Let me just preface this by saying... I work at a vet clinic... I have pilled A LOT of cats!
But my own cat is THE WORST. He is on metronidazole right now for his recently diagnosed IBD. I think we have about 5 more days left of it, and he gets it twice a day. But I can never get the full dose into him because he's such a brat about it. Unfortunately metronidazole is a very bitter pill, so that makes the situation so complicated. As soon as the pill touches his tongue, he starts foaming at the mouth and trying to spit it out. It's hard to even get him to THAT point because he thrashes in every which way and fights me so hard when I open his mouth. Talk about a moving target.
I've tried minimal restraint. But he really needs to be well restrained for this.
I've wrapped him in a towel. Nope.
I've used a pill gun. He spit the pill right back out.
I mixed it in his wet food (after he spit the pill out and it was already crumbling and turning to powder) and he DID eat the food, but it took him an entire day to do it.... I know it ruined the taste of the food.
I dissolved it in water, sucked it up in a syringe and tried giving it that way. He immediately spit it all back out and fled the scene.
I have never had such a hard time pilling a cat before. Figures it would be my own pet that gives me such grief (guess it's better that way though, lol!).
Any other suggestions?! I feel like I've attempted it all! I'm used to medicating my dog, who eats pills like they're bacon.