID: 31718679. PMCID: PMC6852970. DOI: 10.1186/s12943-019-1068-1 - https://www.ncbi.nlm.nih.gov/pubmed/31718679

Czerwonka D, Urbaniak A, Sobczak S, Piña-Oviedo S, Chambers TC, Antoszczak M, Huczynski A. (2019) "Synthesis and Anticancer Activity of Tertiary Amides of Salinomycin and Their C20-oxo Analogues." ChemMedChem. PMID: 31702860. doi: 10.1002/cmdc.201900593. - https://www.ncbi.nlm.nih.gov/pubmed/31702860

Novohradsky V, Markova L, Kostrhunova H, Trávnícek Z, Brabec V, Kasparkova J. (2019) "An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis." Nature. doi: 10.1038/s41598-019-49774-x. - https://www.ncbi.nlm.nih.gov/pubmed/31527683

Zhongyuan Wang, et al. (2019) "Salinomycin exerts anti-colorectal cancer activity by targeting the ß-catenin/T-cell factor complex." British Journal of Pharmacology. PMID: 31236922. PMCID: PMC6692576. doi: 10.1111/bph.14770. - https://www.ncbi.nlm.nih.gov/pubmed/31236922

Hero T, Bühler H, Kouam PN, Priesch-Grzeszowiak B, Lateit T, Adamietz IA. (2019) "The Triple-negative Breast Cancer Cell Line MDA-MB 231 Is Specifically Inhibited by the Ionophore Salinomycin." Anticancer Research. PMID: 31177119. doi: 10.21873/anticanres. - https://www.ncbi.nlm.nih.gov/pubmed/31177119

Otro: https://www.elmundo.es/elmundosalud/2009/08/14/oncologia/1250228714.html

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=salinomycin+tumor
https://www.nature.com/articles/nchem.2778

-----------------------------------

* Legasil (food supplement for liver problems based on sea thistle. Active Principle: silibinin)

(*) About Legasil (marine thistle molecule. Active Principle: silibinin)
[English Translation: << the case of a 39-year-old patient with breast cancer and bone and liver metastases, who came to her office in 2014. The woman did not respond to chemotherapy - with paclitaxel from Pacific yew - and the doctors gave her barely a month of life. Given his liver problems, Bosch prescribed Legasil, a milk thistle-based food supplement marketed as a liver protector. Unexpectedly, the patient reacted and survived 20 months.
(...) The pharmaceutical companies consulted have refused to participate, "perhaps for fear of not recovering the investment," according to Bosch. The treatment with Legasil that they have used this time costs about 100 euros a month, compared to the usual thousands of euros in cancer drugs]

[Original: <<el caso de una paciente de 39 años con cáncer de mama y metástasis en hueso e hígado, que llegó a su consulta en 2014. La mujer no respondía a la quimioterapia —con el paclitaxel del tejo del Pacífico— y los médicos le daban apenas un mes de vida. Dados sus problemas en el hígado, Bosch le indicó Legasil, un complemento alimenticio a base de cardo mariano, comercializado como protector hepático. Inesperadamente, la paciente reaccionó y sobrevivió 20 meses.
(...) Las farmacéuticas a las que han llamado a la puerta han rechazado participar, “quizá por temor a no recuperar la inversión”, según Bosch. El tratamiento con Legasil que han empleado esta vez cuesta unos 100 euros al mes, frente a los miles de euros habituales en los fármacos oncológicos>>]

https://elpais.com/elpais/2018/06/11/ciencia/1528727883_239077.html

Sources:

Bosch-Barrera J, et al.
- "Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin." (2016) Oncotarget. doi: 10.18632/oncotarget.7900. PMID: 26959886
https://www.ncbi.nlm.nih.gov/pubmed/26959886
- "Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy." (2015) Cancer Treatment Reviews. doi: 10.1016/j.ctrv.2015.04.008. PMID: 25944486
https://www.ncbi.nlm.nih.gov/pubmed/25944486
- "Targeting STAT3 with silibinin to improve cancer therapeutics." (2017) Cancer Treatment Reviews. doi: 10.1016/j.ctrv.2017.06.003. PMID: 28686955
https://www.ncbi.nlm.nih.gov/pubmed/28686955
- "Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient." (2014) Anticancer Research: Internacional Journal of Cancer Research and Treatment (by The International Institute of Anticancer Research). PMID: 25075066
http://ar.iiarjournals.org/content/34/8/4323.long

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Own notes (Rey, Nadia I.):

My experience was with a metastatic oral melanoma in a cat. The elements used were the first six (Olive Oil, Oregano, Rosemary, Turmeric, Broccoli and Rose Bengal), topically or intralesionally, with occasional use of other elements such as spinach and watercress (used to counteract the anticoagulant effect of the other elements). [Items like plum and garlic ruled out for toxicity in cats.]

The effects were seen within a few hours. In 24 hours, it left a hole in the affected gum that reached the jaw bone, without damaging healthy tissue and without causing pain. The continued use of these elements in a topical / intralesional way reduced the paralysis in the tongue and allowed her to eat, at the same time that their antibiotic properties kept the area disinfected (a cleaning and reapplication process was carried out after each meal).

At the same time, the taking of three syrups that functioned as adjuvants of a veterinary immunotherapeutic treatment developed with molecules of turmeric, blueberry and other elements mentioned, developped by the Veterinary Immunotherapeutic Center (CIV) in Buenos Aires, improved her mood immensely - and therefore her quality of life. .

The discovery of the antitumoral effect of these elements was accidental: it was applied topically because the analgesic effect of these natural elements was sought to avoid the use of corticosteroids, because the kidney was affected as a result of three surgeries. Following this, this list was researched online and compiled. It may be incomplete.

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* Reference data for topical / intralesional application in cancer diagnosis (melanoma):

Formula (dose) in humans:
Olive oil 50ml per day (recommended consumption limit).
Broccoli 30 to 60gr per day (recommended consumption limit).
Turmeric and oregano 6gr (recommended limit in plant intake) or 10 drops per day in essential oil.
Rosemary 10gr (recommended limit in plant intake) or 10 drops per day in essential oil.
Rose Bengal 0.1ml to 15ml, 1 to 4 times total treatment.

Formula in cats:
Aceite oliva 1,5ml
Brócoli 1gr
Curcuma y oregano 0,2gr
Romero 1/2 gota
Rose Bengala 1,4ml

(*) Amounts may vary according to the weight of the patient. These are the minimal references.

Contact information:
@ Nadia Irene Rey (2019)
[email protected]
54 9 341 (15)3265069

Caannes · Mar 21, 2022

If it were me I’d ask the vet for cleaning recommendations—I’m wondering if a gauze pad or washcloth with warm water/saline as a gentle compress to loosen dried food, then gently rinsed with a syringe of warm water. Preferably slowly and gently while petting with her head on a towel in your lap, because it’s important above all she’s not feeling tortured

I’m sorry for the diagnosis

NadiaRey · Mar 21, 2022

I wanted to share one last thing. These are photos of the how the tumor in my cat looked when it was fully grown (She had three surgeries, and each time the tumor grew again, or bigger. Also the white things: it got infected because of the first surgery.)

... and after I used the intralesional method.

The teeth were already yellow from decay because this was three months in.

They told me Sueño shouldn't have lasted a month. She lasted five. And it was only because the third sugery opened bloodvesels to the back of the throat, making the cancer spread and her unable to drink water, that we decided to her go. Otherwise, she was looking unbelievable strong. Specially considering she was 18 years old. She was even putting on weight. She was a fighter.

*

Sorry I just went on a rant about my experience or oversharing. I thought maybe you would need more context.

I'm not gonna lie, I was fearfully enamoured with the idea of the Intralesional Treatment reaching even the place where the cancer had spread. It kind of blows my mind this info isn't shared widely. Bengal Rose tincture seems to be the only known thing that treats metastatic (4-stage) cancer, without the toxicity of chemotheraphy.

I also want to make clear I'm not a doctor or vet or medical researcher, I just read research others did. As per shown up there.

And keep in mind I didn't get the ok from the vets. (How could they okay it? It hasn't even been cleared for humans, to okay it would be to malpractice.)

But that is not to say it's in itself unsafe. What would be unsafe is to not respect the dosis, which I drafted using as reference what has been done with humans and what was used safely in rats before them, as per my cat's weight.

It's kind of promising a miracle. I know that's irresponsible. But, though I only have Sueño experience as reference, I can tell at least I didn't hurt her with this.

And it's not possible for me to promise it will work for you for sure, but of course I'll at least give you the data.

Best of luck.

Sherrybaby77 · Apr 3, 2022

Sherrybaby77 said:
Hi,
I have an 18 year old cat that has a cancerous growth on her chin. She has been to the vet, and animal dermatologist. I have been told it’s cancer and it can not be removed because she has a heart murmur and high blood pressure which she is on medication for. If I put her under the vet said there is a high chance she won’t wake up. I have no choice but to leave it alone.
She still eats and drinks on her own, is not in pain, but her food gets stuck on the growth and I have to clean it which irritates it. I feel horrible not doing anything as it gets bigger and I don’t know what else I can do to help her. She isn’t suffering. Any suggestions would be helpful. I have attached a picture of the growth…just a warning is not a pretty growth.

FeebysOwner said:
Hi. I really don't have any great ideas on how to keep that clean, but you could try to use chamomile tea bags. You can buy them at most any grocery store as those are usually German (you don't want English, or any flavorings or additives). Brew a bag in water, cool the liquid to room temp, and then just use cotton balls to dab the liquid on that growth. Hopefully, just the 'dabbng' action will remove most of the food. No need to wipe it off, as it is safe for your cat to ingest. The tea has soothing and healing properties and is considered an anti-bacterial/anti-fungal agent as well.

Thank you so much for your reply…will try the tea bags!!

Sherrybaby77 · Apr 3, 2022

fionasmom said:
I had a 17 year old cat who developed something that looked almost identical with the exception of the fact that it was growing out of her ear. The vet flat out refused to operate because of her age and other conditions...and I would probably not have done the surgery regardless.

The chamomile tea bags are an excellent idea. Basically, don't use anything that could sting or burn, even if you think that it is cleaning the lesion. If she will let you hold a moist teabag next to it in order to loosen the food, it will come off easier.

Thank you for your reply and agreeing with the tea bags…going to try that!!

Sherrybaby77 · Apr 3, 2022

NadiaRey said:
I think I can help. This is exactly what my cat Sueño had. Back when she had a few weeks to live, I went and did a lot of research, and came up with a homemade treatment that I wished I had months before that. And I often think if I had another chance, I would do a lot of things differently. So here's what I'd do with what I know now (and what I kind of did).

I'll give you all the relevant information I gathered.
Please read everything before you try anything.

Method: Intralesional Treatment.
Intralesional Immunotherapy for Metastatic Melanoma: The Oldest and Newest Treatment in Oncology

Background: So, back during a test for a cancer treatment using lasers, they painted the tumor with a contrast tincture used commonly in medicine, so they could check how was the size of the tumor before and after using the laser. Well, it turns out the tumor started dying from the tincture alone, even before they used the laser. That's how, purely by accident, they discovered that the Bengal Rose tincture was a powerful anti-tumoral.
And also, that you can kill a tumor more efficiently by injecting it directly with an anti-tumoral agent.

So, yes, I'm telling you there's a treatment where you yourself can inject something to a tumor to kill it.

There's another good news: Bengal Rose is not the only thing you can use.
Actually, it's kind of ridiculous but a lot of the anti-tumoral agents are actually very easy to get, even in a grocery store. Full list below.
Additionally, the intralesional method makes it so you will need less quantity of a consumable for it to have an effect (as opposed to eating these same things. Which is recommended too, as support treatment, but never in the dosis that would kill the cancer. Because you'd sooner intoxicate the patient).

And another good news: Puncturing a tumor doesn't hurt.
Like you said, your cat isn't in pain. The tumor only hurts when it's pushing against something like organs (which may happen later). Actually, for that reason alone, you could literally do it right now, puncturing the tumor, to drain the excess blood accumulating and that alone would help your cat. Yes, she will loose blood but it's all cancerigenous so getting it out of her system isn't any worse than keeping it there.
(But if you try: of course, use a disinfected needle.)

Additional notes:
> The (only) pros of melanoma/skin cancer: it's out there in plain sight, so you can do the intralesional method of treatment yourself.
> The cons: melanoma grows crazy fast, as you yourself probably already notice. Apparently it's because oxygen helps tumors grow. This also means it's likely to metastasize. In that case the tincture route is an attractive option (but with a warning: see notes on turmeric).

(*) In all cases, respect the maximum dose tolerated by the body. (Dosis at the end of document.)

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Anti-Tumoral Agents alternatives

Here's a few commonly found, affordable anti-tumoral elements you can buy easily at stores.

------------------------------------------------------------

- Olive Oil Extra Virgin:
Active principle: Oleocanthal, Maslinic [kills astrocytes]
(Extra: also analgestic, antioxidant, antiinflammatory)

Note:
* Targets the enzimes within the tumor, while healthy cells go into sleep momentarily, with no harm to the organism. Efects start to be visible within the first 30 minutes to two hours.
* Safe for cats.
* To keep in mind: olive oil -and any oil in general- is more dense than tinctures. So it will kill the tumor 'in situ' (at location) but not the places it has metastizied to.

Sources:

Onica LeGendre, Paul As Breslin, David A Foster (2015) "(-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization." Molecular and Cellular Oncology. doi: 10.1080/23723556.2015.1006077 - (-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization

Goren L, Zhang G, Kaushik S, Breslin PAS, Du YN, Foster DA (2019) "(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells." Public Library of Science. DOI: 10.1371/journal.pone.0216024. PMID: 31412041. PMCID: PMC6693737 - (-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells - PubMed
Extract: <<(-)-Oleocanthal (oleocanthal) is a phenolic compound found in varying concentrations in extra virgin olive oil (...) Recently, we and other groups have demonstrated its specific and selective toxicity toward cancer cells; however, the mechanism leading to cancer cell death is still disputed. The current study demonstrates that oleocanthal, as well as naturally oleocanthal-rich extra virgin olive oils, induced damage to cancer cells' lysosomes leading to cellular toxicity in vitro and in vivo>>

Ruzzolini J, Peppicelli S, Andreucci E, Bianchini F, Scardigli A, Romani A, la Marca G, Nediani C, Calorini L. (2018) "Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies." Multidisciplinary Digital Publishing Institute (MDPI). pii: E1950. doi: 10.3390/nu10121950. PMID: 30544808 - Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies - PubMed

Sotiroudis TG, Kyrtopoulos SA. (2008) "Anticarcinogenic compounds of olive oil and related biomarkers." European Journal of Nutrition, Suppl 2:69-72. doi: 10.1007/s00394-008-2008-9. Review. PMID: 18458836 - Anticarcinogenic compounds of olive oil and related biomarkers - PubMed

RW Owen, A Giacosa, WE Hull, R Haubner, B Spiegelhalder, H Bartsch (2000). "The antioxidant/anticancer potential of phenolic compounds isolated from olive oil". European Journal of Cancer. 36 (10): 1235–1247. doi:10.1016/S0959-8049(00)00103-9. PMID 10882862. - The antioxidant/anticancer potential of phenolic compounds isolated from olive oil - PubMed

García-Villalba R, Carrasco-Pancorbo A, Oliveras-Ferraros C, Vázquez-Martín A, Menéndez JA, Segura-Carretero A, Fernández-Gutiérrez A. (2009/2010) "Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method." Epub / J Pharm Biomed Anal. doi: 10.1016/j.jpba. PMID: 19596535 - Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method - PubMed

De Stefanis D, Scimè S, Accomazzo S, Catti A, Occhipinti A, Bertea CM, Costelli P. (2019) "Anti-Proliferative Effects of an Extra-Virgin Olive Oil Extract Enriched in Ligstroside Aglycone and Oleocanthal on Human Liver Cancer Cell Lines." Cancers — Open Access Journal by MDPI [Irish Association for Cancer Research (IACR)]. pii: E1640. doi: 10.3390/cancers11111640. PMID: 31653043 - Anti-Proliferative Effects of an Extra-Virgin Olive Oil Extract Enriched in Ligstroside Aglycone and Oleocanthal on Human Liver Cancer Cell Lines - PubMed

Khanal P, Oh WK, Yun HJ, Namgoong GM, Ahn SG, Kwon SM, Choi HK, Choi HS. (2011) "p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis." Carcinogenesis. doi: 10.1093/carcin/bgr001. - p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis - PubMed

Leite MS, Pacheco P, Gomes RN, Guedes AT, Castro-Faria-Neto HC, Bozza PT, Koatz VL. (2005) "Mechanisms of increased survival after lipopolysaccharide-induced endotoxic shock in mice consuming olive oil-enriched diet." The Shock Society. PMID: 15665734 - Mechanisms of increased survival after lipopolysaccharide-induced endotoxic shock in mice consuming olive oil-enriched diet - PubMed

MORE: virgin olive oil tumor - Search Results - PubMed (PubMed: US National Library of Medicine National Institutes of Health)

https://scholar.google.com.ar/scholar?q=oleocanthal+renal+cancer&amp%3Bhl=es&amp%3Bas_sdt=0&amp%3Bas_vis=1&amp%3Boi=scholart#d=gs_qabs&u=%23p%3D28iVBqE_DTUJ

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- Turmeric
Active Principle: Curcumin
(Extra: also anti-inflammatory, anti-microbial / fungal, antioxidant, digestive, expectorant, hepatoprotective)

Note:
* One of the most powerful anti-tumoral agents (see sources).
* Safe for cats in the right dosis (see dosis later).
* Sold as tincture so it can be used as replacement for Bengal Rose (for it's wonderful effects on metastatic (4-stage) cancer: reducing the secondary tumors).
Warning: Cats are not very tolerable to alcohol. And any kind of tincture has at least some gradiation of it. Proceed with caution.
* Extra note: Because it's also a poweful anti-microbial, it helps to apply turmeric over wounds on the tumor, to keep it disinfected. Specially since it is close to the mouth and in contact with the food the cat eats. An infection on a tumor grows within and, when that happens, it's near impossible to kill with anti-biotics, oral or injected, so keeping it from getting infected is no small thing. Strongely recommended: After each meal (and each intralesional injection), apply turmeric powder on tumor topically.

Fuentes:

Gökçe Kütük S, Gökçe G, Kütük M, Gürses Cila HE, Naziroglu M. (2019) "Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress." Nature, Sci Rep. 2019 Nov 28;9(1):17784. doi: 10.1038/s41598-019-54284-x. PMID: 31780732 - Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress - PubMed

Wang L, et al. (2019) "Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer." Journal of Experimental & Clinical Cancer Research. doi: 10.1186/s13046-019-1424-4. PMID: 31703744 - Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer - PubMed

Almutairi FM, El Rabey HA, Tayel AA, Alalawy AI, Al-Duais MA, Sakran MI, Zidan NS. (2019) "Augmented anticancer activity of curcumin loaded fungal chitosan nanoparticles." International Journal of Biological Macromolecules. pii: S0141-8130(19)38909-3. doi: 10.1016/j.ijbiomac.2019.11.207. PMID: 31786303 - https://www.ncbi.nlm.nih.gov/pubmed/31786303

Masashi Kanai, et al. (2013) "A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients." Cancer Chemotherapy and Pharmacology. PMID:23543271 doi: 10.1007/s00280-013-2151-8. - https://www.ncbi.nlm.nih.gov/pubmed/23543271

Dhillon N, Aggarwal BB, Newman RA, Wolff RA, Kunnumakkara AB, Abbruzzese JL, Ng CS, Badmaev V, Kurzrock R. (2008) "Phase II trial of curcumin in patients with advanced pancreatic cancer." American Association for Cancer Research. PMID: 18628464. doi: 10.1158/1078-0432.CCR-08-0024. - https://www.ncbi.nlm.nih.gov/pubmed/18628464

Andrés Hernán Cardona Echeverry,I Diego Fernando Uribe Yunda,I,II Fabian Mauricio Cortés-Mancera. (2016) "Actividad antitumoral de la curcumina asociada a la regulación de mecanismos epigenéticos: implicaciones en la vía Wnt/-catenina." [Translation: "Anti-tumor activity of curcumin associated with the regulation of epigenetic mechanisms: implications in the Wnt / -catenin pathway." ] Revista Cubana de Plantas Medicinales / Elsevier. EID: 2-s2.0-85026836271 - http://scielo.sld.cu/pdf/pla/v21n4/pla13416 (article provides 71 sources)

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=tumor+curcumin (note: web search in the US National Library of Medicine gave 256 pages of results)

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- Broccoli
Active Principle: Sulforaphane (isothiocyanate (methylsulfinyl) -butane), indole-3-carbinol, glucosinolates.
(Extra: also antioxidant, anti-inflammatory, protects bones / heart / eyes / skin and helps with anemia. Sulforaphane is also protective against toxicity. Broccoli has complex hepatic action.)

Notes on dosis: 2.7 kilos of broccoli are needed per day -supplied orally- to affect the tumor in humans, when 30gr is the recommended consumption limit. > Non-viable as diet alone. There are 0.25ml sulforaphane per 100gr of broccoli. (67.5ml / gr sulforaphane in 2.7kilos > 67.5gr sulforaphane is the amount that kills tumors in humans.) Hence: recommended intralesionally, through tincture or powder disolved in water. (See dosis at the end of the document.)

Sources:

Cierpial T, Kielbasinski P, Kwiatkowska M, Lyzwa P, Lubelska K, Kuran D, Dabrowska A, Kruszewska H, Mielczarek L, Chilmonczyk Z, Wiktorska K. (2019) "Fluoroaryl analogs of sulforaphane - A group of compounds of anticancer and antimicrobial activity." Bioorg Chem. doi: 10.1016/j.bioorg.2019.103454. PMID: 31787344

Tomczyk J, Olejnik A. (2010) "Sulforaphane--a possible agent in prevention and therapy of cancer." Index Copernicus International. PMID: 21160094 - https://phmd.pl/resources/html/article/details?id=8221&language=en (* Only in this link there are 104 bibliography sources with their respective links and publication data.)

Llee YR, et al. (2019) "Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway." Science. DOI: 10.1126/science.aau0159 - https://science.sciencemag.org/content/364/6441/eaau0159 (Artículo en español: https://genotipia.com/genetica_medica_news/brocoli-cancer/)

Clarke JD, Dashwood RH, Ho E. (2008) "Multi-targeted prevention of cancer by sulforaphane." PMID: 18504070. PMCID: PMC2579766. DOI: 10.1016/j.canlet.2008.04.018 - https://www.ncbi.nlm.nih.gov/pubmed/18504070
Extract: <<Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables and is especially high in broccoli and broccoli sprouts. (...) This review discusses the established anti-cancer properties of SFN, with an emphasis on the possible chemoprevention mechanisms. The current status of SFN in human clinical trials also is included, with consideration of the chemistry, metabolism, absorption and factors influencing SFN bioavailability.>>

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=sulforaphane+cancer

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- Rosemary
Active Principle: Polyphenols, carnosic acid, carnosol and betulinic acid
(Extra: also analgesic, anti-inflammatory, antiseptic, antioxidant and scar-healing)

Sources:

[SPANISH-ENGLISH] Almudena Pérez Sánchez. (2017) “Actividad antitumoral de un extracto de romero (Rosmarinus officinalis L.) en modelos in vitro e in vivo de cáncer de colon.” Tesis en acceso abierto en RediUMH (Universidad Miguel Hernández, España) - http://dspace.umh.es/handle/11000/3619
Extracto: <<El objetivo del presente trabajo ha sido determinar la actividad antitumoral de un extracto de romero (ER) enriquecido en terpenoides en modelos in vitro e in vivo de cáncer colorrectal humano (...) La capacidad antiproliferativa del extracto ha sido corroborada en un modelo animal de xenotransplantes humanos de cáncer de colon y se ha verificado en ratas su ausencia de toxicidad a los niveles máximos permitidos por la regulación existente relativa a ensayos animales.>>
[Translation: <<The objective of this work has been to determine the antitumor activity of a terpenoid-enriched rosemary extract (ER) in in vitro and in vivo models of human colorectal cancer (...) The antiproliferative capacity of the extract has been corroborated in an animal model of colon cancer human xenotransplantation and its absence of toxicity has been verified in rats at the maximum levels allowed by the existing regulation related to animal tests.>>]

Pérez-Sánchez A, Barrajón-Catalán E, Ruiz-Torres V, Agulló-Chazarra L, Herranz-López M, Valdés A, Cifuentes A, Micol V. (2019). "Rosemary (Rosmarinus officinalis) extract causes ROS-induced necrotic cell death and inhibits tumor growth in vivo." Nature / Sci Rep. doi: 10.1038/s41598-018-37173-7. PMID: 30692565 - https://www.ncbi.nlm.nih.gov/pubmed/30692565

Cattaneo L, Cicconi R, Mignogna G, Giorgi A, Mattei M, Graziani G, Ferracane R, Grosso A, Aducci P, Schininà ME, Marra M. (2015) "Anti-Proliferative Effect of Rosmarinus officinalis L. Extract on Human Melanoma A375 Cells." Public Library of Science. doi: 10.1371/journal.pone.0132439. - https://www.ncbi.nlm.nih.gov/pubmed/26176704

Shuai Han, Xin Li, Yun Xia, Zhengsen Yu, Ningning Cai, Satish R. Malwal, Xu Han, Eric Oldfield, Yonghui Zhang. (2019) "Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells." J. Med. Chem. American Chemical Society. PMID: 31725297. DOI: 10.1021/acs.jmedchem.9b01405 - https://www.ncbi.nlm.nih.gov/pubmed/31725297
Extract: <<Here, we report the discovery and development of HsFPPS inhibitors based on the phenolic diterpene carnosic acid (CA), an antimicrobial found in rosemary and sage, which showed better cellular anticancer activities than the bisphosphonate drug zoledronate in pancreatic cancer cell lines, as well as an HsFPPS-dependent mechanism of action.>>

---------------------------------------------------------

- Oregano
Active Principle: Carvacrol, Thymol
(Extra: also anti-inflammatory, analgesic, antioxidant, antiseptic / antimicrobial / antibacterial, effective topically for infections)

Sources:

Benhalilou Nehla, et al. (2019) "Origanum majorana Ethanolic Extract Promotes Colorectal Cancer Cell Death by Triggering Abortive Autophagy and Activation of the Extrinsic Apoptotic Pathway." Frontiers in Oncology. PMID: 31497536. PMCID: PMC6712482. doi: 10.3389/fonc.2019.00795. - https://www.ncbi.nlm.nih.gov/pubmed/31497536

Peter Kubatka, et al. (2017) "Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model." European Journal of Nutrition. PMID: 26907089. doi: 10.1007/s00394-016-1181-5. - https://www.ncbi.nlm.nih.gov/pubmed/26907089

Balusamy SR, Perumalsamy H, Huq MA, Balasubramanian B. (2018) "Anti-proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines." Biomedicine & Pharmacotherapy, Elsevier Masson. - PMID: 30372889. doi: 10.1016/j.biopha.2018.10.028. https://www.ncbi.nlm.nih.gov/pubmed/30372889

Li Wang et al. (2018) "Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2." Oncotarget. PMID: 30344937. PMCID: PMC6188138. doi: 10.18632/oncotarget.24409 - https://www.ncbi.nlm.nih.gov/pubmed/30344937

Whasun Lim, Jiyeon Ham, Fuller W. Bazer, Gwonhwa Song (2018) "Carvacrol induces mitochondria-mediated apoptosis via disruption of calcium homeostasis in human choriocarcinoma cells." Journal of Cellular Physiology. PMID: 30070691. doi: 10.1002/jcp.27054. - https://www.ncbi.nlm.nih.gov/pubmed/30070691

Jorge J. De La Chapa, Prajjal Kanti Singha, Debbie R. Lee, Cara B. Gonzales (2018) "Thymol inhibits oral squamous cell carcinoma growth via mitochondria-mediated apoptosis." Journal of Oral Pathology and Medicine. PMCID: PMC6105452. DOI: 10.1111/jop.12735 - https://www.ncbi.nlm.nih.gov/pubmed/29777637

---------------------------------------------------------

Following is an additional list of consumables with known and proven anti-tumoral effects.

Parsley
Active Principle: apigenina

Plum / Peach
Active Principle: anthocyanins (cyanidin-3-glucoside), carotenoids, phenolics (chlorogenic acid and glycosides) (*note: another that kills cancerous cells without damaging healthy cells)
Warning: some sources say not safe for cats

Watercress
Active Principle: isotiocianato de feniletilo (PEITC) [MEITC also recommended]

Seaweed [Mozuku (Cladosiphon okamuranus), Mekabu (part of Wakame) and Kombu (Laminaria japonica) and Hondawara]
Active Principle: fucoidan (* contraindications: high iodine and salt content)

Garlic
Active Principle: diallyl disulfide (+ lysine and quercetin)
Warning: not safe for cats.

Green Tea
Active Principle: EGCG

Blueberries and other berries
Active Principle: flavonoids and anthocyanins [antioxidant polyphenolic; grapes / peanuts: resveratrol; blackberry / raspberry: anthocyanins]
Warning: some berries not safe for cats.

Tomatoes
Active Principle: licopeno, oligosacarias (https://www.sciencedirect.com/science/article/pii/S0144861716314138)

Grenade
Active Principle: polyphenols (flavonoids and tannins), ellagic acid and punicalagin(https://www.hindawi.com/journals/ecam/2015/258598/ + chart https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560105/)
Warning: not safe for cats

Apple
Active Principle: fitoquímicos

Walnuts
Active Principle: fitosteroles

Yogurt
Active Principle: "bacterias buenas" del yogurt

Coffee (topic use)
Active Principle: caffeine (inhibits damaged ATR proteins)

Flax seeds
Active Principle: alpha-linolenic acid (omega-3); lignans (phytoestrogens and antioxidants) and dietary fiber

Carrot, Sweet Potatoes
Active Principle: beta-carotene and tocopherol

Pumpkin
Active Principle: carotenoids (alpha-carotene, beta-carotene, lycopene, lutein, cryptoxanthin)

Spinach / chard / lettuce
Active Principle: 13 different flavonoid compounds

Onion
Active Principle: onionin A
Warning: not safe for cats

Brewer's yeast
Active Principle: synthetic RNA oligonucleotides

Soy / Tofu
Active Principle: Genistein

Milk*
Active Principle: TRAIL, vitamin C and “Hamlet”. (* Warning: also contain casein = carcinogenic)
Warning: most cats are intolerable

Omega 3 foods*
Active Principle: resolvin, docosahexaenoic acid, eicosapentaenoic acid (against sarcopenia / cachexia), n-3 PUFAs (anti-inflammatories. * Note: some studies says may cause cancer)
https://www.ncbi.nlm.nih.gov/pubmed/30009833
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728677/
https://www.ncbi.nlm.nih.gov/pubmed/17640164
https://www.bmj.com/content/bmj/4/5883/1.1.full.pdf

Mushrooms* (e.g.shiitake, maitake, reishi, etc)
https://www.cancer.gov/espanol/cancer/tratamiento/mca/paciente/hongos-pdq
https://www.gacetamedica.com/especi...ra-nuevos-farmacos-contra-el-cancer-FF1689007

(*) Foods that merely <prevent> cancer were not included in this list. Only foods to <treat> post-diagnosis cancer (which may or may not also be preventive) were included.

ALSO OF NOTE:
* promoters of NK cells (Natural Killers, attack tumors) : carotenoids, vitamin E
* promoters of helper Tcells : CD4 + CD25 + Foxp3 + Tregs in PP, carotenoids

ALSO OF NOTE:
Opposing research : articles that speaks against antioxidants in cancer patients:
https://www.scientificamerican.com/...xidantes-mas-bien-podrian-empeorar-el-cancer/
https://www.cancer.gov/espanol/noticias/temas-y-relatos-blog/2015/antioxidantes-metastasis

---------------------------------------------------------

ABOUT USING THE LIST AS DIET (keywords: herbal medicine, fitotheraphy, diet therapy)
Cancer diet note: relatively low in simple sugars, moderate amounts of highly bioavailable or high biological value proteins (white meat, fish, milk, cheese, yogurt), increased fiber (spinach, broccoli) and moderate amounts of polyunsaturated fatty acids n- 3 (fish, shellfish) but avoid PUFA amino acids.

Anecdotical experience of cat owner keeping the cancer in her cat at bay using diet -links:
https://smoda.elpais.com/belleza/mi-cura-del-cancer-fue-un-milagro-muy-currado/ (fitothery experience [spanish])

--------------------------------------------------------

NON-FOOD/CONDIMENT TREATMENTS OF NOTE

* Salinomycin / salinomicina (antibiotic for poultry, discovered to be highly effective)
https://www.nature.com/articles/nchem.2778

About Salinomycin (trade name: Cassab Feed Microline, Bovisacc)
Description: antibiotic for poultry.
Active Principle: ionophore (coccidiostacts)
Contraindication: can cause hypocalcemia and leukocytes

Sources:

Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, Zhang J, Pan J. (2019) "Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma." Molecular Cancer. PMID: 31718679. PMCID: PMC6852970. DOI: 10.1186/s12943-019-1068-1 - https://www.ncbi.nlm.nih.gov/pubmed/31718679

Czerwonka D, Urbaniak A, Sobczak S, Piña-Oviedo S, Chambers TC, Antoszczak M, Huczynski A. (2019) "Synthesis and Anticancer Activity of Tertiary Amides of Salinomycin and Their C20-oxo Analogues." ChemMedChem. PMID: 31702860. doi: 10.1002/cmdc.201900593. - https://www.ncbi.nlm.nih.gov/pubmed/31702860

Novohradsky V, Markova L, Kostrhunova H, Trávnícek Z, Brabec V, Kasparkova J. (2019) "An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis." Nature. doi: 10.1038/s41598-019-49774-x. - https://www.ncbi.nlm.nih.gov/pubmed/31527683

Zhongyuan Wang, et al. (2019) "Salinomycin exerts anti-colorectal cancer activity by targeting the ß-catenin/T-cell factor complex." British Journal of Pharmacology. PMID: 31236922. PMCID: PMC6692576. doi: 10.1111/bph.14770. - https://www.ncbi.nlm.nih.gov/pubmed/31236922

Hero T, Bühler H, Kouam PN, Priesch-Grzeszowiak B, Lateit T, Adamietz IA. (2019) "The Triple-negative Breast Cancer Cell Line MDA-MB 231 Is Specifically Inhibited by the Ionophore Salinomycin." Anticancer Research. PMID: 31177119. doi: 10.21873/anticanres. - https://www.ncbi.nlm.nih.gov/pubmed/31177119

Otro: https://www.elmundo.es/elmundosalud/2009/08/14/oncologia/1250228714.html

More: https://www.ncbi.nlm.nih.gov/pubmed/?term=salinomycin+tumor
https://www.nature.com/articles/nchem.2778

-----------------------------------

* Legasil (food supplement for liver problems based on sea thistle. Active Principle: silibinin)

(*) About Legasil (marine thistle molecule. Active Principle: silibinin)
[English Translation: << the case of a 39-year-old patient with breast cancer and bone and liver metastases, who came to her office in 2014. The woman did not respond to chemotherapy - with paclitaxel from Pacific yew - and the doctors gave her barely a month of life. Given his liver problems, Bosch prescribed Legasil, a milk thistle-based food supplement marketed as a liver protector. Unexpectedly, the patient reacted and survived 20 months.
(...) The pharmaceutical companies consulted have refused to participate, "perhaps for fear of not recovering the investment," according to Bosch. The treatment with Legasil that they have used this time costs about 100 euros a month, compared to the usual thousands of euros in cancer drugs]

[Original: <<el caso de una paciente de 39 años con cáncer de mama y metástasis en hueso e hígado, que llegó a su consulta en 2014. La mujer no respondía a la quimioterapia —con el paclitaxel del tejo del Pacífico— y los médicos le daban apenas un mes de vida. Dados sus problemas en el hígado, Bosch le indicó Legasil, un complemento alimenticio a base de cardo mariano, comercializado como protector hepático. Inesperadamente, la paciente reaccionó y sobrevivió 20 meses.
(...) Las farmacéuticas a las que han llamado a la puerta han rechazado participar, “quizá por temor a no recuperar la inversión”, según Bosch. El tratamiento con Legasil que han empleado esta vez cuesta unos 100 euros al mes, frente a los miles de euros habituales en los fármacos oncológicos>>]

https://elpais.com/elpais/2018/06/11/ciencia/1528727883_239077.html

Sources:

Bosch-Barrera J, et al.
- "Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin." (2016) Oncotarget. doi: 10.18632/oncotarget.7900. PMID: 26959886
https://www.ncbi.nlm.nih.gov/pubmed/26959886
- "Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy." (2015) Cancer Treatment Reviews. doi: 10.1016/j.ctrv.2015.04.008. PMID: 25944486
https://www.ncbi.nlm.nih.gov/pubmed/25944486
- "Targeting STAT3 with silibinin to improve cancer therapeutics." (2017) Cancer Treatment Reviews. doi: 10.1016/j.ctrv.2017.06.003. PMID: 28686955
https://www.ncbi.nlm.nih.gov/pubmed/28686955
- "Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient." (2014) Anticancer Research: Internacional Journal of Cancer Research and Treatment (by The International Institute of Anticancer Research). PMID: 25075066
http://ar.iiarjournals.org/content/34/8/4323.long

---------------------------------------------------------

Own notes (Rey, Nadia I.):

My experience was with a metastatic oral melanoma in a cat. The elements used were the first six (Olive Oil, Oregano, Rosemary, Turmeric, Broccoli and Rose Bengal), topically or intralesionally, with occasional use of other elements such as spinach and watercress (used to counteract the anticoagulant effect of the other elements). [Items like plum and garlic ruled out for toxicity in cats.]

The effects were seen within a few hours. In 24 hours, it left a hole in the affected gum that reached the jaw bone, without damaging healthy tissue and without causing pain. The continued use of these elements in a topical / intralesional way reduced the paralysis in the tongue and allowed her to eat, at the same time that their antibiotic properties kept the area disinfected (a cleaning and reapplication process was carried out after each meal).

At the same time, the taking of three syrups that functioned as adjuvants of a veterinary immunotherapeutic treatment developed with molecules of turmeric, blueberry and other elements mentioned, developped by the Veterinary Immunotherapeutic Center (CIV) in Buenos Aires, improved her mood immensely - and therefore her quality of life. .

The discovery of the antitumoral effect of these elements was accidental: it was applied topically because the analgesic effect of these natural elements was sought to avoid the use of corticosteroids, because the kidney was affected as a result of three surgeries. Following this, this list was researched online and compiled. It may be incomplete.

------------------------------------------------------------

* Reference data for topical / intralesional application in cancer diagnosis (melanoma):

Formula (dose) in humans:
Olive oil 50ml per day (recommended consumption limit).
Broccoli 30 to 60gr per day (recommended consumption limit).
Turmeric and oregano 6gr (recommended limit in plant intake) or 10 drops per day in essential oil.
Rosemary 10gr (recommended limit in plant intake) or 10 drops per day in essential oil.
Rose Bengal 0.1ml to 15ml, 1 to 4 times total treatment.

Formula in cats:
Aceite oliva 1,5ml
Brócoli 1gr
Curcuma y oregano 0,2gr
Romero 1/2 gota
Rose Bengala 1,4ml

(*) Amounts may vary according to the weight of the patient. These are the minimal references.

Contact information:
@ Nadia Irene Rey (2019)
[email protected]
54 9 341 (15)3265069

Wow!!! Thank you so much for such a wealth of information! Definitely going to use the info you gave me to do some research! The tumor started on her chin 2 years ago! It’s completely solid through and through. I’m all about trying things that are natural!

Sherrybaby77 · Apr 3, 2022

NadiaRey said:
I wanted to share one last thing. These are photos of the how the tumor in my cat looked when it was fully grown (She had three surgeries, and each time the tumor grew again, or bigger. Also the white things: it got infected because of the first surgery.)

View attachment 414381 View attachment 414382

... and after I used the intralesional method.

View attachment 414383 View attachment 414384

The teeth were already yellow from decay because this was three months in.

They told me Sueño shouldn't have lasted a month. She lasted five. And it was only because the third sugery opened bloodvesels to the back of the throat, making the cancer spread and her unable to drink water, that we decided to her go. Otherwise, she was looking unbelievable strong. Specially considering she was 18 years old. She was even putting on weight. She was a fighter.

*

Sorry I just went on a rant about my experience or oversharing. I thought maybe you would need more context.

I'm not gonna lie, I was fearfully enamoured with the idea of the Intralesional Treatment reaching even the place where the cancer had spread. It kind of blows my mind this info isn't shared widely. Bengal Rose tincture seems to be the only known thing that treats metastatic (4-stage) cancer, without the toxicity of chemotheraphy.

I also want to make clear I'm not a doctor or vet or medical researcher, I just read research others did. As per shown up there.

And keep in mind I didn't get the ok from the vets. (How could they okay it? It hasn't even been cleared for humans, to okay it would be to malpractice.)

But that is not to say it's in itself unsafe. What would be unsafe is to not respect the dosis, which I drafted using as reference what has been done with humans and what was used safely in rats before them, as per my cat's weight.

It's kind of promising a miracle. I know that's irresponsible. But, though I only have Sueño experience as reference, I can tell at least I didn't hurt her with this.

And it's not possible for me to promise it will work for you for sure, but of course I'll at least give you the data.

Best of luck.

My cat Chloe’s teeth look just like Sueño teeth. One of her teeth actually chipped. Unfortunately, I’ve learned that if it doesn’t make pharmaceutical companies and doctors money the natural remedies which are sometimes cheaper and don’t need a doctors prescription, are not even looked at! It’s really all about money and not health!
I’m so sorry that you lost Sueño. I appreciate you helping my fur baby with the experience you went through with your fur baby! Thank you again!!!

NadiaRey · Apr 7, 2022

I'll just be glad if it helps anybody else. Hope it does for you.

As for the pharmaceuticals, pardon my bit of a rant. I did a little digging and there's actually a much sillier, dummer explanation to why useful treatments like these are not the "normal". ...Well, not that you need this extra bit but, if you or anybody else is bored, here it is:

First let's think about the system: A doctor, when prescribing a new treatment (drugs mostly), they don't do it because a new research came out in a magazine - they do it because they are presented that option via the pharmaceutical envoys that send free samples. That is, the doctors offer you, the patient, those samples they themselves were offered. And then, with enough people giving the doctor "reviews" about what did or did not work, the more positive reviewed treatment becomes most used aka the standard.

Meanwhile, the pharmaceuticals have no reasons to introduce the knowledge of effective cheaper treatment (say, turmeric tincture as a viable option for the also-obscure intralesional treatment) because... it's literally not their job. They earn money if you use their thing, for one. They themselves may have invested in the more expensive treatment so they will only lose money if the cheaper thing becomes the standard. Allegedly.

But all of this means we are stuck being dependent on pharmaceuticals for the introducing of *any* new treatment, but *those* people are looking out for themselves.

By the way, doctors do things like this because, if the drugs do something wrong, then the responsibility is not theirs but the lab, right? Plus, the lab (aka pharmaceuticals) has so many lawyers and legal protection that, even if something was their fault, they could mostly come out unscathed anyways. The doctors feel protected offering these drugs because of this situation.

By the way, I'm not shaming the doctors: lawsuits are very scary. But the medics possibly have become too comfortable in this idea of legal security given by pharmaceutical - which by the way is completely misguided: a lawsuit could fall both the doctor and the pharmaceutics (and the later are *not* going to share their lawyers...)

I'm also not shaming the professionals for not knowing about the treatments. There are hundred of new investigations every day and little time while you are seeing thousands of patients to keep up. Though it's always a relief when you find the kind of doctor that does their investigations... And also, bless the internet for allowing us to know what's being investigated in India or Chile, but damn the internet for burrying it under a sea of trash content continuously being poured into the thing.

But yeah, it's a problem. When asked, the doctors I spoke to all said the same thing regarding being scared of what could be considered malpractice... even if, at the same time, they do introduce treatments, if they come from a lab. And they do it all the time, and they don't seem to notice the contradiction. Life is weird like that.

So it's not Big Pharma burrying the knowledge per say. It's that, since the companies have highjacked the process to have treatment-introduction depend on them, and have no incentive to introduce any alternative ways, and meanwhile the doctors have become complacent and scared of their own responsibility to do any differently, we are stuck on a loop.

But I was very angry when I found all these *fully* investigated things and little to no doctor who knew or vouched for those as possible treatments. But if I had known what I know now, I would have tried much earlier and spared my cat a lot of hurt. There's no hell that explains how unfair this whole situation is. The patients are the ones suffering from it, finantially and with their lives...

Sorry I just went on a rant. I just found this information useful, because it provided some clarity for me, to make sense of an unfair situation. I find that being uncertain can sometimes be worse than receiving a bad news... Maybe because being angry beats being scared... Anyways. In case it provides that clarity for you too. Best of luck, and keep us posted.

Sherrybaby77 · Apr 9, 2022

NadiaRey said:
I'll just be glad if it helps anybody else. Hope it does for you.

As for the pharmaceuticals, pardon my bit of a rant. I did a little digging and there's actually a much sillier, dummer explanation to why useful treatments like these are not the "normal". ...Well, not that you need this extra bit but, if you or anybody else is bored, here it is:

First let's think about the system: A doctor, when prescribing a new treatment (drugs mostly), they don't do it because a new research came out in a magazine - they do it because they are presented that option via the pharmaceutical envoys that send free samples. That is, the doctors offer you, the patient, those samples they themselves were offered. And then, with enough people giving the doctor "reviews" about what did or did not work, the more positive reviewed treatment becomes most used aka the standard.

Meanwhile, the pharmaceuticals have no reasons to introduce the knowledge of effective cheaper treatment (say, turmeric tincture as a viable option for the also-obscure intralesional treatment) because... it's literally not their job. They earn money if you use their thing, for one. They themselves may have invested in the more expensive treatment so they will only lose money if the cheaper thing becomes the standard. Allegedly.

But all of this means we are stuck being dependent on pharmaceuticals for the introducing of *any* new treatment, but *those* people are looking out for themselves.

By the way, doctors do things like this because, if the drugs do something wrong, then the responsibility is not theirs but the lab, right? Plus, the lab (aka pharmaceuticals) has so many lawyers and legal protection that, even if something was their fault, they could mostly come out unscathed anyways. The doctors feel protected offering these drugs because of this situation.

By the way, I'm not shaming the doctors: lawsuits are very scary. But the medics possibly have become too comfortable in this idea of legal security given by pharmaceutical - which by the way is completely misguided: a lawsuit could fall both the doctor and the pharmaceutics (and the later are *not* going to share their lawyers...)

I'm also not shaming the professionals for not knowing about the treatments. There are hundred of new investigations every day and little time while you are seeing thousands of patients to keep up. Though it's always a relief when you find the kind of doctor that does their investigations... And also, bless the internet for allowing us to know what's being investigated in India or Chile, but damn the internet for burrying it under a sea of trash content continuously being poured into the thing.

But yeah, it's a problem. When asked, the doctors I spoke to all said the same thing regarding being scared of what could be considered malpractice... even if, at the same time, they do introduce treatments, if they come from a lab. And they do it all the time, and they don't seem to notice the contradiction. Life is weird like that.

So it's not Big Pharma burrying the knowledge per say. It's that, since the companies have highjacked the process to have treatment-introduction depend on them, and have no incentive to introduce any alternative ways, and meanwhile the doctors have become complacent and scared of their own responsibility to do any differently, we are stuck on a loop.

But I was very angry when I found all these *fully* investigated things and little to no doctor who knew or vouched for those as possible treatments. But if I had known what I know now, I would have tried much earlier and spared my cat a lot of hurt. There's no hell that explains how unfair this whole situation is. The patients are the ones suffering from it, finantially and with their lives...

Sorry I just went on a rant. I just found this information useful, because it provided some clarity for me, to make sense of an unfair situation. I find that being uncertain can sometimes be worse than receiving a bad news... Maybe because being angry beats being scared... Anyways. In case it provides that clarity for you too. Best of luck, and keep us posted.

I completely understand how you feel! Looking up Rose Bengal and how it shrinks cancer cells blew my mind. May I ask where did you order Rose Bengal? I just ordered it from Amazon…but it says strictly for science experiments. But here’s the deal as my cats cancer that started on her chin is now gotten so big it’s inside of her mouth and has taken up most of her chin area…she will likely have more issues eating and possibly suffer which I won’t allow. So I have the choice when it comes to it to put her down, or try to shrink this cancer myself. I am desperate to help her as if she were my human child!
I know in the end this cancer will grow to the point where she won’t be comfortable…so I have nothing to loose at this point by trying the Rose Bengal!

Sherrybaby77 · Apr 9, 2022

NadiaRey said:
I'll just be glad if it helps anybody else. Hope it does for you.

As for the pharmaceuticals, pardon my bit of a rant. I did a little digging and there's actually a much sillier, dummer explanation to why useful treatments like these are not the "normal". ...Well, not that you need this extra bit but, if you or anybody else is bored, here it is:

First let's think about the system: A doctor, when prescribing a new treatment (drugs mostly), they don't do it because a new research came out in a magazine - they do it because they are presented that option via the pharmaceutical envoys that send free samples. That is, the doctors offer you, the patient, those samples they themselves were offered. And then, with enough people giving the doctor "reviews" about what did or did not work, the more positive reviewed treatment becomes most used aka the standard.

Meanwhile, the pharmaceuticals have no reasons to introduce the knowledge of effective cheaper treatment (say, turmeric tincture as a viable option for the also-obscure intralesional treatment) because... it's literally not their job. They earn money if you use their thing, for one. They themselves may have invested in the more expensive treatment so they will only lose money if the cheaper thing becomes the standard. Allegedly.

But all of this means we are stuck being dependent on pharmaceuticals for the introducing of *any* new treatment, but *those* people are looking out for themselves.

By the way, doctors do things like this because, if the drugs do something wrong, then the responsibility is not theirs but the lab, right? Plus, the lab (aka pharmaceuticals) has so many lawyers and legal protection that, even if something was their fault, they could mostly come out unscathed anyways. The doctors feel protected offering these drugs because of this situation.

By the way, I'm not shaming the doctors: lawsuits are very scary. But the medics possibly have become too comfortable in this idea of legal security given by pharmaceutical - which by the way is completely misguided: a lawsuit could fall both the doctor and the pharmaceutics (and the later are *not* going to share their lawyers...)

I'm also not shaming the professionals for not knowing about the treatments. There are hundred of new investigations every day and little time while you are seeing thousands of patients to keep up. Though it's always a relief when you find the kind of doctor that does their investigations... And also, bless the internet for allowing us to know what's being investigated in India or Chile, but damn the internet for burrying it under a sea of trash content continuously being poured into the thing.

But yeah, it's a problem. When asked, the doctors I spoke to all said the same thing regarding being scared of what could be considered malpractice... even if, at the same time, they do introduce treatments, if they come from a lab. And they do it all the time, and they don't seem to notice the contradiction. Life is weird like that.

So it's not Big Pharma burrying the knowledge per say. It's that, since the companies have highjacked the process to have treatment-introduction depend on them, and have no incentive to introduce any alternative ways, and meanwhile the doctors have become complacent and scared of their own responsibility to do any differently, we are stuck on a loop.

But I was very angry when I found all these *fully* investigated things and little to no doctor who knew or vouched for those as possible treatments. But if I had known what I know now, I would have tried much earlier and spared my cat a lot of hurt. There's no hell that explains how unfair this whole situation is. The patients are the ones suffering from it, finantially and with their lives...

Sorry I just went on a rant. I just found this information useful, because it provided some clarity for me, to make sense of an unfair situation. I find that being uncertain can sometimes be worse than receiving a bad news... Maybe because being angry beats being scared... Anyways. In case it provides that clarity for you too. Best of luck, and keep us posted.

Here is what her growth looks like today, April 9, 2022:

Sherrybaby77 · Apr 9, 2022

Sherrybaby77 said:
Here is what her growth looks like today, April 9, 2022:

I am hoping the Rose Bengal will help! It’s gotten much bigger in just the last couple of weeks!

NadiaRey · Apr 16, 2022

I'm so sorry it took me so long to get back to you. How are things now? Did you manage to try Rose Bengal? Remember, if you don't find that, Turmeric tincture (or even powder) and olive oil extra virgin are both good for reducing the tumor immediately. (Remember turmeric also cleans wounds from bacteria and microbes.)

Yeah, I know about the rapid growth... It's maddening, but just a week and any tumor with access to oxygen gets so big so fast. Again, very sorry I didn't check in here earlier. I'm an idiot. I hope anything I mentioned before was of any use. It almost gave me an ulcer doing it myself so I know it's a terrible thing to ask, but I stand with what I said about draining the tumor, and injecting what's left. (Later use meat in diet to prevent anemia.)

When mine had problems eating, I put the chicken bits almost pushing them in when she opened her mouth. Again, I know how stressful this is, but hang in there. You got this.

Also, the change in food. Don't let the tumor get access to any nutrients it can use. (No package catfood, only homemade. If meat, no fat, preferrably chicken or turkey, and soaked in anti-tumoral condiments like oregano or olive oil. Nothing with sugar. So on so forth.)

Again, so sorry I'm this late...

Cat cancer growth

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