Here is my mom's family: We are in and are firmly planted in Chicago (my dad is a native, and come hell or high water, he's absolutely not leaving this city). My aunt Deb (my mom's oldest sister) and Uncle Ted are in Tampa. My Aunt Lynn and Uncle John (and my great-aunt Betty) are in Olathe, Kansas. My Aunt Wendy and Uncle Bill are on a ranch near Havre, Montana. Most of my mom's other relatives (who are called my "aunts", "uncles" and "cousins" regarless of how I'm actually related to them) are scattered in the plains states in the heart of the midwest, like Wisconsin, Nebraska, South Dakota, Oklahoma. They come from a family of Scandinavians who came over in the late 19th century and became farmers. Many of my relatives still are, as you can probably discern from their locations.
Our solution? We rely heavily on the internet and calling plans. we send a lot of snail mail, which is heartwarming, yet necessary. Every couple of years, we throw a GIGANTIC family reunion that requires us to spend 10-15 days camping in the middle of one of those plains states. Often (as in once a year or more), my mom and her mom and sisters all gather with the sister in Tampa for some R&R. It's why I've been to Disney World a good 30 times in my 20 years.
My dad's family, on the other hand, is extremely Italian (like, came over when my daddy was little and still speak the language, etc) and extremely urbane. My Big Fat Italiam family (I easily have 20 cousins on that side of the family ALONE) is concentrated in just 4 locales: Chicago, Boston, New York and Reggio, Calabria in the south of Italy.