Big move resulted in aggression. HELP!

I have done everything I can think of short of dosing my cat with prescription grade anti anxiety medication. I have recently moved in with my boyfriend who my cat of over a year has known and until now had no issues with. Since we moved in together she has become skittish, aggressive, and reclusive. Going so far as to hiss, scratch, and bite my boyfriend, enough to break skin. I'm doing everything possible to make her comfortable, spending time alone with her, feeding her, giving her new toys, blankets, treats, and pet store variety anti anxiety and calming meds to no avail. The last thing i want to do is take her for a prescription that could leave her dull and lifeless, but I'm running out of options. If anyone has any tricks or suggestions i would be so grateful. 

Is there a way you can give her a room of her own for awhile?  She doesnt have to stay there ALL the time, but if she has a place that she feels SAFE, where her bed, litter box and food are, and where the door is closed and no one but you enters, that should help her calm down.  Everything in her life has changed and she is feeling very stressed.  Cats like SCHEDULE and SAMENESS and ROUTINE, and everything about her life has been turned upside down.  If there is a place where she could feel safe, where you could make her life predictable for awhile, she will begin to relax.  I can remember feeling like that when my mother married my stepfather when I was 8 years old.  We left my aunt and uncle's house, where I was very happy, traveled many miles to New Hampshire, then got settled in another house, I had to change schools, etc. and I hated my stepfather for it!!  Your cat is not all that different an an 8-year-old girl.  It will take time, but treating her like one would treat new cat, giving her a place to call her own, keeping her routine fairly stable, will go a long way into helping her settle into the change in her life.  Good luck, and let us know how she is doing when you get her settled in her own room.

I've tried to give her her own space but. I'm in a one bedroom apartment now, and I don't have anywhere besides a closet that has a closed door for her to be completely alone. When I brought her to my previous house from the shelter I did just that and within a week or two she was fine. The problem is when my boyfriend is out of the apartment she feels comfortable and wanders the apartment at will, as if nothing has changed. She won't use her cat travel basket as her own space and no matter where she is she can hear him. I'm trying so hard to make a peace between them, because this isn't easy on her. I'm just so lost as to what my options are because I have taken all the normal and expected steps to integrate her to this environment.

How about getting a large dog crate, draping it with a sheet or better yet a quit on 3 sides and setting up a bed and litter box for her in there.  You could put the crate in the living room or bedroom, somewhere out of the way, and put her in there when your boyfriend is home, since he seems to be the source of her anxiety.  He can stay away from the crate and she will feel safe there.  I have used ativan on cats (with my vet's permission and direction) 1/8 of a 1 mg. tablet.  It is odorless and tasteless and dissolves in water.  I had to use it on my feral Grey Boy (see his journey under my signature) every 5 days when he had to go to the vet for a bandage change.  I could not pill him, and the vet tranquilizer, which is the same family as ativan, wouldnt fool him and he would spit it out if I hid it in food.  He actually got 1/4 of a 1 mg. ativan because he was a big cat, and I would crush it into powder and then put it on a piece of turkey bacon and roll it up.  He would gobble it down and pretty soon he would climb into his laundry basket and pretty much go to sleep, so I could put a second laundry basket on top and hitch it with zip ties and then haul him to the vet like that.  We would cut the zip ties on one side and the vet would give him a quick shot and he would go to sleep and go get his bandages changed.  Then I would take him home, still out cold, in the laundry basket, take the second one off the top, and let him wake up in his familiar place. 

I have used the smaller dose on a couple of the other cats in certain situations and it does relieve their anxiety.  It is particularly good on ferals.