Effects after domitor and antisedan.

Hey everyone, I'm a worried cat momma right now. Any insight or advice is greatly appreciate. Here's the scoop:

My 10.5 year old, 8 lb cat, Luna was at the vet today for an x ray, as she hasn't pooped since last friday. (She was at the vet last Friday on IV for dehydration and blood work. Results: High liver enzymes and low RBC #s. Given sulcrate. Zeniquin and metronidazole.)
She was taken in around 12:30 today to have the x ray and enema done. I picked her up at 2:30 and she's very "drunk" . The vet said the enema pulled out soft stool, and now she is clear. The x ray showed some infection in her intestines and to keep on with the antibiotics. It is now 5:00. Her pupils are dilated as wide as her eyes allow (but do restrict in light). She is disoriented and unstable, mostly in her back legs. She is lethargic yet restless. She was given Domitor and antisedan

I'm sorry no one responded to your questions.  How is Luna now?  Back to normal? 

Yes, How is Luna???

I would think that she is still recovering from the effects of the sedation.. My Vet does not release an animal until it eats, pees...

I am not familiar with the drugs she was given, but I honestly feel you should contact your Vet with your concerns.. 

Was she given an instruction sheet after the clean out??

I really would call the Vet.. 

If she does not improve in a few more hours, I would definitely either take her back to your Vet, or to an emergency Vet... I know it is expensive, but you love your baby and do not want to take any chances with her having a reaction to any drugs.. she should be hydrated and eating soon...

I think she is just exhausted from the entire episode: think fear, pain, plus sedation...but you really want to make sure she is ok...

Did the Vet give you any instructions???   or what to expect?

Or even giving her anything for the constipation??

These are things you need to find out from your Vet..

Please follow up on these things... in  the meantime (((Hugs)) to you...

Hi, thank you for the concerns!!!
So to update. She finally came down from the sedative, yesterday around noon . She has a great appetite, no issues eating. I add water to her food to increase hydration as well. She loves it.
She has urinated multiple times in her litter box.
The vet has called to check on her status and because she still hasn't pooped since the enema, he said increase the lactulose to 3ml a day instead of 2. I feel like I am noticing in the mornings that her anaemia seems to be reversing but she looks pale again a couple hours after the lactulose. Her afternoon meals don't include lactulose and she gets pink again. After dinner with lactulose she is a bit pale again. I'm thinking the lactulose is pulling too much water from her other tissue and is causing this, so I want to try miralax (or restoralax, as I'm in canada)
The Zeniquin is an antibiotic for urinary and tissue infections. (Vet said because there is some infection in her liver, this will help that) but I've read that Zeniquin isn't great for cats with liver issues as it is hard to process. But he did give her half a 25 mg tab/day, so it is a small dose. The metronidazole is an antibiotic for the GI tract. It acts differently then other antibiotics, in the way it is absorbed?.
I'm wondering if the antibiotics are slowing down her colon function? I think she should have pooped by now.
Is there a way to test her button muscle reflexes? I tried touching her butt and she flinches but her but hole muscles don't actual flinch. (Sorry for the graphics!!)
What are your thoughts?

73 hours later but Luna finally pooped!!!

3CatsMom said:

73 hours later but Luna finally pooped!!!

Click to expand...

Yay!

It was very exciting, thanks for the support! .

She was looking better yesterday. Pink in her ears, eyes and gums but this morning she was pale again...looking like anaemic again.
This is so worrisome, I don't actually know what's wrong with her.
An invoice says "diagnosis: colangiohepatitis" . The vet never once mentioned this verbally and from reading online, it doesn't seem to add up with her symptoms. :s.

What ARE her symptoms? Was her constipation the only thing wrong?  No vomiting or loss of appetite or even a little jaundice?   I'm guessing he's treating her with those two antibiotics first to see if the colangiohepatitis is being caused by the intestinal infection.  Let's hope it IS

BTW, did he do anything at all to actually treat her anemia?  Any B-12 shot, anything else?  How bad was it?  You said her RBCs were low, how about her HCT (sometimes called PCV)?

She is lethargic and her appetite has decreased a small amount today, compared to the past few days. (although she is still eating a good amount and she eats on her own).
When I noticed she was anaemic, prior to bringing her to the vet last Friday, I never noticed jaundice. Just very white eyes and mucus membranes, including gums. I still do not see any yellow in her.
As for vomiting and diarrhea...
Last Thursday, I started giving her canned tuna because that's when I had noticed that she wasn't herself and she had lost a lot of weight. (So tuna was all she had in her tummy) Friday morning she had a bit of diarrhea, no vomiting. I took her to the vet because that's when I noticed she was anaemic as well. Now, all my cats and dog are on a grain free, high quality kibble. Acana or Orijen)
While at the vet on IV, I went to visit her and they asked me to feed her Science diet. I did because I didn't have her food with me. But she ate on her own. We left some in a bowl for her when I left. They told me they had to force feed her! And that she had diarrhea and threw up in her cage. Now I honestly believe that happened due to the science diet food in particular to make her sick. It isn't grain free. Nor is it even a good quality food. The diarrhea I think is due to her probably not eating for a while, then eating straight tuna. And then science diet.
Since being home, (also considering the enema) yesterday her poop was soft, yet formed. No diarrhea since last Fri at the vet. Also no vomiting.
I will post her blood work.

Oh and to treat her anaemi, the vet didn't do anything. He offered me a vitamin supplement that was $35 but they didnt have it on hand. They were closed the following day and It took 3 days to get there. I picked up a multi vitamin for senior cats from my local pet store and have been giving her that.
She also hasn't pooped in over 24 hours again and I didn't give her the lactulose yesterday because her stool was soft.
Any thoughts on this?

OK, I see why he wasn't able to treat the anemia now.  As to the diarrhea and vomiting "in house" at the Vets, I agree that it was probably their food.

And as to her pooping schedule, I really don't have any ideas.  Was the amount yesterday pretty large, considering there hadn't been any for 3 days?  But remembering that she was probably fairly empty from the enema.  I wouldn't worry too much unless she doesn't  poop by the end of the day today.  But I would let the Vet know (tomorrow)  what is happening, how she perked up yesterday, now is lethargic again today .

I see her HCT is low, but I've seen a whole lot worse.  Some cats require transfusions.  Let's hope it doesn't come to that.    When's your next follow-up appointment? 

(BTW, I'll be leaving here shortly for the rest of the day so may not be too responsive until tomorrow)

for pink gums and moor poop

Thank you for the comments. I appreciate it.
I'll give her poop until tomorrow before worrying more. With a liver issue, 2 antibiotics, living in a secluded room and not feeling well, she may not have to poop till tomorrow. Plus she's had a lot more intake of fluids then actual good content. So she may not have enough to actually poop yet. Her poop yesterday was a good size.
Graphic pic of poop to follow, be warned lol. .
I contribute the shine to the lactulose and lube from the enema. Although the stool itself was very dark.

*intake of water higher then intake of actual food content. She urinates about 3-4 times a day, and its usually right after she eats.

Also, the vet said normally they would retest in 3 weeks, but we can follow up in 3 months because the vet believe she was doing much better. (The same time we were leaving after an enema and she was higher then a kite) .

hmmm, well I think I'd follow up sooner (with the Vet), IF she doesn't seem to improve.  You may not need to get more blood drawn, but was he going to order the B-12 shots for you to give, or are you just going to give her the OTC vitamins?  What about her liver?  Are you going to be giving her anything to try to help with that?  There are lots of meds for liver support, many of them OTC.  Sam-E, Vitamin E, Milk Thistle, or prescription Denamarin, which encompasses all those, I believe. 

They are closed today for Thanksgiving and we're closed yesterday as well.
She seems better again today. Eating a lot and very alert. She even played with the laser pointer today.
I let her roam the house for a bit yesterday, so there is a chance she pooped when she went downstairs but I don't know for sure. She hasn't pooped yet today.
The vet didn't order to mention a b 12 shot. I asked about vitamin supplements and then he said he'd order some for me.
The OTC supplements I have for her include most of the B vitamins, milk thistle, and a lot more. That's all I'm giving her as of now. I don't want to overload her system with too much. The lactulose, Zeniquin and metronidazole is already taking its toll on her. When the antibiotics are done, I will follow up with some probiotics for her.
I will call the vet tomorrowow to schedule a quicker follow up appointment. I might even go for a second opinion as i'm not overly confident with this current vet.

You can give probiotics WHILE you are giving antibiotics, just not at the same time of day.    We always do that, with our Vet's blessing. 

If  you do not have complete confidence in your Vet, then I would definitely look for another one.

Ok, I'll pick some up tomorrow. Thanks .

I took Luna to this place because I needed to get her in asap, so I found the closest bet that could take us right away. Our regular vet is a further drive then I wanted to put her through in that moment. The one vet I will see in there, is only in 2 days a week but I still don't want to put her through that's drive.
I am on the hunt for a more local and trusted vet for all 4 of my fur babies.