Help Recover Kitten from paracetamol poisoning

She is back to life now  

Has your kitten seen a vet?

talkingpeanut said:

Has your kitten seen a vet?

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I agree completely, your kitty NEEDS to see a vet, ASAP.

Thanks for the interest... She is much better now eating, and sleeping but I need further help in her respect, Because Now I'm in love with her.
Her Story...
The long story in short....I found her in very bad condition 20/25 days ago....I treat her with doxycicline for few days, she survived, and became very intelligent & playful, I cannot afford her so I left her to a near by chicken shop, 4/5 days ago she found me in market and hold my foots, so I took her back at my place, and examine her, found her nose, jaws, throat, swollen and rashes on her body, she was very dirty and lazy and sleepy, So I begun her treatment by giving Doxy again, after 2 days when I found no effect, then I gave her deltacortil and Paracetamol mixed 100 mg for reducing fever and swollen at night, next morning I found her freeze, no eye blink no movement with high fever, I gave her one more time 100 mg paracetamol plus Doxi, I noticed she had not ate anything and not drink water whole day, Then I worried and I googled for her, O **** I gave her 200 mg paracetamol, where the fatal dose for kitten is 10 mg, I prayed to God, and Read verses upon her....Then God shows me the light of wisdom, I found ectylcyteine as antidote for paracetamol poising, I found it very difficultly appox after 24 hours of her poising, I'm feeling her condition like my own, I gave her antidote continuously all night  and rubbing her, awaking her, and warming her with my chest, next morning she opened her eye very poorly....drink some water, her ears, lips, gums became dark brown and bleeding nose and gums, I found that due to poising, her blood was burned and liver damaged, I consult a doctor in my neighbor as I need vitamin C for kitten, He advice me to give her Lysovit  B complex syrup. I gave her Lysovit plus doxi last night, and today she is much much better, she ate 250 gram chicken liver and minced breast piece today, and played with me, walked with me, also gone outside, do potty and urine well.........But I'm worrying for her internal damages, please tell me what things I gave her...I decided to take her for life because she fully trust me, love me, sleep with me, and she is v.v. intelligent, even she under stands what I want to say her in my language, amazingly she understands my mood.... I'm happy at the moment that God helps me in her survival and forgive me for my mistakes..
You peoples may think why I had not taken her to the Vet or Hospital, Because of my destitution state. My Kali is very patient, she wait for hours for her meals,   

She really DOES still need to go to a vet though to determine if there is any long-term damage that was caused. She might seem ok now but there could be permanent damage that was done.

I am sorry you and your kitty are going through this. I found this info on line

As little as 10 mg/kg is enough to kill a cat. It takes approximately 20-30 minutes for the drug to enter the bloodstream.

Ingestion either happens when well intentioned owners administer the medication to their cat either directly or indirectly administers another medication (such as cold and flu medications or cough syrup, which shouldn't happen unless a veterinarian has said it's okay to do) which has paracetamol in it. I should note, this is a common cause of paracetamol poisoning in humans too, and care must be taken when using more than one type of medication at a time, to make sure you are not doubling up. It is possible for a cat to eat paracetamol, but less common than with dogs as cats are much more discriminate in what they eat.

The medication can cause a life threatening condition known as "methemoglobinemia" (metHb) which is an increase in the production of methemoglobin, a form of haemoglobin which is unable to function as an oxygen carrier, resulting in a lack of oxygen to the organs and tissues.  Toxic levels of waste products of metabolism (known as metabolites) build up, causing liver failure. In addition to liver damage and methemoglobinemia, Heinz body anemia also occurs.

What are the symptoms of paracetamol poisoning in cats?

As we have noted, damage is threefold, the liver fails, the cat slowly asphyxiates (starved of oxygen) and anemia occurs due to Heinz body anemia.

Typical symptoms include:

• 
  Tongue and gums turn a chocolate brown colour due to the build up of methemoglobin.
• 
  Brown urine.
• 
  Difficulty breathing.
• 
  Loss of appetite.
• 
  Lethargy.
• 
  Vomiting.
• 
  Increased heart rate.
• 
  Swelling of the face and paws.
• 
  Ataxia  (unsteady gait).

As liver begins to fail, jaundice (yellowing of the skin and gums) and mental disturbances may occur.

How is it diagnosed?

A history of exposure to the medication, plus accompanying symptoms such as brown coloured gums. Your veterinarian may wish to run some tests to determine the extent of the damage. These may include complete blood count and biochemical profile to look for methemoglobinemia and evaluate liver enzymes.

How is it treated?

The faster your cat is treated, the better. If ingestion is recent then vomiting will be induced followed by administration of activated charcoal to absorb the toxins.

• 
  N-acetylcysteine (NAC) is a form of the amino acid "cysteine". This amino acid assists in the detoxification and elimination of paracetamol which protects further damage to the liver.
• 
  Vitamin C can help speed up the removal of paracetamol.
• 
  Blood transfusions may be required for cats with severe anemia.
• 
  Oxygen therapy.
• 
  Fluid therapy.

Prognosis depends on how quickly your cat is treated after ingestion and how much medication was consumed.

Never administer medications to your cat without veterinary supervision. Over the counter or prescription painkillers should never be given to cats as most of them are unsuitable and can result in death. If you think your cat is in pain, he should be taken to a veterinarian immediately.

I found this info, sadly the outlook is not very good https://www.vetstream.com/felis/Content/Disease/dis00287 . I am praying for Kali. All you can do now is love her and make her comfortable. 

Yes I understand but can't afford Vet...
I decided not to gave her medicine anymore

I think the power of love and prayer resurrected her.
she is awakened now showing me her neck,felling sore throat
 

What kind or breed she is ???

My-Kali said:

 
What kind or breed she is ???

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are you referring to the cat in my avatar? That is Midi (Midnight) he is a run of the mill domestic short hair. Please let us know how Kali is making out.

I like black cats..
she is sitting alongside my foots, looking here n there actively, asking for more food, urinate few minutes ago...........try to play but feel weakness or pain, no voice or very low mouth opening

Zed Xyzed said:

 
I found this info, sadly the outlook is not very good https://www.vetstream.com/felis/Content/Disease/dis00287 . I am praying for Kali. All you can do now is love her and make her comfortable. 

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Link not opening in chrome yet

My-Kali said:

 
Link not opening in chrome yet

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Here is a summary of the link 

Outcomes

Prognosis

• If clinical signs are present, prognosis is poor.
• Prognosis becomes more guarded as time since ingestion increases.
• After 8 hours, treatment is unlikely to be effective and death is inevitable if a fatal dose has been consumed.

Expected response to treatment

• Plasma acetaminophen/paracetamol level, if the test is available, should be estimated urgently in any animal that has, or is suspected of having, acetaminophen/paracetamol poisoning.
• PT >100 seconds, a rising PT between days 3 and 4, or severe hepatic encephalopathy are poor prognostic indications.
• Urea and creatinine concentrations should be measured to detect renal failure.
• Blood glucose should be monitored as patients may become hyper or hypoglycemic.
• An early rise in liver transaminase enzymes (ALT, AST) is an indicator of potentially serious hepatotoxicity.

Reasons for treatment failure

• Excessive quantity of acetaminophen/paracetamol ingested.
• Delay in treatment until clinical signs are well developed, by which time irreversible damage has occurred.
• Non-aggressive management or poor supportive care.

Zed Xyzed said:

 
are you referring to the cat in my avatar? That is Midi (Midnight) he is a run of the mill domestic short hair. Please let us know how Kali is making out.

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sitting on my lap, no fever, normal breathing, calm,  looking okay but not cleaning here self

Zed Xyzed said:

 
Here is a summary of the link 

Outcomes

Prognosis

• If clinical signs are present, prognosis is poor.
• Prognosis becomes more guarded as time since ingestion increases.
• After 8 hours, treatment is unlikely to be effective and death is inevitable if a fatal dose has been consumed.

Expected response to treatment

• Plasma acetaminophen/paracetamol level, if the test is available, should be estimated urgently in any animal that has, or is suspected of having, acetaminophen/paracetamol poisoning.
• PT >100 seconds, a rising PT between days 3 and 4, or severe hepatic encephalopathy are poor prognostic indications.
• Urea and creatinine concentrations should be measured to detect renal failure.
• Blood glucose should be monitored as patients may become hyper or hypoglycemic.
• An early rise in liver transaminase enzymes (ALT, AST) is an indicator of potentially serious hepatotoxicity.

Reasons for treatment failure

• Excessive quantity of acetaminophen/paracetamol ingested.
• Delay in treatment until clinical signs are well developed, by which time irreversible damage has occurred.
• Non-aggressive management or poor supportive care.

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Thanks, v. useful information, but I think, as kittens are under developing age,  some foods/supplements/drugs should have power to restore damaged organ, because of the process is under DNA and in developing state

I am sorry everything I have read leads me to believe that Kali will not survive this. Show her lots of love  and try to comfort her and ease her passing. I am sorry that you and Kali are going through this.  Praying for a miracle 

This thread is heartbreaking! Poor kitty. Are you sure you cannot take her to a vet? She is in need of immediate care!

I'm trying my best to present her in vet hospital as soon as possible....
at the moment her tongue and cheeks are restoring there pink color with dark patches.... 
her eyes glow is somehow returned, 

Zed Xyzed said:

 
Here is a summary of the link 

Outcomes

Prognosis

• If clinical signs are present, prognosis is poor.
• Prognosis becomes more guarded as time since ingestion increases.
• After 8 hours, treatment is unlikely to be effective and death is inevitable if a fatal dose has been consumed.

Expected response to treatment

• Plasma acetaminophen/paracetamol level, if the test is available, should be estimated urgently in any animal that has, or is suspected of having, acetaminophen/paracetamol poisoning.
• PT >100 seconds, a rising PT between days 3 and 4, or severe hepatic encephalopathy are poor prognostic indications.
• Urea and creatinine concentrations should be measured to detect renal failure.
• Blood glucose should be monitored as patients may become hyper or hypoglycemic.
• An early rise in liver transaminase enzymes (ALT, AST) is an indicator of potentially serious hepatotoxicity.

Reasons for treatment failure

• Excessive quantity of acetaminophen/paracetamol ingested.
• Delay in treatment until clinical signs are well developed, by which time irreversible damage has occurred.
• Non-aggressive management or poor supportive care.

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hey ! there, in the prognosis the 3rd line said (after 8 hours, treatment is unlikely to be effective and death is inevitable if a fatal dose has been consumed) I gave her antidote after 20 hours, she is almost motionless or very drowsy in this period but at the moment she is also looking at the laptop screen, lying in my lap, after eating some raw liver, sucking my fingers, but looking weak and tense

27 hours after posting for help in this from..........My Kali is sitting on my lap and looking on the screen

   

pray for my love

tomorrow I shall post some images

My-Kali said:

 
27 hours after posting for help in this from..........My Kali is sitting on my lap and looking on the screen

 

 

pray for my love

tomorrow I shall post some images

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This is wonderful news.   I'm so glad she's feeling better!