How often do you supplement L-Lysine and for how long--and for what? And other questions. :)

feralvr

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But Lauren..Shouldn't these dosages be taken on a cat to cat basis?
However I hope that more vets will update themselves to know that a higher dose may be more effective.
Yes, of course, each kitties case would be different. :nod: I am doing what is recommended for Perla by her eye specialist and just passing on the information. Each owner should always do what their vet is recommending for each individual cat. I think if a lower dose works for some herpes kitties then less is more. For Perla, the lower dose does not help her eye. At least I know that a dose of 1000 mg. Divided into two doses daily is safe for Perla. :)
 
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whollycat

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I'm sure, that as with any supplement, it's best to start with the lower dose, and if kitty doesn't respond, then increase the dose. And now we know, the dose can safely be increased to 1000mg (or twice that during a flare-up) daily.
I'm with Laurie, Lauren, and Otto on this. Each kitty is an individual, so my opinion is to start with the lowest dose and if no improvement you can always increase it. I talked to my main vet, Wendy, and she says what I've always thought: start at 500mg divided between two doses per day in the acute phase, then maintenance dose of 250mg divided between two doses per day. She did say if kitty doesn't respond to 500mg, you can up the dose, etc.

It all depends on the individual kitty and how bad the virus is attacking their system. So if a lower dose is controlling FHV, then I would stick with what is working.

Still investigating as to how much arginine needs to be in the diet before adding too much lysine may cause problems. At least we know that a diet with NO arginine is way bad.
 
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flintmccullough

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Hmmm...  I have read this entire thread and done some research on my own.  Now I am more confused than ever.  Is 500mg too much as a maintenance dose?  I give my 500mg daily.  I wonder if I should reduce that to 250 and see what happens. 

 
Hey NutroMike!  


Was talking to one of my show friends in VT last night, and told her about the L-Lysine discussion, lol.  Her vet is of the mindset, that it should only be given for a specific need or medical issue, as in kitty is sick, like Feralv's kitty, or show kitties that run heavily, or mine, when she had an eye infection, etc.  Like it has a reason to be in the system, like it has something to attack or fend off, per say, not really sure how to word it, lol.  Her vet felt, if given every day, when there is no specific reason for it, it loses its effectiveness, per say, kinda like, if we took antibiotics all the time, when there was no need for it, our systems, build up an immunity, per say, and its not as effective.  Hope I explained that OK, lol.

Neither she or I, run heavily, and we only give it, when kitties are sick.  So I thought it was an interesting, another point of view, on the subject.

Are your kitties sick?  Do you show them heavily?  Why do you give it to them, everyday? What are you trying to accomplish?  Just wondering, lol, as another point of view, in this very good discussion.  
  
  
  
 

feralvr

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Hmmm...  I have read this entire thread and done some research on my own.  Now I am more confused than ever.  Is 500mg too much as a maintenance dose?  I give my 500mg daily.  I wonder if I should reduce that to 250 and see what happens.  :dk:

 
Hi Mike :D. I was wondering the same as Flint above. Do your kitties have FHV? If so, then I agree that starting at the lower dose would be just fine and see if you get an improvement. I am just forwarding my information from Perla's specialist who says that for FHV kitties - 1000 mg. divided into two daily doses is what is required - she did say that any less for Herpes kitties might not be beneficial in controlling and warding off the chronic virus. Herpes is a chronic condition for some of these poor kitties. So you just have to experiment with the dosage, i.e. starting low, and see if there is improvement in symptoms.

I would not be using Lysine if I did not have three Herpes kitties. I do not give it to Walden at all as he has never shown any signs of being off or ill. I only give it to the cats who are chronically unwell and battling the virus., like Perla. Perkins and Presley are on an as needed basis. Pipsqueak gets 500 mg. daily unless I see eye goop in the corner - then I go to 1000 mg. for a few days and then back down. But for Perla, who has this herpetic eye - she will stay on 1000 mg. daily for as long as Dr. Lindley recommends her to do so.
 

feralvr

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I found this information at vetinfo.com, By giving daily L-Lysine supplements to your cat, you increase the quantity of L-Lysine available for the cat's cells to use, which means that the cell uses more arginine for its natural functions. This leaves less arginine available for the production of the cat herpes virus, thereby slowing the growth of the infection."[/I]
This was my understanding from Dr. Lindley. That is why she is insisting that Perla stay on the 1000 mg. daily of Lysine. It creates more cells for the cat to use normally which leaves less arginine for the herpes to take over, slowing the growth. IF you stop the Lysine or drop the dosage to much then it might be ineffective against assisting the cat's body to control the virus. This made a lot of sense to me. She also reiterated to me that there is no risk to Perla getting the 1000 mg. per day in regards to depleting arginine even at 25 times that amount, and I am going to trust her on that. :cross: I feel that the risk (if you want to call it a risk, that is) giving a herpes cat Lysine as opposed to the cat possibly losing an eye down the road - outweighs it in my mind. Like Otto said somewhere in an earlier post :D, quality of life. Sometimes we have to pick the lesser of two evils - (again, if you want to call Lysine - evil at high doses :lol2:) (just adding a laugh or two.) ;)
 
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catspaw66

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This was my understanding from Dr. Lindley. That is why she is insisting that Perla stay on the 1000 mg. daily of Lysine. It creates more cells for the cat to use normally which leaves less arginine for the herpes to take over, slowing the growth. IF you stop the Lysine or drop the dosage to much then it might be ineffective against assisting the cat's body to control the virus. This made a lot of sense to me. She also reiterated to me that there is no risk to Perla getting the 1000 mg. per day in regards to depleting arginine even at 25 times that amount, and I am going to trust her on that.
I feel that the risk (if you want to call it a risk, that is) giving a herpes cat Lysine as opposed to the cat possibly losing an eye down the road - outweighs it in my mind. Like Otto said somewhere in an earlier post
, quality of life. Sometimes we have to pick the lesser of two evils - (again, if you want to call Lysine - evil at high doses
) (just adding a laugh or two.)
Yes, I agree.  I just wish I had known about lysine before Silly started having the major problem with her eye.  Maybe she wouldn't have lost it.  Julie has the virus I am sure and I hope Sheba and S&S don't get it.
 
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whollycat

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Y'all are bringing up some interesting points. Use with FHV I can understand giving it, but for other diseases that don't replicate a virus from arginine, would this cause problems? Just thinking out loud here because the reason for giving lysine (and from my travels about the internet
) I've only seen if given for FHV and other related diseases that "feed" off arginine. If given for a non-FHV sort of illness, might it NOT be a good idea? Might it upset the delicate balance of the amino acids? I'm tired, so maybe my thinking is "off" at the moment.
 

flintmccullough

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Y'all are bringing up some interesting points. Use with FHV I can understand giving it, but for other diseases that don't replicate a virus from arginine, would this cause problems? Just thinking out loud here because the reason for giving lysine (and from my travels about the internet
) I've only seen if given for FHV and other related diseases that "feed" off arginine. If given for a non-FHV sort of illness, might it NOT be a good idea? Might it upset the delicate balance of the amino acids? I'm tired, so maybe my thinking is "off" at the moment.
That is another good thought.  So I will throw this situation, into the mix, lol.  


One of her cats, has heart issues, forget now, exactly, what it is, but kinda think, its HCM. So I know, from my own experience, that HCM weakens the immune system, or rather, the kitty then has a weakened immune system.  That cat, gets L-Lysine every day, if I can remember right, she gives him 500 mgs, 250 twice a day.  

So, in following the FHV theory, would that not be a different, or a different disease, per say?  Or do I need to go to summer school, cause I didn't learn right, about the very nice post WhollyCat wrote about arginine, lol? I don't know, I am asking, lol.

I do know, when she had her eye infection, my cat, not my friend, lol, I started giving her LL, and my vet said to continue it.  How do you pronounce arginine, so I don't sound like an idiot, when I ask my vet about her thoughts, on Friday, lol.  
  
  
  


This is a great discussion, and everybody has some really good thoughts and points of view.  
 

feralvr

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OH YEAH - wanted to add to my earlier post about what Dr. L. told me. She used the word "dormant". Lysine helps keep Herpes "quiet" SO if you are past the "flare-up" stage and drop the Lysine back down to what you consider maintenance - them the virus has another chance to "waken" and then another "flare up". That is why Perla must stay right where she is with the Lysine dosage. Keeps her virus "dormant". I pray this keeps working. :cross: :vibes: Perla... :heart3:
 
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feralvr

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Yes, I agree.  I just wish I had known about lysine before Silly started having the major problem with her eye.  Maybe she wouldn't have lost it.  Julie has the virus I am sure and I hope Sheba and S&S don't get it.
:hugs: :hugs: :hugs: :hugs: For Silly :rub: :vibes::vibes::vibes::vibes: Your a great meowmy. :heart2: :hugs:
 
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whollycat

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Originally Posted by FlintMcCullough  

One of her cats, has heart issues, forget now, exactly, what it is, but kinda think, its HCM. So I know, from my own experience, that HCM weakens the immune system, or rather, the kitty then has a weakened immune system.  That cat, gets L-Lysine every day, if I can remember right, she gives him 500 mgs, 250 twice a day.  

So, in following the FHV theory, would that not be a different, or a different disease, per say?  Or do I need to go to summer school, cause I didn't learn right, about the very nice post WhollyCat wrote about arginine, lol? I don't know, I am asking, lol.
I've only seen L-Lysine used for kitties with FHV and other immune system repressive-type diseases, like skin diseases, allergies, etc. These diseases "attack" the immune system. With HCM (or CHM) one would be looking at supporting the heart and related blood issues with that, so I don't know if L-Lysine would be any help unless latently infected with FHV. Probably isn't hurting,
but there are much better supportive supplements for HCM, since their immune system isn't "repressed" or under "attack" by the actual disease, as in the other health issues used for L-Lysine. (HCM supplements would be lots of Taurine, CoQ10, L-Carnitine, fish body oils, and vitamins and minerals, to name a few.) Even in all my searches, FHV (and related) disease(s) have been the only ones that suggested the use of L-Lysine or diseases concurrent with FHV.

Just my thoughts. Anyone with kitties that have heart issues maybe could weigh in.
 

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I am just floored by how intelligent you guys are. Not just you know more than most vets I've talked to, you are also sensible and considered!

Since being completely blindsided by their early CRF assessment, I've been scrambling to find a prescription renal food that's acceptable. None are ideal, so probably will compromise something. I can't make the food so it's properly balanced nutritionally. Catinfo.com is helpful, but I'm in need of any suggestions out there.

Like WhollyCat, I fear the L-Lysine may be involved causing this in all three of my unrelated cats getting 500mg 2x/day,1000 mg/day. Recommended long-term dose: "can't overdose it". Hmm.

We stopped L-Lysine and I'm praying for no permanent damage, (likely there is) while taking care to do kidney support. Salvador has had past FHV eye, etc and other two some auto-immune problems as well. But, nowhere near as bad as Otto's kitty, luckily. I'm hoping ours will stay in check, but surely if they were as serious as Tolly had, I would be doing exactly what Otto did. L-Lysine was undoubtedly better for Tolly than the suffering without it, as there is no cure for the viral infection. As well, there is no cure for CKF so it just has to be on a cat-by-cat basis that we determine what is best. That doesn't require knowing all the science behind it. Just knowing the cat!
 

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I have been giving my cats L-lysine for years, my Vet told me that L-lysine is very good for cats. 2 of my cats are FIV+ and they had ring worm I gave them 500mg of L-lysine twice a day and the ring worm was gone in a month.

I see a big difference with my cats since they are on L-lsine.

Thanks

Toniann
 

maureen brad

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I feed 500 mg. daily. I have been doing it for 5 months. Vet told me there would be no harm if I do it forever. L-Lysine is helpfull to my cats who have FIV and stomatitis. I also have a cat with allergies and reoccurring conjunctivitis. My FIV kitty has eyes that were always so runny. The Lysine has been very helpful as has Zyrtec.
 

catspaw66

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I have been giving my cats L-lysine for years, my Vet told me that L-lysine is very good for cats. 2 of my cats are FIV+ and they had ring worm I gave them 500mg of L-lysine twice a day and the ring worm was gone in a month.

I see a big difference with my cats since they are on L-lsine.

Thanks

Toniann
 
I feed 500 mg. daily. I have been doing it for 5 months. Vet told me there would be no harm if I do it forever. L-Lysine is helpfull to my cats who have FIV and stomatitis. I also have a cat with allergies and reoccurring conjunctivitis. My FIV kitty has eyes that were always so runny. The Lysine has been very helpful as has Zyrtec.
Are you both talking about Feline Immunodeficiency Virus =FIV (Kitty AIDS) or Feline Herpes Virus = FHV?  There is a lot of difference.
 

oneandahalfcats

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Hello everyone. I am new to this forum but have visited a few times in the past.

This conversation here at CatSite came up in a recent search on L-Lysine as I am contemplating giving this to our nine year old, Max, who often develops rodent ulcers. I am also hoping that it helps to give Max a boost of vitality as I have read that this can be one of the benefits to giving L-Lysine.

I have discussed this with my vet who thinks giving L-Lysine to Max, is a very good idea. I had concerns as well naturally as to whether giving this would be appropriate. My vet suggests that 1-2 drops of Liquid Immuno, which is a brand of L-Lysine product, is sufficient but dosage ultimately goes to weight of the cat.

In response to the concerns people have expressed regarding arginine, I found the following page at NCBI (US National Library of Medicine National Institutes of Health), which seems to confirm that giving L-Lysine in small doses (in this case 400mg which is equivalent to 1/8 teaspoon) was effective in reducing viral shedding and would not interfere with arginine levels. Here is the link : http://www.ncbi.nlm.nih.gov/pubmed/12518876

If anyone is reading this and has answered here, or is currently giving L-Lysine to their cats, I would be interested in hearing about how things are going.

Thanks for reading.

Brenda
 
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