Clostridium Perfingens Enterotoxin?

I may finally have an answer to my 8-month-old's chronic diarrhea. 

Lulu has never had normal poop in the 5 months she's been with us. Several vet visits with fecal smears, an ELIZA(?) test, blood tests all showed nothing. We changed her food, thinking she might be allergic to chicken, finally settling on duck based canned and dry...no change. Added fiber, pro/pre biotics all did nothing.

Last friday I took her to the vet again and he put her on Hills Z/D while ordering a fecal PCR panel. The canned Z/D, by the way, looks like plastic...it's weird. But Lulu didn't mind, she seemed to like it. However, when I called the vet yesterday to get the results from the PCR, I was told that it was positive for both Clostridium Perfingens Enterotoxin and feline coronavirus

Does anyone have experience with CPE? Lulu is now on a 10-day regimen of Baytril tabs and Flagyl tabs. I also found out online that it is pretty uncommon and that adding psyllium to the food is recommended. I asked the vet and he said about a tsp/day. Does that sound right?

I hadn't heard of the disease so did a google search on the topic. Apparently Clostridium Perfingens spores are VERY common in cats - roughly 80% of cats will test positive for them. But not all cats develop diarrhea from it, and those that do are treated with an antibiotic. Enterotoxin is just one of the forms of the spores.

Feline coronavirus is another disease where a lot of cats test positive and can occur in 2 forms - one causes intestinal issues and the other can cause FIP. Assuming that it is the intestinal form, what I've read is that there is no treatment and a cat will recover on its own.

If it were me, I'd be cautious about introducing too many new medications at one time. Get thru the antibiotics from the vet and then consider adding things like psyllium. If she doesn't start to recover right away, you don't know if the drugs aren't working, or that she is reacting adversely to the changes you have introduced. I'm curious why you chose that supplement, as it looses stools.

This is something you clearly want to stay close with your vet on until she has fully recovered.

from what I have now heard from my vet and VT and from what I've seen online CPE conditions in cats are rare compared to dogs. Makes me wonder if my dog has something too or if he even had the spores in his system and introduced them to her as soon as she got here. Hmm, I don't even know how this is spread...I guess it doesn't matter at this point, dog and other cat are healthy.

Yes, I'm definitely doing what the vet tells me. He was the one who suggested that we drop the Z/D and go back to the regular food. He thinks now that it is more likely that the diarrhea comes from the CPE. He didn't want to mask the effectiveness of the meds with the cold-turkey introduction of the new food (mainly the dry). 

Do you mean why did I chose psyllium? In the beginning, when my vet checked her out he recommended trying either that or pumpkin (I think I suggested that), saying the extra fiber works both ways - loosening and binding. I believe I've seen it recommended on the forums a lot too? But in the end it was the article on petmed.com that suggested it specifically for CPE for maintainance.