10 yr old cat with chronic diarrhea (diagnosed with Clostridium perfenges)

My 10 yr old cat has chronic diarrhea for about 6 months now.  He has been on S. boulardii and L-glutamine for about a week with no improvement.

I have gone the "vet recommendations" route which includes Flagyl, Prednisolone, Clavamox, Science Diet Z/D food, Rx clay. None of it improved his

condition. 

I have also have been giving him Bio-Sponge (Spectite clay, intestinal absorbent), Green food (algae mixture), Goats Milk Colostrum powder, probiotic,

digestive enzymes, Cosequin. and pumpkin flakes.  He is on a high quality non grain, low carb food, both wet and dry.

His poop ranges from liquid, to semi formed, to a little of each in one movement.  His appetite is okay, and he hasn't lost any weight in spite of the long

term diarrhea.  Actually he is very overweight, and has always been a "couch potato" of sorts.  Never been able to get his weight down to a healthy

range in previous attempts.

I read some old threads from a few people who had success using S. boulardii to stop their cat's diarrhea.  I welcome suggestions from fellow members on this site.  I am a new member, and this is my first posting.   

I'm having some of this same issues with my kitten. She has on and off diarrhea/soft stools and I've taking her to think vet twice for it. They put her on meteonidazole for her tummy and some probiotics. I know how frustrating it can be to deal with this especially when you feel like you are doing all that you can. I give my kitty about a tablespoon of purred pumpkin as a supplement and and going to start putting her on probiotics daily. Check with your vet but pumpkin might help your baby too.

For CF, I too tried the S. Boulardii route without success. We then opted to treat with Tylan (I used the powder and put it into size 3 (?) gel capsules. This paired with putting the cat on a boiled chicken only diet for 5 days and then transitioning to a canned-only diet (Nature's Variety Instinct Turkey formula) was what finally corrected the diarrhea.

I can't remember how long we used the Tylan; but, I want to say it was for at least 2 weeks, though I want to say it was longer.

We also retested after treatment to make sure it was gone.

I am trying the S. Boulardii because it is supposed to specifically control/cure Clostridium perfenges, which Scooter tested positive for, on a PCR test.       I am giving him 1/2 of a Jarrow (5 billion) strength capsule 2x a day; based on info given by other members who were treating for the same problem.

However, because he weighs close to 21#, I'm wondering if he should be receiving a larger dose?  He has been on this dosage for a week, without 

any drastic improvement.  He is on Wuruva, Pride(by Instinct), and Wellness wet food; along with some Orajen/Acana dry.  All of my cats are indoor,

only.

He is very timid, and stresses easily.  So, I try to gets any "meds" into him via food, or syringe, rather than gel caps.  I used Tylan on a previous cat,

without success.  Because it is so bitter, gel caps are really the only way to dose it.

Hopefully, someone can give me feedback (from past experience) as to whether  he is receiving the right dosage for his size.  Thanks for all feedback!

Sorry, I had a typo in my response. Instead of CF, I meant CP, for the Clostrifium Perfringens.

I used the Jarrow as well. We tried it for several weeks before switching to Tylan, which is what finally did the job.

I definitely understand wanting to try medicating a different way, especially with a more difficult kitty.

I know there is at least one other post that talks about using s. Boulardii. Let me see if I can get you the link.

Here is the thread so was thinking about. The S. Boulardii is mostly used to treat C. Diff; but, I know there is information in regards to Clostridium Prefringens.

http://www.thecatsite.com/t/283161/saccharomyces-boulardii-use-for-diarrhea-and-gi-disease-incl-ibd

That is food poisoning.

Your veterinarian may prescribe a week’s worth of oral antibiotics if the Clostridium perfringens toxin is found. Cats that need to be treated for long-term cases of diarrhea may need to be given antibiotics for a longer period of time.

Dietary management is also helpful in the treatment of this condition. High-fiber diets and diets formulated with prebiotic and probiotic ingredients (like lactobacillus) can help to balance and maintain the intestinal flora of the gastrointestinal trac

Hey. When all vet issues have been ruled out i always recommend commercial raw food. My cat gets diarrhea whenever he eats dry or wet food. He is doing fine on primal frozen raw nuggets. Its expensive and inconvenient but it is worth curing diarrhea.

My 11 year old cat Callie was recently diagnosed with Clostridium on 4/6/2018. The vet put her on a powder combination of Biotec/clay/tylan. I mix 1/16th teaspoon of this powder with 1/16th of powdered sugar into some can cat food. So far she is starting to get her appetite back (very slowly) for she is very wise to the medicine, once I am able to get her to eat the food with the medicine in it I also give her extra wet food (I've been having to buy several different can foods to keep enticing her to continue to eat). Unfortunately, her stool isn't getting better yet, but it's only been 4 days. It's too bad our furbabies can't talk. It's so frustrating to have to hope the vet is right on what medicine will work!