When you use frontline or advantage, you should also treat your home and even your garden and/or lawn if your cat spends time there. Check with your vet, but a combination of the frontline to treat your cat and the flea powder to treat all the areas in your home where the fleas may be living, like your cat's favorite sleeping areas, the powder dehydrates the fleas which kills them. Advantage works pretty good, it's similar to Frontline, so it should work well to. You should start treating your home and then see if there's any difference.