any info on pettalive c caps... thanks

m935

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Im about to purchase for cat on prednisone.... but not sure if its safe.    He may also be too far with cancer for this to help.  But wanted to try something.

  • Huang Qi (Astragalus membranaceous) is well known in traditional Chinese medicine. More recent research has highlighted the ability of this remedy to support the functioning of the immune system. Astragalus also helps to support vitality and a healthy appetite and maintain regular water metabolism. Currently, much of the pharmacological research on Astragalus is focused on its immuno-supportive polysaccharides and other active ingredients useful in supporting a healthy immune system. (Wang DC. “Influence of Astragalus membranaceus (AM) polysaccharide FB on immunologic function of human periphery blood lymphocyte”. Zhonghua Zhong Liu Za Zhi 1989;11:180-183).

  • Mistletoe (Viscum album) is used to support normal blood pressure and maintain a healthy immune system. Viscum album has been widely tested in both human and animal studies with many positive findings. In a recent study, it was determined that cellular components of the body's natural immune system (such as monocytes and granulocytes) bound Viscum album agglutinin-I molecules to a higher degree than lymphocytes, suggesting that this herb can support natural immune responses. (Hajto T, Hostanska K, Fischer J, Saller R. “Immunomodulatory effects of Viscum album agglutinin-I on natural immunity”. Department of Internal Medicine, University Hospital Zürich, Switzerland. PMID: 9179367).

  • Echinacea (Echinacea purpurea) is well known for its excellent benefits for immune functioning. Echinacea is also effective as a tonic for the lymphatic system. Regular use can help to keep your pet healthy. Over 500 scientific studies have been documented on this herb. Specific studies have investigated the immune-supportive action of Echinacea (Barrett BP, Brown RL, Locken K, et al. “Treatment of the common cold with unrefined Echinacea: a randomized, double-blind, placebo-controlled trial”. Ann Intern Med 2002; Dec 17, 137(12):939-946).

  • Ashwagandha (Withania somnifera) is one of the most important Ayurvedic tonic herbs, supporting growth, health and vigor. Regular use can help to nourish the blood and support healthy hemoglobin levels. This herb is often recommended as a strengthening and restorative tonic and has been shown to have a tonic effect on the immune system. (Davis L, Kuttan G. “Immunomodulatory activity of Withania somnifera”. J Ethnopharmacol 2000; 71:193-200.)

  • Milk Thistle (Sylibum marianus) contains a flavonoid complex called silymarin, which is largely responsible for the therapeutic benefits of this herb. Silymarin is a powerful anti-oxidant and its positive effect on maintaining healthy liver functioning would have a direct impact on the overall systemic health of your pet as the liver is one of the most important organs in the body. (Pares A, Planas R, Torres M, et al. “Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial.” J Hepatol 1998; 28(4):615-621.)(Benda L, Dittrich H, Ferenzi P, et al.”The influence of therapy with silymarin on the survival rate of patients with liver cirrhosis (author's transl)”. Wien Klin Wochenschr 1980; 92(19):678-683.) Milk Thistle is also regarded as a potent antioxidant.

  • Cat's Claw (Uncaria tormentosa) has been used by the natives of Peru for hundreds of years. Cat's Claw boasts many therapeutic benefits, among them its supportive role in maintaining immune system strength. It has been studied for its ability to support healthy cells. (Rizzi, R., Re, F., Bianchi, A., De, Feo, V, De Simone, F., Bianchi, L., and Stivala, L. A. “Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts.” J.Ethnopharmacol. 1993;38(1):63-77)

  • Rice Powder (inactive ingredient)
 

ldg

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The only one that was of any question to me was the mistletoe. This is not American mistletoe (which is toxic to cats), so I'm glad the Latin name was there. Here is a review study: http://download.springer.com/static...574_9493f2508ddf62d35c1385c438218f23&ext=.pdf

As it exhibited no immunosuppressive side effect, it can be used with the prednisone.

Another supplement to consider adding is bovine lactoferrin. It will work in concert with the PetAlive - or whatever therapy you choose to use. There are studies showing its effectiveness in fighting both lung and colorectal cancers. It provides a number of anti-cancer fighting functions, as outlined in the introduction of this study: http://cancerpreventionresearch.aacrjournals.org/content/2/11/975.full

I give this to Lazlo (cancer survivor), and to Chumley (my FIV+ kitty, due to the immunoregulatory function of bovine lactoerrin). The dose is 125mg 2x a day. I buy Jarrow Lactoferrin, I confirmed with the company that it is bovine. It comes in 250mg capsules, so the dose is 1/2 a capsule sprinkled on wet food two times a day.

While the PetAlive C caps may be difficult to get into Max (unless you can pill him) - I suspect they're bitter - the lactoferrin the cats don't seem to notice.

:rub: :vibes: :vibes: :vibes: :vibes:

:hugs:
 
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m935

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You are awesome!

Thank you for your time and advice. I purchased it last night.

I'm so nervous I won't have a chance to try it... he wasn't doing well todayw
 

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Have you asked your vet about these? Herbal medicine can be as potent as any medication (unlike homeopathic remedies). I would consult a vet both about general safety, but even more so about drug interactions with prednisone. You could try ask a vet that is experienced with Chinese medicine too, as I doubt regular vets would know much about these.
 
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ldg

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Shoot. I just wrote out an entire reply, addressing the contribution and contraindications of each component of the medication.

The bottom line? I would normally provide a similar warning. But there are two considerations here:

1) The kitty has an aggressive cancer, and the pred is being given simply to make Max comfortable. :heart2:

2) I have a holistic vet trained in Chinese Medicine and a cat that had aggressive large cell lymphoma. We opted for chemo and it worked. But We discussed supporting care, and I was familiar with all of these (and others) other than the mistletoe (Viscum album) in relation to cancer. ALL of these are contra-indicated if using chemotherapy, but in the absences of such treatment, each provides either adjunct anti-inflammatory support, activates t-cell production, provides liver support, or tonic / GI system support. Only Astralagus would be contra-indicated if the pred were being used at immune-suppressive doses - which is not the dosage of pred when being used as medication for cancer, it's provided at a dose for treating inflammation.

Some are contraindicated with other medications (ashwaganda, with sedatives, like valium or ativan, etc.).
 
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m935

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Thanks.

So I just have to ask as I don't know anyone trustworthy ...

You are saying these pills should be fine w pred?. He's taking 2 MLS twice daily.

He's so lethargic now I can't stand it. I'm going by vets later to ask about this shot he wAs given
 
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m935

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He ate wet food 3times today. Just gave him little water where he's laying and he ignored it.

Should i try dropper with water?

This am. He came up to me as I woke up like he was fine... but horrible all day since
 

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He's on pred and that's it for meds/treatment, right? Maybe the pills are worth a shot considering the alternative you're facing.

I asked about food/water because it's amazing how rotten one can feel if dehydrated. If he's not peeing or is peeing dark/stronger urine, I'd be looking at dehydration.
 
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If he is eating then things aren't serious at the moment.  I know my IBD kitty will have days where he sleeps more than usual, even be in the meatloaf position more than usual, but as long as he is still eating I don't get too concerned about it.  Have you decided about an oncologist yet?
 

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Shoot. I just wrote out an entire reply, addressing the contribution and contraindications of each component of the medication.

The bottom line? I would normally provide a similar warning. But there are two considerations here:

1) The kitty has an aggressive cancer, and the pred is being given simply to make Max comfortable. :heart2:

2) I have a holistic vet trained in Chinese Medicine and a cat that had aggressive large cell lymphoma. We opted for chemo and it worked. But We discussed supporting care, and I was familiar with all of these (and others) other than the mistletoe (Viscum album) in relation to cancer. ALL of these are contra-indicated if using chemotherapy, but in the absences of such treatment, each provides either adjunct anti-inflammatory support, activates t-cell production, provides liver support, or tonic / GI system support. Only Astralagus would be contra-indicated if the pred were being used at immune-suppressive doses - which is not the dosage of pred when being used as medication for cancer, it's provided at a dose for treating inflammation.

Some are contraindicated with other medications (ashwaganda, with sedatives, like valium or ativan, etc.).
Sorry to be totally off-topic here...

Laurie, the system should auto save a draft now. My browser closed on me and when I opened it my post wasn't there, but then I reloaded the page and it appeared. Give it a try next time. :)

M935, good luck with your cat :hugs:
 

ldg

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Thanks, good to know!

And yes - consider using a syringe with some water. You may want to learn how to give sub-q fluids at home. It's not difficult, and helps them feel SO MUCH better!

You might also want to chat with the vet about an anti-nausea medication (Cerenia), and perhaps an appetite stimulant (cypro or mirtazipine). Lazlo needed the pred, an anti-nausea med (cerenia), an appetite stimulant (we used mirtazipine - it only needs to be given every 3 days, but makes some kitties really nutty), and an antacid (famotidine, brand name pepcid a/c).
 
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m935

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I actually took him in tonight. I called and was told he shouldn't. Be this way. This vet said I could do more tests. So I have to figure out what to do with other vet being so grim. I can not spend money if there nothing to be done

I was just told right now he's OK. Thanks again denice.. I didn't get that reply until after but is helpful to know as long as heeats..

Actually I again can't thank you all enough. I know a lot of people sadly need info on this kind of stuff so thanks for your time

She did mention pepcid .. forgot to get me the dose....
 

ldg

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Best to call your vet to find out what dose she (or he) wants you to use, and how often to give it. Some are on 5mg a day, some 5mg 2x a day. Lazlo was on 10mg once a day. If pilled with it (without food), if given 1 hour before or after any food (on an empty stomach), it should provide 24 hour coverage. But.... best to call the vet.
 
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