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Stubborn herpes infection? Add Lactoferrin in addition to Lysine

post #1 of 246
Thread Starter 
In researching proactive methods of slowing down the progression of Chumley's FIV, the FIVtherapy site had quite a bit of information up on the anti-viral properties of Lactoferrin. There are a number of both in vitro and clinical studies of Bovine Lactoferrin for various things: one of them is Feline Herpes Virus.

In fact, one was published just this year. http://www.medwelljournals.com/abstract/?doi=javaa.2013.181.185

From the study:
Quote:
Viral shedding in oculo-conjunctival samples gradually decreased in almost all cats. These data suggest that the association lysine-lactoferrin could be a first choice in FHV-1 infected cats for reducing clinical signs and viral shedding.

Here's an in vitro study from 2003: http://www.ncbi.nlm.nih.gov/pubmed/12950656

I've been giving Billy various doses of L-lysine to get him to stop sneezing. We got his runny eyes under control with lysine, but he remained very sneezey.

When I found the information on Lactoferrin in regards to herpes (I didn't have the 2013 study at the time, but human study papers), I added Bovine Lactoferrin to his supplement regimen.

I didn't track how long it took to take effect. anon.gif I just noticed one day that he rarely sneezes any longer. I asked Gary if he'd heard Bill sneezing much, and upon reflection, he said "I can't remember the last time I heard him sneeze." biggrin.gif

I confirmed with Jarrow that their lactoferrin is Bovine Lactoferrin. This is important, because lactoferrin is also made from transgenically modified rice that produce human lactoferrin.

I am giving my cats 250mg daily, split into two doses, 125mg in the morning and 125mg in the evening. The Jarrow lactoferrin comes in 250mg capsules: easy to open and sprinkle on half a capsule and mix into food. I did not buy the 2013 paper to see the doses used for either lysine or lactoferrin.

It is palatable to all of my cats, some of whom are very picky (it has so many benefits, I give it to all of them now).
post #2 of 246

Bagel is my resident herpes kitten, at the age of five months old (November 2013). He's always had teary eyes, congestion that you can barely hear, and sneezing. The sneezing was the worst. Poor guy was sneezing up to ten times a day. Some days even more.

 

The L-Lysine helped with the teary eyes and the congestion to a degree. I saw more of a change when I switched to NOW Brand L-Lysine. Before I was using Lysine treats that were pulverized - they were not liked by Bagel and he often ate around it. 

 

Still, with the Lysine he was sneezing ten times+ a day. I had already upped the dosage of Lysine from 250mg x2, to 500mg x2. After talking to LDG, I too have decided to test out Jarrow's Lactoferrin. I split one capsule twice a day, along with the Lysine, mixed into ground food. Bagel has no issues eating food with both Lysine and Lactoferrin. It should also be noted that he also receives probiotics twice a day also (been on it since he was adopted).

 

It's been about a month, maybe six weeks since Bagel has been on the Lactoferrin and I definitely am pleased. Bagel has not sneezed in a few days. He will sometimes have a sneeze here and there but never more than one at a time. I am going to continue to give Bagel Lactoferrin, I may decrease the amount of Lysine to 250mg twice a day to see what happens, but I am very content with Bagel right now. He still does have the snushy congestion, which I am hoping it is due to the cold, dry, air during this season with the radiators going nuts (hoping that a humidifier will help).

post #3 of 246
I usually give my cat 500mg just at night, should I give it to him twice a day 250mg morning and night?
post #4 of 246

I believe it's because cats metabolize the doses in 12 hours. :nod: Twice a day 250mg morning and night sounds good, if 500mg daily works for him. Bagel was taking 500mg twice a day, and his sneezing was still crazy - which is why I added the Lactoferrin. 

post #5 of 246

My big guy has runny goopy eyes and Im thinking of starting him on lysine. Should I start with 250 twice a day first and see? How long usually before you would expect to notice a change?

post #6 of 246
Thread Starter 
The lysine dose I started with was 250mg AM and PM. agree.gif You should see results in a few days to a week. If not, a "flare-up" dose is often 500mg AM and PM. But it's always best to start lower and work up to it.

If that doesn't control it, Lactoferrin may help.

If it does control it, then find the lowest maintenance dose that keeps it under control once the flare-up subsides.
post #7 of 246

Molly doesn't sneeze but has the runny eyes constantly.  I've got her on lysine--her eyes are better but still not really "under control".  I'm going to try adding the lactoferrin.  Thanks so much for posting this information!  

post #8 of 246
Thread Starter 
I hope it helps! Maybe you can report back to us in about a month. smile.gif
post #9 of 246
Quote:
Originally Posted by LDG View Post

I hope it helps! Maybe you can report back to us in about a month. smile.gif

 

I definitely will !  

post #10 of 246

I got the lactoferrin today and am going to start Molly on it in the morning.  I'll let you all know how it goes.  

post #11 of 246

Wow.  The lactoferrin has definitely helped Molly.  Her poor eyes are so much better!  The only problem I have with Molly is she doesn't eat much, so she never get the full dose of lacto. or lysine.  I've recently started giving her a smaller portion of dinner with the meds in them to make sure she gets them down before getting any more food.  She LOVES treats but unfortunately I couldn't fool her by giving her lysine treats instead of Greenies or Temptations.  xeye.gif     

 

At any rate, I'm wondering if anyone knows if it's okay to just keep giving Molly the lactoferrin indefinitely?  She sure looks better and I'm sure she MUST feel better, too!  

 

Thanks again for the info, I'd never even heard of the lacto. before.  

post #12 of 246
Thread Starter 
clap.gifclap.gifclap.gif That's great, I'm so glad it helped! biggthumpup.gif

Yes, like Lysine, it's safe to use long term. agree.gif
post #13 of 246
That is awesome that it is helping. Yes you can give it long term.
post #14 of 246
I need to try this! Lysine helps a little bit, but maybe this will be better. Where do I buy this?
post #15 of 246
Thread Starter 
You can see if a local health food store carries it. You do have to confirm that it is bovine lactoferrin, not human lactoferrin.

I buy it on Amazon: http://www.amazon.com/Jarrow-Formulas-Lactoferrin-250mg-Capsules/dp/B0013OQGBY/ref=sr_1_1?ie=UTF8&qid=1386344694&sr=8-1&keywords=jarrow+lactoferrin
post #16 of 246
I got mine on Amazon too
post #17 of 246

Before I forget.

 

Bagel's snooshy sniffles have decreased tremendously with using a humidifier - they are definitely as as audible as before. I have also decreased the amount of Lysine from 500/500 to 250/250, kept the Lactoferrin the same. No changes for the worse.

 

Also, my older cat Lox had some eye boogies going on for a bit. She also went off her food, and I've been reintroducing raw/supplements to her. I haven't given her the Lysine for a week now, but have given her to Lactoferrin for four days. No eye boogies! She likes the taste of Lactoferrin better so if you have a cat like Lox who hates Lysine treats in any form and the taste of Lysine, please give Lactoferrin a try.

post #18 of 246
Thread Starter 
biggthumpup.gif That is awesome!!!!!

And yes - I think for kitties that don't like lysine, it's worth trying just lactoferrin!
post #19 of 246

That's what I've been doing recently --I've had better luck using only lactoferrin with Molly than lysine or lysine+lactoferrin. 

post #20 of 246
Thread Starter 
That's really interesting!
post #21 of 246

I may slowly decrease the amount of Lysine for Bagel as well. I definitely saw more of an improvement, a drastic one that is when I added Lactoferrin, and lowering the Lysine dosage so far has not done him bad. I'll update in a couple week again.

post #22 of 246

That's exactly what I've found, pinkman.  Molly seems to mind the lactoferrin less than the lysine.  Or maybe it's the combo she doesn't like. But it seems to be working giving her just the lacto.

post #23 of 246
I'm going to give this a try with Pushkin. He's on Lysine now 500mg twice a day, plus Interferon eye drops three times a day. There hasn't been a huge improvement with his weepy eye and I'm at the point where I really want to hammer away at this virus and try o get it under control. I don't mind if I have to give him Lysine and/or lactoferrin every day from now on, I just want his eye to stop weeping constantly.

Does anyone know if lactoferrin interacts badly with the interferron or the famcilovir pills which we're starting him on tomorrow?
post #24 of 246
Thread Starter 
It doesn't. I found the lactoferrin on the FIVtherapy site, and some FIV kitties are on interferon and lactoferrin is part of their standard protocol - and famciclovir is just an antiviral, so no, lactoferrin will not interfere. It might make them not needed if they're being used for a stubborn herpes infection. Give it a try for a few weeks, and see. I've recommended it to quite a few people at this point, and I'm getting so many reports back - this is REALLY helping, whether it's sneezing or weepy eyes. Obviously at some point, we're going to find a kitty that doesn't respond as well - and I hope that isn't Pushkin. vibes.gifvibes.gifvibes.gif
post #25 of 246

When our Thomas (Tuxedo) showed up at our door a year ago last October, he was very skinny, and we figured only about 4-5 months old, tops. We had no idea where he came from or what had happened to bring him to our door. We noticed that his eyes were perpetually teary but other than this he seemed perfectly fine. Thinking he might have been abandoned by his human or mother, I did some reading on bovine colostrum and decided to add this to thomas's food for the first month that he was with us, to boost his immunity in case he was lacking. Actually everybody got a little come to think of it. The teary eyes cleared up and these days Thomas is thriving and seems perfectly healthy. It makes total sense that colostrum and lactoferrin, given how they are derived, can be good for health conditions where the immune system might be compromised. Its great to read that these supplements can be effective in treating feline herpes of which it seems that so many cats are affected.

 

@LDG: I have read that there is lactoferrin content in colostrum but not clear whether lactoferrin is a single substance or always in combination with colostrum. From what I have read of colostrum it can be good as a lifelong supplement for optimum health.

post #26 of 246

Adding lactoferrin has really helped Molly.  She hasn't cleared the weepy eyes 100% but it's significantly better than it was on lysine only.  I'll be keeping her on the lactoferrin indefinitely.

post #27 of 246
Thread Starter 
Betsygee, that's great!

I've recommended this to a number of people on FB too. One person confused the dosage of L-lysine with the dose for lactoferrin, and her KITTEN'S weeping eyes, runny nose, and sneezing cleared up in less than a week. laughing02.gif I'm not sure I'd recommend intentionally doubling the dose.... I know that at the recommended dose there aren't toxicity issues.

But she is active in rescue, and their shelter is about to start using it for all their URI kitties. They've had so many the past year they actually have a separate section for them, and adoption programs geared specifically to them. They call them their "A-Choo" kitties. Of course, they're still very difficult to adopt out, because who wants a snotty kitten? sigh.gif I'll keep this thread updated with their results. They're looking into bulk ordering of bovine lactoferrin right now, but really want to start using it asap. (And yes, in the correct dose. wink.gif ).

Quote:
Originally Posted by oneandahalfcats View Post

When our Thomas (Tuxedo) showed up at our door a year ago last October, he was very skinny, and we figured only about 4-5 months old, tops. We had no idea where he came from or what had happened to bring him to our door. We noticed that his eyes were perpetually teary but other than this he seemed perfectly fine. Thinking he might have been abandoned by his human or mother, I did some reading on bovine colostrum and decided to add this to thomas's food for the first month that he was with us, to boost his immunity in case he was lacking. Actually everybody got a little come to think of it. The teary eyes cleared up and these days Thomas is thriving and seems perfectly healthy. It makes total sense that colostrum and lactoferrin, given how they are derived, can be good for health conditions where the immune system might be compromised. Its great to read that these supplements can be effective in treating feline herpes of which it seems that so many cats are affected.

@LDG
: I have read that there is lactoferrin content in colostrum but not clear whether lactoferrin is a single substance or always in combination with colostrum. From what I have read of colostrum it can be good as a lifelong supplement for optimum health.

Yes - the studies are in lactoferrin. But I would imagine that colostrum would have the same benefit, if not potentially more. I think part of the difference in long term use decision would be cost. But that's great, and I'm glad Thomas is doing so well! clap.gifclap.gifbiggthumpup.gif

I "found" the lactoferrin when researching how to help slow down the progression of the FIV virus in one of our kitties. But it just seems to be a very powerful immune system regulator, particularly targeting a number of different viruses.
post #28 of 246

Thanks LDG. Yes, its great that there are natural solutions such as the lactoferrin, colostrum, L-Lysine and such. I was looking at interferon at one point for Max thinking that he could benefit from this to prevent the rodent ulcers he gets, but my vet and I agreed that this is a heavier gun and more appropriate for more serious situations such as FIV and FEL-V. I think the L-Lysine I am using on Max is making a big difference .. Max's eyes seem brighter and overall he just seems more alert and active than he has been. Although, pooping more often helps, of which we have had some marvellous breakthroughs recently. :D

post #29 of 246
Thread Starter 
Oneandahalfcats, I recommended lactoferrin to someone that volunteers as a foster for a local shelter. It cleared up her kittens' sneezies so fast, she recommended it to the shelter - apparently they have so many URI kitties (and have, for some time), they have a separate ward called the "A-choo Kitties" - and they've been working to develop strategies to get the snotty kitties adopted out.

They put a few days of their own research into it, and found a supplement they'll be bulk ordering. I found it REALLY interesting that it has colostrum AND lactoferrin in it (also "Lysozyme")! It's by Allergy Research: http://www.allergyresearchgroup.com/Laktoferrin-with-Colostrum-90-Vegetarian-Caps-p-119.html

This is a LOT more expensive than the Jarrow brand (also bovine) lactoferrin I'm using. But it'll be REALLY interesting to see what happens...

When I have any news, I'll update the thread.
post #30 of 246
Quote:
Originally Posted by LDG View Post

Oneandahalfcats, I recommended lactoferrin to someone that volunteers as a foster for a local shelter. It cleared up her kittens' sneezies so fast, she recommended it to the shelter - apparently they have so many URI kitties (and have, for some time), they have a separate ward called the "A-choo Kitties" - and they've been working to develop strategies to get the snotty kitties adopted out.

They put a few days of their own research into it, and found a supplement they'll be bulk ordering. I found it REALLY interesting that it has colostrum AND lactoferrin in it (also "Lysozyme")! It's by Allergy Research: http://www.allergyresearchgroup.com/Laktoferrin-with-Colostrum-90-Vegetarian-Caps-p-119.html

This is a LOT more expensive than the Jarrow brand (also bovine) lactoferrin I'm using. But it'll be REALLY interesting to see what happens...

When I have any news, I'll update the thread.

That's awesome about the lactoferrin being used to clear up the URIs - so much better than having to put everyone on Clavamox! :)

 

The Colostrum I purchased in case you're interested is strictly the Bovine lgG (bovine immunoglobulins), brand name Immu-Start 50 by Immutek. It is a 400g bag of powder which costs about $18 which I thought was quite reasonable. It's used on young calves as a supplement to boost their immune systems but also used by holistic practitioners for other animals and humans for the same purpose from what I researched.

 

Look forward to hearing more about the lactoferrin! :) 

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