Cat anxiety/stress unusual behavior.

Within the last two months my youngest cat George has gotten up at about 3am every night to play.  He Meows extremely loud and knows things off my night stand.  His older brother Roy never is up that late or gets up that late.  If I close my door he scratches at the carpet and the door.  I started to put in the bathroom where there is water, his litter box and its very warm and comfortable. He didn't seem to mind it.  But when I would let him out in the morning he would meow constantly until I left for work.  He always slept fine inthe bathroom until this week.  He was so anxious and upset he rubbed his face under the door rubbing his face completely raw of fur to the point it bled.

I had read about getting a calming collar to see if that would help his behaviour because I didn't want him to hurt himself.  He was good for about two days, then again last night he was meowing really loud and wouldn't stop.  I tried putting him in the bathroom but he would rattle the door with his paws and rubbed his face again so I didn't keep him there long.  I am not sure what to do because I need to be able to sleep.  I don't have anywhere else to put him and I don't want him to hurt himself.

I am not sure what to do because he is hurting himself and I am not sleeping.

Any advice is appreciated.

Cat's do not do well being confined to a single room they dislike it because by nature they are very curious creatures a shut door to them tells them there is something far better on the other side. First of all I would try feliway to calm him lucky for me I have never had to use it but I have heard many success stories. It isn't a quick fix though it takes a good week or so to build up. You can also get calming cat treats to feed which may help. Secondly let him have free roam of the house but when he is meowing IGNORE him completely do not move don't open your eyes just lay there as if you are still asleep. He's used to getting a reaction so it will take a while but eventually he will learn he won't get the reaction he wants and move on.

3am is not late to a cat. if he is 2 or 3 he is not a kitten anymore and is acting like a normal cat which sleeps during the day.

I think the calming treats mentioned would be your best bet as mentioned above. I've had good luck with them and maybe after a while he'll get used to sleeping and not need them anymore! Thank you for trying to get him help, I know it's awfully frustrating at times. Good luck and tell us how it turns out!

We have a couple of excellent cat behavior articles on this very topic. These deal with stress/anxiety -

How to Tell if Your Cat is Stressed Out

Potential Stressors in Cats - The Ultimate Checklist

And this one offers several solutions - 

Six Surefire Strategies to Reduce Stress in Cats

Also, check out this one - 

Cats and Night Crazies!  is more specifically about night time activities.

If your cat is very active at night, you should first try playing more during the day. Your cat is not necessarily stressed, he is just being a cat! Playing more in the day will help use up some of his energy... Remember cats sleep about 75% of the time! Get some toys that you can play with him with, depending what he likes-eg balls, mice, or toys on string that you can drag around and get him to chase. Make sure he has climbing furniture, and a high retreat somewhere where he can get away from other cats if he wants to. Scratching furniture is also important. Try to have a couple of good play times just devoted to him during the day. Think of it as similar to walking a dog - cats need this interactive play time to prevent boredom. This may be a little more work, but is better than medicating your cat needlessly when there is likely nothing wrong.
Having said that, if the night time behaviour continues get him checked by your vet to rule out organic diseases that may be affecting his sleep cycle. Do not lock Jim up at night but let him have the run of the house if this is what he has always done. Otherwise he will wonder why he is being punished.
Good luck & geek free to contact the me again if you wish.

Him, not Jim. Sorry!

Damn you auto correct.... Feel free not geek free... *sigh*

What @DrCat has said is pretty much hitting the nail on the head I hope your kitty is adjusting now and that the advice you have received has helped you work out his behavior 

Even cats don't see in pitch black, so when I put really good curtains to windows so that room became completely pitch black, mine started to sleep when I did sleep, but also I found out that I could sleep much better because of complete darkness, it was much easier to fell asleep too.

Also curtains seemed to cut a heat during the summer days and cold at winter nights, so there was other benefits from them.

So that worked for me.