Cat with chronic cystitis

I have a 9 year old female cat that for the past year a a half (started in aug 2015) has had chronic bloody urine. Brought her to the vet initially because she was vomiting and not eating but that was fixed and then this started and hasn't improved no matter what we've tried. I was checking her urine almost every 2 weeks and trying every kind of antibiotic/Chinese herbal remedy that could help her and only ever got slight improvements. The doctor started her on steroids (prednisolone) and we stopped the antibiotics because they weren't working, and we kept her on the pred and checked her glucose levels frequently and she was good on that so we gave her 3-4 months to see how she was doing then would check her again. So I checked her in September and now she has bacteria (cocci) in her urine. We put her on amoxicillin and for the first time in a year, we got yellow urine but she still had bacteria so we sent out a culture but it came back negative. So we left her on the amoxi for another 2 weeks till we could run another urine and she still had bacteria and the doctor was frustrated because she could see the bacteria on the slide when it was stained and it didn't make sense as to why nothing was growing, so we sent out another one which came back negative. We stopped the amoxi and just kept her on the pred for a month and then re checked her urine, and the same thing happened again- so we sent out another culture and still came back negative. I'm wondering- what can cause this type of bacteria in her urine and why are the cultures always negative? The dr isn't really sure, and shes just as frustrated as I am. She's has presumed interstitial cystitis and the bacteria thing is new so it's just stressful. She's a very anxious cat and gets stressed by my other cat, but i have 6 litter boxes for 2 cats and numerous food/water dishes, i've tried every kind of feliway/spirit essence/ laser therapy/ reiki/ rescue remedy- basically anything to reduce her stress and nothing helps I just want her to be healthy. 

What food is she eating? NO kibble for cats with urinary issues. None. Wet or raw food with added water and water fountains to encourage drinking. Filtered water only. Have you tried d-mannose or slippery elm? Both food for urinary health. 

http://www.littlebigcat.com/health/urinary-tract-disorders-in-cats/

She has been eating royal canin urinary so ever since this started. She won't eat wet food, never has and i do know it'll help her but she just doesn't like wet food. I have numerous water bowls around the house and one of those water fall ones for her because she likes running water

Have you tried any calming remedies with your cat? Her issue may be stress induced (cats can get stressed by literally anything). You could start with Feliway diffusers or a calming collar.

Also, what canned foods have you tried?

Have you tried using toppers (freeze-dried meat treats or freeze-dried raw food or crushed up dry food) on canned food to try to entice her?

Here is an article on transitioning a kitty to wet food  http://www.thecatsite.com/a/transit...-to-a-new-type-of-food-canned-raw-or-homemade  it can be a long slow process and some kitties can't be fully  transitioned.  Even replacing some of the kibble with wet food will help.

Some kitties have gotten relieve from glucosmine chondroitin has helped some kitties.  It helps  to heal and rebuild the lining of the bladder.  My vet recommends the powder that is mixed in with food rather than treats.  The treats have other things in  them and they may not deliver a dose that will help.  Cosequin is the one that is best know  
I don't understand the thing with the bacteria either.  It doesn't make sense to me.

It's really vital you get her on wet food. At least part of the issue is that she's on a kibble only diet. RX foods are hit and miss, and mostly a waste of money because they contain a lot of fillers, often times cats wont even eat them. Cats naturally have a low thirst drive, as they are designed to get water from their prey, or food. So feeding a kibble old diet is extremely dehydrating, and because their thirst drive is low they don't typically drink enough water to make up for that dehydration. Most of the time cats with urinary issues or a history of blockages are on a kibble only diet. Water fountains encourage drinking because of the moving water, and they also help keep the water clean, so investing in one is a good idea. There are hundreds of wet foods on the market. The key to transitioning a cat to wet food is time, patients, and finding a food they like. Some cats like pate, some like shreds, some like gravy, some like chicken only, etc. Weruva, Tikicat, Soulistic, Merrick LID, are some good ones, you could also try a freeze dried food like Stella and chewy or Primal, because they require that you add water you can control how wet the food is and that helps with cats that aren't used to eating wet food. Use toppers to entice her to eat like bonito flakes, which are irresistible to most cats. 

Here's a good article about transitioning stubborn kibble addicts to wet food. I transitioned a 12 year old kibble only fed cat to raw food, and a stubborn Bengal, so anything is possible. 

http://catinfo.org/docs/TipsForTransitioning1-14-11.pdf