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Zeniquin...why can't you...

post #1 of 5
9/20/11 at 3:28am
Thread Starter 
give your cat anything containing Carafate (sucralfate), antacids, or foods and vitamin/mineral products containing iron, aluminum, calcium, magnesium, or zinc.

I can't find food that doesn't contain at least some of those. I found some treats that didn't and give her those, but I would really like to know why.
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post #2 of 5
9/20/11 at 4:35pm
Probably creates a reaction of some kind. You could call the regular pharmacy and ask. Are you giving your kitty zenequin?
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post #3 of 5
9/21/11 at 3:14pm
Thread Starter 
Quote:
Originally Posted by stephanietx View Post
Probably creates a reaction of some kind. You could call the regular pharmacy and ask. Are you giving your kitty zenequin?
Yes, I'm giving her zenequin. I am not giving her the food with that in it within two hours, but I'm just curious why.
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post #4 of 5
9/21/11 at 4:29pm
Calcium, magnesium, iron, sulcralfate, etc. prevent the medication from being absorbed--your kitty wouldn't have enough of the medication circulating in his/her bloodstream to be effective in killing the bacteria. Zeniquin is in the same family as human antibiotics Cipro and Levaquin, which have the same warnings about avoiding calcium, magnesium, iron, sulcralfate, etc. Giving the medication on an empty stomach avoids the interaction between those substances and Zeniquin.

http://www.drugs.com/vet/zeniquin.html
"Compounds (e.g., sucralfate, antacids, and mineral supplements) containing divalent and trivalent cations (e.g., iron, aluminum, calcium, magnesium, and zinc) can interfere with the absorption of quinolones which may result in a decrease in product bioavailability. Therefore, the concomitant oral administration of quinolones with foods, supplements, or other preparations containing these compounds should be avoided."
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post #5 of 5
9/22/11 at 3:16pm
Thread Starter 
Quote:
Originally Posted by cloud_shade View Post
Calcium, magnesium, iron, sulcralfate, etc. prevent the medication from being absorbed--your kitty wouldn't have enough of the medication circulating in his/her bloodstream to be effective in killing the bacteria. Zeniquin is in the same family as human antibiotics Cipro and Levaquin, which have the same warnings about avoiding calcium, magnesium, iron, sulcralfate, etc. Giving the medication on an empty stomach avoids the interaction between those substances and Zeniquin.

http://www.drugs.com/vet/zeniquin.html
"Compounds (e.g., sucralfate, antacids, and mineral supplements) containing divalent and trivalent cations (e.g., iron, aluminum, calcium, magnesium, and zinc) can interfere with the absorption of quinolones which may result in a decrease in product bioavailability. Therefore, the concomitant oral administration of quinolones with foods, supplements, or other preparations containing these compounds should be avoided."
Thank you! I figured it was something like that.
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