Cat urinating everywhere! Please help!

You were all so amazingly helpful before that I am coming back for more advice. My husband is about to lose it.

We got Poof (Mama cat) in June last year. She was an indoor cat that was kicked out and I couldn't handle that. We picked her up and brought her home. Come to find out she was pregnant. She had the kittens in July. The first month she was here she never peed anywhere but the litter box. Some time after the kittens were born she started peeing on towels if they were left on the floor. Never clothes left on the floor, only the towels. It has now gotten to the point where she pees on the towels, couches, and my bed. I take apart the couch, wash it, and she pees. I strip the bed, wash it, and she pees. We have her 2 kittens here with us along with another female. Poof is 1, Mooshie (other female) is 9 months, and Kittens are 7 months. We have 2 litter boxes that I clean constantly. She was spayed 3 weeks ago and I thought maybe that would change things, but it hasn't. I had her at the vet yesterday because she has eosinophilic granulomatous complex. I don't think that that would have anything to do with it. I don't know what to do. If I can't get her to stop she is going to have to go. I can't have every piece of furniture smelling like pee. My husband is ready to kick her out. Please help!!

Has Poof been checked for a UTI?  That's the number one reason why cats stop using their litter box regularly.  If not, take her to the vet as soon as possible - these can be very painful.  
[article="29715"]Feline Lower Urinary Tract Disease Flutd  [/article]
Sometimes this remains a problem even after a UTI is resolved because cats relate the box with the pain from trying to urinate.

 Check the article below for some ideas to resolve litter box problems.  You might find right off the bat that increasing the number of boxes does the trick.  The rule of thumb is one box per cat plus one.
[article="32366"]How To Solve Litterbox Problems In Cats The Ultimate Guide  [/article]
One thing that a lot of our members find useful is to try one of the Dr Elsey Previous Cat Attract Litter products.  The litter texture and a herbal additive bring many kitties back to the litter box.  You don't have to use the litter forever, just until training has been reestablished.  You can then gradually switch over to a regular litter.  Here is their website:  http://preciouscat.com/product/  

Another possibility is that that Poof is stressed.  The following articles might give you some insight:
[article="30307"]Is Your Cat Stressed Out  [/article][article="30316"]Six Surefire Strategies To Reduce Stress In Cats  [/article]
Whatever the cause of Poof's litter box avoidance, the use of a calming agent might help.  Below is some information on some of the calming agents available.  Although none of them work for every cat, all have been recommended by our members:

1. Feliway is available as a spray or as a diffuser.  It is based on a facial pheromone that cats emit when they are feeling content and happy.  Many of our members have had very good results with it, although it is important to realize that if you use the diffusers, they only cover 700 to 900 square feet.  Feliway's website is:  http://www.feliway.com/us/#redirected   It does tend to be rather expensive - several members have found amazon to be the cheapest source.

2. Composure is a calming supplement available as a treat or liquid that can be mixed into the food.  http://www.vetriscience.com/index.php?l=product_detail&p=9008103030   

3.  Calming collars contain calming pheromones.  Their effectiveness is based on the premise that a constant level of pheromone is available close to the cat's nose.  There are some concerns with these collars:  they often are coated with a powder that gets on everything, they may have a strong odor and some users have complained they are not effectively break-away.  Here's a link to the amazon page that lists some of the many available.  http://www.amazon.com/s/ref=nb_sb_noss_1?url=search-alias%3Daps&field-keywords=calming+collars+for+cats

4.  Bach's Floral Remedies (in particular Rescue Remedy) have helped many of our members.  http://www.bachcentre.com/centre/bfrani.htm

5.  Spirit Essences are also recommended by our members:  http://www.spiritessences.com/category-s/1876.htm

Another option, as a last resort is to ask your vet about medication. This is generally a last resort but we've had several members who have been able to control inappropriate urination with medication.    Medications include anti-depressants such as Prozac or anti-anxiety medications like valium, xanax or ativan.  The following article discusses the anti-anxiety medications. 
[article="30323"]Anti Anxiety Medication For Cats  [/article]
Another aspect of this situation is that it is very important to use an enzymatic cleaner that breaks down urine molecules.  Otherwise Poof's sensitive sense of smell will allow her to pick up on residual odor and that will attract her back to the site.  Nature's Miracle is often recommended for this purpose but there are many similar products on the market.

As you can see, there are a lot of things you can do before banishing poor little Poof.   Sending you vibes that you can figure something out.  

 Thank you for all the info. I will try whatever I can to fix whatever is wrong. I can't imagine having to give her up.

Here are a few more articles that may be useful in getting to the root of the problem.

http://www.thecatsite.com/a/how-to-choose-the-right-litterbox
http://www.thecatsite.com/a/how-to-choose-the-right-cat-litter
http://www.thecatsite.com/a/how-often-should-i-clean-the-litter-box
http://www.thecatsite.com/a/how-many-litterboxes-should-you-have
http://www.thecatsite.com/a/litter-box-maintenance
http://www.thecatsite.com/a/litter-box-location-secrets

Good luck sorting this out! I know it really can be very frustrating.

I'm kinda going through that with Maple right now. We had gotten her to the point where she went on towels but now trying to get her to use the litter box again. She was (with the help of a 30-gallon bin and 40# of Cat Attract litter) but now she has a UTI and is going on the pee pads that the litter bin sits on. So, not 100% back to square one, but close enough.

It will take a LOT of patience, a LOT of scooping, and a LOT of understanding on the part of your husband. Every time I scoop the box, I try to make sure Maple sees me do it so she knows it's clean. Not that I think you aren't keeping the box clean, but for some reason some cats get even more "litter box finicky" at some point.