I believe you may be referring to Hannibal, but Clarice says "Not in a thousand years" not "Not in a million years"....if I remember right. I remember Lector saying "Oooooohh....not in a thousand years....that's my girl" after she said that.
thanks, Sofiecusion....it was 2am and I just wasn't willing to get out the tape and cue it to that spot, so I tried to get the jist before I went to bed.