Duralactin/Microlactin for arthritis, stomatitis, IBD & other chronic inflammatory conditions

I just wanted to start a new thread so if anyone is looking for information they can find this easier than in Munchie's thread.   For anyone not familiar with my Munchie's story he has severe hip dysplasia in one hip with moderate to severe dysplasia in the other hip with arthritis in both hips and both knees (he had bilateral patella surgery), and then he has severe arthritis in one of his front legs.  My vet's recommendation was to euthanize, but I wasn't ready as he is happy, purrs all the time and still has a good appetite, so I chose to research and do whatever I could to help my boy.  I started him on Duralactin (pet version of Microlactin) about a week ago from an old tube I had from a prior herpes kitty, in the pastey tube, it lasted me one week.  You give 2.5ml's twice a day.  It has lysine in it as well as Omega's, the capsule form just has the Microlactin in it.  I really think it is making a world of difference in Munchie after just one week.  He is a lot happier, more active, going down the stairs (which he has avoided unless he thinks I am taking him to the vet), he isn't limping as badly and is jumping on furniture more.  I am excited to try it with DeeJay my 14 & 1/2 year old severely arthritic kitty.  I looked at every health food store in my town and they all gave me blank stares when I asked about it.  So that is why we are ordering it.  My dad (retired vet) can't even get the Duralactin capsules or paste for any cheaper than I can buy them online at his cost.  With 2 kitties that would be $12-14 per 10 days which would add up awful fast. 

If any one is interested in the microlactin.  Swanson's has the human powder on sale right now, I am getting a jar that will last both of my cats 140 days for $14.78 including shipping.  If you just have 1 cat it will last 280 days.  https://www.swansonvitamins.com/swanson-ultra-microlactin-powder-4-9-oz-140-grams-pwdr    I am going to give each cat 1/8th teaspoon twice a day which is about 250mg twice a day.  The Duralactin (which is the pet brand of Microlactin) capsules and the paste have about 200mg per serving.  They recommend 1 capsule twice day for cats under 10# and 1 capsule in am and 2 in pm for cats over 10# so I figure that is about the right dose.  My husband is seriously considering starting to take it for his joints as well.

Here are a couple of 'kitty' links about Duralactin:

http://www.vetinfo.com/cat-arthritis-duralactin.html

http://www.vpl.com/literature/pdfs/...chure_Consumer Brochure_300512415_12-0345.pdf

 From Duralactin's website:  http://www.duralactin.com/product.htm

What is Inflammation:

Inflammation is a multi-faceted primarily cellular response to injury. After an inflammatory stimulus, neutrophils are activated and migrate to the source of the insult. Neutrophils release a number of substances, including digestive enzymes and inflammatory mediators. Some of these mediators result in arachidonic acid metabolism, which is further converted by cyclooxygenase (COX) and lipoxygenase (LOX) into inflammatory prostaglandins and other components. This results in inflammation and ultimately discomfort.  

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      What Role do Cytokines and Neutrophils play in INFLAMMATION?

Inflammation is triggered by chemical mediators (histamine, serotonin, etc.) and mediators from white blood cells, especially neutrophils (prostaglandins, leukotrienes, lysosomal enzymes, etc.). Injured cells produce cytokines such as IL-1ß and TNFa that stimulate the emigration of neutrophils from the capillaries so they release their destructive enzymes at the site of inflammation. The initiating cause of inflammation does not determine the results at the cellular and tissue level. In all cases of inflammation, neutrophils are attracted to the site of injury and invade the tissue, and amplify the inflammatory cascade.

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 Microlactin, a patented special milk protein concentrate (SMPC) from the milk of hyperimmunized cows. It inhibits inflammation without irritating the gastro-intestinal tract.  Duralactin is  a potent inhibitor of neutrophil adherence, migration and participation in the immune response to musculoskeletal conditions including arthritis.   Recommended for the long-term management of chronic inflammatory conditions such as stomatitis, IBD.

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This is human information but I like how it explains it: 

 How does it work?
Though the mechanism of its anti-inflammatory activities is not fully known, researchers have shown that neutrophil and lymphocytes are affected. The secondary, neutrophil-mediated phase of carrageenan-induced inflammatory response is suppressed and neutrohphil emigration is inhibited. One study done by Ormrod, et al, showed that there was an increase in the amount of neutrophil and a decrease in the number of lymphocytes in circulation. The high concentration of anti-inflammatory agents found in MicroLactin may also block the mitogenic response of lymphocytes, as well as block the response of lymphocyte to foreign histocompatibility antigens. There are a number of patents with MicroLactin, including one, the Prevention and Treatment of rheumatoid arthritis, and two, the Method of Treating Inflammation, both done by Dr. Beck and team.

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 More that 16 clinical trials have been completed which indicate that MicroLactin is approximately 60 percent more effective than glucosamine in improving joint function. A 2002 clinical study published in Current Therapeutic Research yielded results which clearly showed MicroLactin's effectiveness in relieving stiffness, immobility and pain associated with arthritis.

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The addition of hyperimmune milk protein to the diet of human patients with either OA or rheumatoid arthritis was found to considerably relieve their painful clinical signs.   In a survey of over 8,000 human patients with OA, 80.2% of respondents reported considerable improvement in joint pain with hyperimmune milk and 72.0% reported improvement in morning stiffness

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That's great that the Duralactin/Microlactin is helping Munchie so much! 

I think I might try this for Boo and his arthritis.

It may help Sebastian, too, but I'm always afraid to try something new on Sebastian (he's sensitive). When Sebastian has a pancreatitis/IBD flare, his blood work always shows elevated neutrophils, and this product claims to inhibit neutrophil production. But I can't find many testimonials for people using Duralactin/Microlactin for these conditions.

Thank you for the info cprcheetah. Great news that it is helping precious little Munchie!

Duralactin also comes in a liquid form that contains helpful omega fatty acids that the pills don't have. The paste with the lysine has the omega's, too. I am giving my kitty the liquid form using an eyedropper and I do think it helps her. I think it's a great product.