Very sick cat, any help would be fantastic.

    So, my 5 year old cat, Endora, is very sick. I noticed her starting to lose weight, but by the time I took her in she had gone from her 10lb weight, to 6lbs. She's eating and drinking water, but not as much as she used to. After bloodwork and then some, the vet has come up with the following: There is trouble with her liver, she's dehydrated, and she has jaundice. So they pumped her full of water and gave me 4 different medications to give her for the next 2 weeks. She isn't at the point where we have to force feed her, as we're pulling in various things to feed her. I guess she liked Turduckin, the wet food. I might end up force feeding her a little bit every day, just to be on the safe side. Anyways, I grabbed a copy of the bloodwork they sent me, so I'll post that too, well what's high/low anyway.

If you have any suggestions, experience, comments, what not on this whole situation... that would be fantastic.

At the moment I am absolutely stressed out and worried to no end about her. The Vet did mention that we're giving this antibiotic set 2 weeks before the next blood work. Then, if it gets better we continue the antibiotics, if it doesn't then it's off to an xray/ultrasound. I just want my baby better.

Blood Work:
ALK. Phosphate: 947 (H)
ALT: 400 (H)
AST: 174 (H)
GGT: 12 (H)
Total Bilirubin: 10.4 (H)
Direct Bilirubin: 8.3 (H)
Indirect Bilirubin: 2.1 (H)

MCV: 34 (L)
MCHC 36.7 (H)
Neutrophil: 84.9 (H)
Lymphocytes: 8.7 (L)
Monocytes: 5.1 (H)
Eosinophil: 1.3 (L)

Absolute Lymphocyte: 1061 (L)

Notes state that her SPEC fPL is a 2, which is in normal range, so that it is unlikely pancreatitis.
Also, her T4 is a 1, and is in normal range.

I can provide anything else if you need it.

What are the meds she was issued? The tremendous amount of weight loss for a cat her age is startling. The liver could be the problem or a symptom of another problem such as kidneys, etc. Did the Vet offer any information here?

In the meantime, it is critical that she eats. Not enough food intake causes the liver values to go off the chart and the cat starts metabolizing her own mass. Make sure that she is eating enough, preferable, wet food. For a cat her size, this should be about a 5.5 oz can every day. Preferably, the food should be a high quality food such as Wellness, EVO, etc. But just make sure she is eating enough.

Based on the elevated liver enzymes, and the significant weight loss my guess is that your kitty has Hepatic Lipidosis (aka Fatty Liver Disease).  You may want to google it ("feline fatty liver disease") to learn more about it.

Cats develop this when they lose weight too quickly - as your cat did.

The only real treatment is aggressive feeding of proper prescription canned food.......I believe it's generally Hill's A/D.  I'm surprised your vet didn't advise this?   In order for the liver to heal, they must receive plenty of appropriate food each day.   Most have to be syringe-fed several times a day as they feel so rotten they simply won't eat enough on their own.   Dehydration can be a problem, too.....as they'll often throw up, sometimes have diarrhea.  

There are some supplements that people give to cats with this, to help the liver heal....one is SAMe  ( http://www.peteducation.com/article.cfm?c=2+2103&aid=3062 ...another is Milk Thistle.

I'd read everything you can on Fatty Liver Disease in cats and how to treat (diet, supplements, ensuring adequate hydration which sometimes means learning how to give Subcutaneous fluids at home, meds for nausea, antibiotics....eventual use of appetite stimulants, etc).   Don't rely on your cat to eat enough on his own.......aggressive feeding (small frequent meals) of the appropriate prescription canned food is absolutely critical for survival.
 

I concur that this sounds an awful lot like Hepatic Lipidosis (HL), and I'm kind of shocked that your Vet didn't recommend that you force feed her, at least to supplement what she is eating, since you already mentioned that she isn't eating as much as she normally does.  But it IS a good sign that she is still eating.  Once full fledged HL sets in, cats usually totally refuse to eat.  Mine did.  As a matter of fact, we had to have a stomach tube installed in order to feed him every 4 hours for several months. 

Here's a recent thread about a cat with HL;  http://www.thecatsite.com/t/250863/...ment-advice-needed-diagnosed-saturday-11-3-12

that Endora recovers quickly.  Do keep us posted and remember we're here for you

So we're onto day 2 of medications (Oh god, 5 pills a day. Horrible!). Thanks for the comments, the suggestions are well taken. We're calling the vet today and asking about forced feeding/recommendations by the vet. Currently, I'm giving her water after each pill because she hasn't been drinking a lot of water. Not to say this makes for a happy kitty. On the plus side, even though it's day 2 with medications and 3 since her vet appointment, she's getting her personality back a little. And by personality I mean growling, flicking her tail, and she even attempted to play today. She's sleeping for longer than she was, which is actually good. She's very constipated, so we're also keeping an eye on that. After reading some of the comments I am wondering why the vet didn't suggest more for her than the pills... I'll talk to her today. As for kitty and the pills, oh man is she a pain. We're managing, but wow. Next time I'm asking for liquids.