Calcivirus 8 moth old kitten - neurological issues after steroid, we are loosing the battle!, and ad

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kimagavin

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~~~~Urgent advice needed for very sick 8 month old kitten – Calci virus and neurological damage from steroid injection!! We homed Otis from a rescue centre when he was 10 weeks old, he is an amazing little cat with the sweetest calmest, confident nature. At the foster home he was living with 10 other cats all of different ages and there was some health issues with some of the other residents.

When he came to live with us and our 2 other cats aged 4, he had no health issues at all, and He had all of his kitten injections at around 14 weeks. He has always had a very health appetite and eats well with the other 2 cats at set meal times in the morning and evening, food is down for all 3 cats all day, so they can have a nibble whenever they feel like it. Otis has always loved his food, especially fresh meat such as ham or chicken. Our other 2 cats can go outside when we let them, but Otis has not yet left the house 3 weeks ago Otis was not himself, we noticed on the Friday morning he was quiet but he came down to breakfast, by the evening he was still a lot calmer but still ate dinner. On sat he was really subdued and we made a massive fuss of him and checked he was using the litter tray as normal no upset tummy issues. By sat night we were really worried he could barely open his eyes and was curled up in a ball,

First thing on Sunday we rushed him to an Emergency vets, not our usually vet as they were closed. We saw a young vet who checked him over and confirmed that he had a really high temperature, swollen glands to the neck and bad breath, she suspected he had a virus of some kind and advised us to go see our own vet on the Monday, she gave him a steroid injection to help with the fever and a 24hr hr. antibiotic. We took him home and kept him comfortable. On The Monday morning we took him to the vets first thing, vet checked over again and had the faxed notes from the emergency vet on Sunday, he was still running a very high temp, and she believed also he was trying to fight a virus of some sort, she prescribed him Loxicom oral with the syringe and advised on the correct dosage, she also gave us antibiotics for any secondary infections that might come along, we needed to look after him keep him fed and comfortable and see how the week went for him.

At this point Otis weighted 2.7kg We saw some improvement this week, he ate, toileted and seemed to be picking up by the Thursday night, still very sleepy not his usual self but better. On Friday we returned home from work to find him waiting for us but with huge dilated eyes, moaning and walking painfully and wobbly on the back legs, he looked like he had stroke and he was completely blind and disoriented. We had a terrible night with him he seemed afraid of the dark jumpy and scared. First thing sat we took him straight back to the vet, we saw the same vet as the Monday, he is now very tender, we can barely touch him without him screaming, vet checks over eyes and temp, his temperature is now back to normal. Poor Otis cannot see a thing, vet claims she suspects him to have FIP due to the slightly swollen stomach, eye hemeriage and the tenderness of limps, she takes bloods, warns us its fatal and we will have results on the coming Monday, she also tells us to be prepared for the worse as he is case book FIP. We left with antibiotic drops for his eyes and told to continue with the Loxicom.

All weekend we cared for him, drops to eyes 3 times a day, helping him to toilet food act, we were devastated and convinced we would be putting him to sleep on the Monday. Back to vets on Monday, Otis has now developed a sneeze, and congestion, eyes somewhat improved, and his vision if back slightly. We saw a different vet on the Monday, the day we thought would be his last.

Vet gave him the all clear on the blood s claimed he was clear for FIV, FELV that his bloods, and kidney function good, however the results did indicate he had been exposed to Calcivirus. His illness has been a mystery because it seems now that he has some sort of Neurological issue, he has an inch in the tail that cannot be touched as it causes him great pain and the front right paw seems to be lame, vet advised to try him for a day without the loxixom and see how he responds. We booked a follow up visit the following week after being advised that the cat was the only one who could fight the virus and we need to keep him calm and content to see if the nerves heal in the tail and the poor. We left feeling that we would fight this virus and he could heal from the neurolcal issues, he is eating fine at this point loves his food in fact drinking plenty of water and using the tray, we have had no vomit, not diareah at this point.

We have a good week with him he moves around a little, pleased to see us home, still having eye drops, resting, but his tail is very tender and his hind legs are week. Fast forward to the weekend, he stops eating, he is still congested, sneezing stops, we spend hours trying to tempt him but he’s not interested in anything other than water. We take him to vets on Monday he is very weak discuss issue for the last 24 hrs not really interested in food but drinking lots of water. Vet believed Loxicom is the issue tells us to stop giving the daily dose as it may make his stomach sick, give him a steroid pick me Up1, meant to boost his metabolic rate, kick start appetite back, so he will eat to get the strength up. We leave take him home, within 1 hr he is panting swaying head, heart rate super-fast and we thought he was going to die. We spent all night up with him soothing him giving him water, very next day call the vet in the morning tell him what has happened vet now thinks that he has had a reaction that he hoped would have helped with the steroid injection, I leave work early afternoon to be home with him and he has vomited, he is very weak and hiding, this is not like his behaviour at all! He wants to drink water often.

On the evening he seems to be interested in food smells meats, and pouches. I blend this up and make chicken broth fresh and we start syringing this and kitten milk into the evening. On wed morning he has some improvement, we continue with the syringe feeding, milk, broths and food, I researched vitamin c and Lysine he now has some supplements in the syringe food. This morning he is really poorly again, can barely walk and sitting on his front, we have another vet appointment this evening. I have said to partner no more Steroids and intrusive drugs, his little body can’t handle it, if we are to get him over this nutrition is the only way.

Are we fighting a losing battle, he wants to eat but is just falls out of his mouth, his interest is there! Has anyone had anything similar with the neurotically issue after or during a virus, is it the steroid, was it his high fever, is his body given up, his sneezing and wheezing is practically gone, but when he tries to eat it sounds like gurgling is this the issue with swallowing. If we think we have a chance we will keep at the syringe feeding and giving all the care and TLC under the sun if we can fight this, we love him so much, he is our little man, and the care we are giving just doesn’t seem enough. Please is anyone has any advice???
 

stephenq

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Hi there,

This is horrible.  I'm not a vet and can't diagnose this, but I and others can make suggestions based on our experiences.  Did the vet rule out Distemper (Feline Panleukopenia Virus) ?  I am going to link you to an article below.

Sadly it also sounds like it could be FIP as your Vet suggested, which tragically is fatal, and the effusive type (fluids in the abdomen) fairly rapidly so, and in the effuse type usually the best thing to do is humanely euthanize.   There is no specific test for FIP (you can test for coronavirus but lots of cats test positive for this and don't have and will never have FIP)  Diagnosis is usually done based on symptoms.

http://www.petmd.com/cat/conditions/infectious-parasitic/c_ct_feline_panleukopenia

And an article on FIP. http://www.vet.cornell.edu/FHC/health_resources/brochure_ftp.cfm

I'm so sorry for you and your kitten.

Stephen
 

catpack

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Just wanted to share

One of my 2-yr-olds (Tyson) came down with a horrible case of Calicivirus when he was 9 mo old. It was so bad that he developed "blisters" on his mouth/nose in a 2 hr time period and all the skin on his mouth/nose sloughed off 6 hrs after the blisters formed. He spiked a fever of 106.9 (suffered brain damage as a result) and developed a mucus plug that sent him into renal failure.

He pulled through all that; but still was very sick. About 5 days after the illness on set, he suffered a stroke-like episode, losing function to his rear legs and acting like he was drunk (for lack of better explanation.)

He was on a combination of Famciclovir, Doxycycline and Prednisolone for 3.5 months before he was completely cleared of the virus.

I also want to note that Tyson's 4 litter mates got Calici as well; but, only developed 1 ulcer a piece. No fevers. No other cat in the house became sick.

Tyson is doing well now; though will never return to his "Pre-Calici" self. He is FIV/FeLV negative; but, we know that his immune system is not normal. Anytime he gets sick, it takes longer for him to recover.

Also, Tyson regained use of his legs, though his gate in not 100% normal.
 
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kimagavin

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Hi Stephen

Thanks for the reply.

Vet really doesn think it is FIP as he has no visuable fluid issues inside, and his blood levels suggest he has no immune issues such as FIP, plus the systems for FIP are not really that similar to what he is suffering with,

the article on FPV is interesting as it suggests that this virus can cause infamination of the brain, which would suggest the neurological issues we are seeing!

If that is the case then with TLC and syringe feeding we may be able to fight it with him?

Are you able to advise at all on how much food we should be getting doen him in the syringe daily, to insure we are keeping his energy where it needs to be?

Many thanks

Kim
 

ritz

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I have nothing to add--only my vibes and prayers for you and your kitty.
 
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kimagavin

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Hi Catpick

Thanks for you reply, the drugs you mentioned ~~Famciclovir, Doxycycline and Prednisolone are these all steroids, what weight was your little quy when he got ill?

Otis is only 2.5 at the moment, not sure he can handle any medication.

With the grunting when Otis tries to eat, I wonder about blisters in his mouth and throat, vet mentioned his glands to his neck feel swollen?

Thanks

Kim
 

catpack

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Famciclovir is an antiviral
Doxycycline is an antibiotic
Prednisolone is a steroid.

I'm not sure of Tyson's weight at the time; but I figure around 9 lbs or so.

I assume your guy is 2.5 kg (or around 5.5 lbs?)

We have used these medications on kittens as young as 3-4 months of age. But, definitely consult with your vet.

Also, we did an upper respiratory panel on Tyson to get a true diagnosis. In addition to the Calicivirus, he also had mycoplasma (another viral infection.)
 
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kimagavin

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Thank you everyone for your kind replies.

I'm off to the vet in an hour with little Otis, not sure how is going to be when I get home from work, I hate leaving him at the moment, but there is only so much time I can take from work and he has been ill for 3 weeks now.

I'm not convinced its FIP hes missing some crucial symptons like upset tummy and the bloated belly, he has most certainly had 1 on the kitty viruses.

has anyone had an experience of syringe feeding, how much food do we have to get down him?

Many thanks

Kim
 

vball91

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Here is a good thread on syringe feeding. It also has a video that shows how to do it properly. http://www.thecatsite.com/t/227858/syringe-feeding-lucky-video-if-your-cat-is-not-eating

You want to aim for his normal caloric intake. For most cats that's a full can (5.5 oz in US) of a high calorie food. It will take several small feedings over the course of a day. Hill's a/d is a good food for syringe feeding (good consistency and high in calories).
 
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kimagavin

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Thought I would update all you caring cat lovers.

We took Otis to the vets last night, a check up to discuss the last few days, and the bad night he had on Monday with the steroids injection.

Vet sat us down and told us that he had called a friend who was one of the top feline specialists in Ireland, he told us some very bad news indeed.

We were right back 2 weeks ago!, the specialist had looked over the medical notes history and reactions in his body even the bloods, she is almost certain, that he has DRY FIP!.

We couldn't take it in at the time, ... he pointed out since he last saw Otis, he has platlets at the back of his eyes, and his ears are yellow, his throut glands are up with is now leaning towards Lymph node issues,all these are apparent final signs of the last stages of FIP,

He discussed the next few days, Vet knows that we have already heavily researched FIP and know it is a matter of time, We are absolutely devastated.!!!!

Otis had a vitamin shot and we were told to take him home give him the syringe food still and lots of TLC, we only have to get through work today, and we can spend the weekend with him and say goodbye.

He fought the syringe food last night, he wanted some normal food but couldn't eat it himself, the other two kitties we have are acting up as well, Bella the 5 year old female and Otis have a very strong bond, she constantly mothers him, and she is really upset, its like they know he doesn't have long.

Otis came to bed with us last night, he wanted cuddles and kisses under the duvet, just like he always has, issue is he couldn't stay rested for long, - we had about 3 hrs sleep again last night, we think he is slightly worse again this morning, he can still move around, up and down the stairs, get to the litter tray and even attempted breakfast, we gave him some syringe food, but didn't push to much on him as he was struggling!

My partner is still not convinced its dry FIP as we cannot actually say for certain until he is dead.. its too late then isn't it, !,

He wants to hot the syringe food regularly this weekend for 48 hrs and then decide on Monday if we are going to say goodbye, at this point he can still be picked up and wants to be around us, he still loves us at this stage, and I'm petrified of when he withdrawls from us, and cant move, and go to the toilet, I'm just hoping it doesn't happen this weekend.

Are we being cruel dragging this out, he still seems to want to fight, ! - will the nutrition help in just 48 hrs he has been so weak, my partner had looked up his signs and is convinced that he has suffered a nasty virus, brain issues from the fever and steroid injections, stomach upset from the loxicom, and is now so weak that we need to feed the syringe to get his energy back to fight it.

Can any one offer any advise, have they been where we are ?
 

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My heart goes out to you, I have fought FIP too and know what you are going through. It is true that you cannot tell for sure till it is over, but after a while the symptoms become fairly definite, and anyway, the only thing that really matters is the cat's quality of life, whatever the disease. Only you can tell when he has had enough, and I think that probably you know that a weekend of loving and being with him will tell you if that time has come. I am truly very sorry for you all.
 

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I'm very sad for all of you.  I don't know about this drug's availability or its cost, and I don't want to give you false hope but there is a new drug that has been approved in the US by the FDA for off label use in the dry form only of FIP and has significantly lengthened the lives of at east some of the cats who received it.

I'm quoting from my own post in a previous thread on the subject:

The April issue of Cat Fancy magazine discusses a new treatment for the non-effusive only version of FIP. 

There is a new USDA approved off label drug (Polyprenyl immunostimulant (PI)) for the treatment of the dry version of FIP that has prolonged a significant number of cat's lives, and is discussed at length in the April issue of Cat Fancy magazine. An online article that discusses this is at http://www.catchannel.com/catalyst/new-cat-fip-treatment.aspx

A more detailed article is at http://www.vetmed.ucdavis.edu/ccah/...g photo-heading-blurb, optional right col.cfm

The original thread is here.

http://www.thecatsite.com/t/273318/new-treatment-for-fip-dry-non-effusive-version-only
 
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kimagavin

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our little boy Otis was put to sleep this morning.
he deteriorated very quickly last night, became fully jaundice and could walk, he was whimpering and moaning and he must have been in a lot of pain.

he went downhill so rapidly we took him first thing to end the suffering.

our heart is broken... We loved and cared for him so much,
 
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