Quote:
Originally Posted by motif 
well, looking that way most of prescription drugs are toxic and actually a poisonous. Unfortunately it's true though. I have returned that collar to the shop.
p.s.
BTW I stay away from vets same way as I stay away from doctors...
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Of course, when misused many are. The difference is, lets say, between a antibiotic and imidacloprid (which is in Advantage) is that the former is still not a pesticide. Sure, taken in the wrong dose or if one is allergic it can cause serious harm, but it's actually treating a medical issues. Pesticides just kill insects.

Some classes of them are safer than others at recommended doses for use in companion animals. These are the ones you get from your vet, though Advantage is now OTC and provided that your cat is healthy (has had a vet check in the last 12 months) it should be safe to use. If you decide to go this route, please weigh your cat, know his weight, and call Bayer to verify that the box you pick up isn't a fake. That's what the Bayer customer support is for, make an employee do a bit of work.

The pesticides that other OTC products like Hartz use are often dog "safe" (and that's questionable), but their attempts at just using a smaller amount to treat a cat is a terrible mistake. Cats do not have same capacity to filter toxins through their livers like dogs and other animals do (lack specific enzymes for it to be a little more technical).
Permethrin, pyrethrins, and pyrethroids get used in these, and that's where the problem arises. You just can't dose down a chemical that's toxic to cats.
(Of some interest is that the EPA has/is studying whether/how harmful these products are to the humans that come in contact to their pets that they've been applied to. Who knows where this investigation is now with budget cuts...)
Cats do need vet check ups, just like you do need a doctor check up now and then. It's better to catch diseases early rather than wait until they're serious. Stress and possible grief aside, preventative care is often cheaper.