I've owned three calicos, fostered a dilute calico, and my neighbor owns a dilute calico that liked to come into our yard. All had "interesting" dispositions except the one that we fostered. However, she was only a few months old, so she may have grown into her calico heritage. She was also the only longhair in the bunch. The rest had your typical calico temperment.
My experience was that calicos tend to be independent and dominant. They don't take anything from cats, dogs, or humans. They also like to wander and patrol their territory. The have a kind of a "I'm bad and I'm beautiful" attitude. They do seem to get calmer in old age. Like, past 10 years and they are willing to let you pick them up.
If you are "their" owner though, you can usually come to an understanding while they're young.
If you want a pushover cat, get an orange tabby. They seem to be complete love cats. I've actually not met a mean orange tabby.