Stray torti is an escape artist!

So I posted maybe a couple weeks ago about two strays my husband and I found living outside our home. We brought them into our guest room and have kept them locked in there with food and water and go up a few times a day to play with them.
We usually open the windows during the day and let them get some air and close them at night bc its cold. It has gotten warm recently so we opened the window last night about 6 inches. We checked on them before bed and this morning I wasn't able to get up there until about 11am...when I got into the room I couldn't find her. It is not a big room!! I went to open the window higher for some more air and noticed the screen looked weird....the bottom corner of the screen was broken open! This room is on the 2nd floor of our house and a straight drop down. And torti is now missing. I have searched all over...I can't find her anywhere. I am worried she is hurt...I can't imagine her not hurting herself from 2 stories up?? I checked all her old outside hiding places and she is nowhere! she never even seemed interested in the windows before.
And now I am freaking out!! We sleep with our bedroom windows open every single night...what if one of my resident kitties ends up pushing on a screen enough overnight to open it and gets out?? My 3 youngest cats LOVE windows and sit in them all the time...Has anyone had a cat break a screen?? Are there any precautions I can take so it doesn't happen to other screens? I am not worried at all about the screens. I am worried about my cats!

We have gone out looking for her and have continued to put food on our doorstep, which is a daily ritual, and how we caught her the first time.
I think her getting loose is my fault. I feel awful. The two cats had been locked up in the guest room almost two weeks. There was dry food crunched into the carpet....cat hair everywhere. The room needed vacuumed bad. I could have waited for hubby to come home but I didn't. I had been having a rough day, the daycare kids were throwing huge tantrums and it was just crazy...my resident cats were going crazy, I was just stressed and wan ted to get it over with. So instead of waiting for him to get cats out of our bedroom (where they hide under the bed) and put the strays in there, I just vacuumed with the two cats in the room. The were hiding under the futon, with a sheet hanging down to the floor because they like to have hiding space...and at one point I got too close to it and torti jumped out onto the desk on the other side of the room and then ran under the desk and hid until I stopped vacuuming, got pulled her out and held her for awhile.
At some point that night/early yesterday morning she left. I think I scared her so bad with the vacuum that she felt she was in danger and had to get out. I am so mad at myself for it and so worried about her.
Still have not seen her. I guess the good thing is that the injured black kitty didn't try to get out even though he must have had time to try...
Thanks for the vibes. I was so close to having a home for torti too and I had to write them and say she is currently missing.