Convenia Injection

Hello, my 16 year old female cat was going to the litter box often for a day and a half so i took her to the vet where they assume it's a urinary/bladder issue.
They gave her Convenia injection (an antibiotic shot that lasts a couple weeks) and Buprenex injection for pain. They also recommend that i start feeding her a high-protein diet (she was on Renal LP). So the next day i slowly started adding in an indoor mature 27 food by Royal Canin.

Since that day at the vet she has been urinating normal but her #2 is super soft. After a week of that i took her back to the vet and they gave her Propectalil anti-diarrhea gel and Metronidazole tablets (antibiotic) for her stomach. I read online that Convenia can cause diarrhea.

Anyone experience this before? She's been on the Propectin/Metronidazole for 2 1/2 days and no improvement yet.

THANKS.

Any antibiotics can cause loose/soft stools. My foster cat has had two Convenia injections now, and both caused some mild stool issues.

It's not uncommon that antibiotics cause diarrhea. It knocks out all bacteria in the body including good bacteria which causes an upset stomach. It doesn't always happen but it can. It's a very good idea to give your cat probiotics while they are on antibiotics to help stabilize the stomach. The fact that you changed the diet probably didn't help either.

It normally takes a few days before you see results from metronisazole although it shouldn't take much longer. Does she has flat out diarrhea or just a soft stool? She's been getting a lot of medications lately and a new diet so it's not that strange that she has some problems. I wouldn't be too worried yet. It may just take some time to settle things. If it doesn't get better though you may want to consider trying another diet as that could be the culprit.

I can't believe that they are just assuming that and not testing for anything, especially if She is on a renal food as She has kidney issues, you have to be careful about giving it with kidney issues. When did She last have blood tests?

Why on earth would they recommend a high protein food if she has/had kidney issues?

She was on C/D diet for a couple years from one vet. Then my new vet said she should be on high protein so i slowly switched to Orijen. After about 4 months i took my cat back to the vet and her the levels that show kidney problems was high so they put her on Renal LP. 6 months later her blood tests were normal again but calcium high. So now after a year on Renal LP the vet says since her numbers are normal she should be back on high protein. So i started to slowly add Royal Canin Indoor Mature 27 because it said it was easier on teeth. My cat has been on dry food she ignores wet though i still wish she would switch to wet.

Anyway since a week ago when she got the convenia and pain shot the very next day the super super soft stool started. I did start to switch the cat food as well but add it very slowly. It has now been 2 days of the anti-diarrhea gel and antibiotic pill. Still soft stool. Hope it's just a side effect of the convenia shot and nothing serious.

My girl is 16. Aside from high calcium and this straining at the litter box for a day and half she's been fine. Next day after Convenia shot she's peeing normal again but soft stool. She did have asthma but since she lost weight over the past year she hasn't had any symptoms of that. I just want her to live as long and healthy as she can and hope i'm doing right by her.

I think you need a new vet, if the kidney problems She had was an insufficieny rather than an infection then the diet change needs to be for life, and even if it was an infection, at that age you wouldn't want too high a protein as their organs don't work as well. Did the vet even do a test this time, kidney issues should be monitored at least every 6 months.

I get full blood test every 6 months.

I'm so confused on whether to feed high protein or low protein..

Update: tomorrow will be 2 weeks of soft stool. She has been on the antidiarrea gel called Propectalin and also an antibiotic for stomach called metronidazlole since Monday evening (about 3 days now). She just went to the bathroom and still has soft stool. I noticed a hairball in the stool this time.

What could be causing this??? The convenia injection (antibiotic given for suspected uti almost 2 weeks ago).

I hope this is nothing serious.

Have they done a fecal? Not just a fecal floatation but the more extended version that I can't remember the name of.

I wouldn't think that the Convenia shot would cause diarrhea for two weeks. It can take a little longer for the metronidazole to start working so don't throw in the towel yet. I'd still call the vet and ask tomorrow.
Just so you know metronidazole can also cause diarrhea and your kitty has two antibiotics in her system. This may just clear up once she no longer takes any antibiotics.

It could be a number of things that cause diarrhea though and it can be very difficult to find the cause and treat it. Could you try switching back to the old food for a while to see if that helps? After all she did to well on that, right? I'd also add some probiotics to her diet to help the diarrhea.

I hope it's nothing serious but I wouldn't be too worried yet. She still has the convenia in her system and she's eating a new food plus taking another antibiotic. In my experience cats seem to get diarrhea quite easily and for the most part it's nothing serious and goes away on its own.

Originally Posted by booktigger

I think you need a new vet, if the kidney problems She had was an insufficieny rather than an infection then the diet change needs to be for life, and even if it was an infection, at that age you wouldn't want too high a protein as their organs don't work as well. Did the vet even do a test this time, kidney issues should be monitored at least every 6 months.

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not only that, but convenia for UTI? Convenia is not a good antibiotic for UTIs... not at all... Convenia is good for Skin infections, abscesses and oran infections - very good for stomatitis too. But for UTI is a huge stretch, and deemed ineffective as far as I know.
As far as antibiotics causing diarrhea for over two weeks - yep, it can happen depending on the kitty's system - my cat Bugsy is a testimony to that; he has been dealing with it for almost 8 months - yep months. It all started with a course of clavamox he took for an UTI. It put his digestive system off balance by killing the good bacteria on the tract and causing an extreme overgrowth of bad bacteria. Only now he is getting over it. Thanks to a mix of veterinary probiotic, human probiotic, and a homeopathic diarrhea medicine. All approved by my vet, of course.
As far as diarrhea gels - I HIGHLY recommend one called Diagel. It was recommended here at TCS, (also discussed with my vet). It is a single dose at must case. It is expensive - $12/dose, but AMAZING. You can give her 2 doses - 12 hours apart, and follow with a good probiotic. I bet you she will get better.

You can get Diagel on revivalanimal.com for $11.99. I haven't tried it so far but I've heard a lot of good stuff about it.

Thanks for the info! The Convenia should be wearing off by Monday. Just finished the metronidazole pills Friday and almost done with the tube of Propectalin gel. She still has not really diarrhea but really soft stool that is like a blob with no form.

I give her fish oil and probiotics too. Her normal food was still in the new mix as i was slowly fazing it out. But the soft stool started immediately the day after the Convenia injection and pain med shot Buprenex though i did start adding new food that day too. Who knows if it was the food. I've changed her food before slowly and there was no problem. Hmmm... I am slowly adding more of the old food and seeing if that helps. I've never had this problem before so 2 weeks seems like a lot to me but to know you've had the problem for 8 months makes it seems like a shorter time.

Hey there, I came across this thread and Im having the same issue with my cat. Did yours ever get over it? Mine had her Convenia shot over 2 weeks ago for a bladder infection.

Hi, sorry for delay, just noticed. Yes, my cat got better with gastrointestinal food (Prescription Diet I/d) for a month then back to regular food. No issue since.

My cat just received the Convenia injection today...I took him to the vet b/c he was peeing blood.  I was able to collect about 1ML of urine/blood yesterday right after he peed in the dog's crate (take that dog).  My cat does NOT do well at the vet - he turns into a completely different animal and actually bit the vet-tech through the heavy leather gloves with the staples on them.  The vet said that there was a lot of blood in the urine and some white cells, but he wanted to send the sample to the lab for more tests.  He said he wanted to put kitty on an antibiotic just in case it was a UTI.  I asked him if there was a medication he could inject since kitty is not nice when it comes to doing something he doesn't want to do.  I was nervous about giving him a pill or liquid meds.  The vet said there was an antibiotic he could give kitty...

When I got home, I looked up the medicine just to see what potential side effects could be and now I am completely freaking out and concerned for kitty's health (and life at this point).  I have come across more stories of bad effects from Convenia than good and am very worried.

Have you noticed any residual effects from the Convenia?

Thanks!

kw1949 said:

My cat just received the Convenia injection today...I took him to the vet b/c he was peeing blood.  I was able to collect about 1ML of urine/blood yesterday right after he peed in the dog's crate (take that dog).  My cat does NOT do well at the vet - he turns into a completely different animal and actually bit the vet-tech through the heavy leather gloves with the staples on them.  The vet said that there was a lot of blood in the urine and some white cells, but he wanted to send the sample to the lab for more tests.  He said he wanted to put kitty on an antibiotic just in case it was a UTI.  I asked him if there was a medication he could inject since kitty is not nice when it comes to doing something he doesn't want to do.  I was nervous about giving him a pill or liquid meds.  The vet said there was an antibiotic he could give kitty...

When I got home, I looked up the medicine just to see what potential side effects could be and now I am completely freaking out and concerned for kitty's health (and life at this point).  I have come across more stories of bad effects from Convenia than good and am very worried.

Have you noticed any residual effects from the Convenia?

Thanks!

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The thread you are replying to is two years old, so you may not get many answers.  But the thing with Convenia is, some cats have adverse reactions to it, and some don't.  It's the same with any drug, really.  The problem with it is that it stays in their system for a couple of months rather than a few days, so if there IS a problem, it's more difficult to deal with it. 

If it's any consolation, our girl had an abscess just last October, and we had them give her the Convenia shot as she is also very difficult to give  pills or liquid medicine too.  So we opted to give her something vs nothing for the infection. Sometimes you just have to make a choice.  Luckily, she didn't have any adverse reaction and did great on it.  Would we do it again...absolutely! 

So...try not to worry about it.  What's done is done, and hopefully your little one will be just fine