I asked my vet about this. She said some cats have an allergic reaction to Febreze(Twitch is one of them). She said not to use aerosols, or air sprays. If you need to use them, keep the cat out of the room/area for a half hour. Provided they don't inhale it, they are usually OK. I use the Oust fragrance free. I have mom spray it before the cats are allowed upstaris(before she showers). I spray it in my bedroom & the hallway by the litter pans after the cats get up. That helps to cut down on odors.
If I remember right, they make something that will spray an air sanitizer(or something) into the air. It attaches right to the litter box. You can find it at Petsmart.com or Petco.com. I have no idea what it is called, though.