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10 month kitten had fever, not really eating or drinking...thoughts?

post #1 of 65
Thread Starter 
Quick background -
We have 2 rescue kittens, about 10 months old, which ended up having Feline Leukemia. They've been very strong so far (maine coon style/mix).

About 5 days ago, the male was acting odd, slow, sleeping, not eating. The next day we took him to the vet. He had a fever of about 104. He got an injection with fluids and we went back home with antibiotics.

He threw up the antibiotics, and we got a second kind. He threw that up too.

The next day he still had fever and we went back to vet where he stayed until Saturday. Over the 3 days at vet, he was observed, had blood work done and an xray.

Bloodwork was clean - white blood cells were normal, not high or low. Xray was also clean, showing no blockage, etc. He had a catheter and IV and another injection of fluids.

Vet was a bit baffled and said perhaps it was just a kitten version of the flu and we needed to wait it out.

This all started Tuesday, and by Saturday afternoon, his fever broke, was back to 101 and he was meowy and eyes bright. We brought him home.

That was about 24 hours ago. Since then, he has spurts of walking around and jumping on tables, but overall, still no real change. He has had only a little water and a small amount of food.

We've tried at least 20 different kinds of wet and dry food, gravy, treats, etc... he's just not interested in eating or really drinking.

Obviously just super worried and really want to get some food in him. Any thoughts or advice is greatly appreciated.

Thanks
post #2 of 65
Well, I don't have any experience with this. We have a kitty we have to keep an eye on because he's got an autoimmune disease that causes anemia, but we've never had a kitty (knock wood) go off their food for any unidentified reason.

I'm sorry your vet didn't think to give you something for the nausea, to help prevent kitty from throwing up the antibiotics when you had to go back to get something he might tolerate. I'm also sorry it didn't occur to your vet to give your cat Convenia (an antibiotic injection that doesn't need to be repeated).

It is important your kitty eat. Here is a thread that you may find really helpful, showing you how to force feed him for now. Syringe feeding Lucky video/If your cat is not eating

Is he hydrated? (Does his skin snap right back if you pinch it up and let go? Or does it kind of "tent?")

He wasn't blocked up in the sinuses? No runny nose or coughing/sneezing? No goopy or runny eyes?

If he doesn't improve and you find you still need to force feed him, you may want to talk to your vet about the shot of antibiotics, anti-nausea meds, or you may want to consider getting another vet opinion. Quite frankly, a second vet opinion literally saved the lives of two of our cats.

for your male! (What's his name?)
post #3 of 65
Thread Starter 
Thanks for the advice.
He is definitely hydrated. His skin snaps back pretty good, doesn't tent up. He was on IV as well as the fluid shots so that's good.

No runny nose, no weepy eyes, and no fever that we can tell (based on the the lips to the ear test - same cool temp as our other kitty).

Mainly, just moving slow, not really eating or drinking. Perhaps it's a wait it out thing? This is only his 2nd day without the fever....

Back to the vet tomorrow and possibly a second opinion if there isn't a good answer tomorrow....
Thanks
post #4 of 65
Well, when it comes to eating, you definitely don't want him to go more than 48 hours. But yes, see how he's feeling tomorrow. If he's still not eating, I'd call the vet to ask if they think it's important to get some antibiotics in him, and how they think you should manage his not eating.

post #5 of 65
I am so sorry your kitten is sick! And I couldn't agree more with LDG on this. You must start syringe feeding you cat. Did the vet offer some A/D? It is a prescription diet from Hill's packed with nutrients and is an appetite stimulant wet food. It can be mashed down for syringe feeding and this will make your kitty start to feel better fast. Cats should never go long without eating and syringe feeding then is the only option. A few small frequent amounts will help so much. Bless you for taking on these sick rescue kitties. Let us know how he is doing.
post #6 of 65
Thread Starter 
Thanks for the help everyone. Update on Logan -
back to the vet this morning. His temp is 103.3, which is said was a good thing in that his temp for the past several days had been 104.1. He said it was good because he as 36 hours with fluids or "vet care" at home, and his temp was only up to 103.3.

He got an injection of fluids today, injection of antibiotics to prevent secondary bacteria infection, and an appetite stimulant.

He is staying at the vet all day for observation and monitoring. If he doesn't eat, he will get liquid food from the vet and we'll go from there.

He thinks this is just a version of kitty flu, and because of his young age (10 months) and the FELV, he just needs more time to fight it off (as in his immune system is just not fully developed yet).

We'll see and I'll keep you updated, and also just in case in the future someone searches the forums for these symptoms, this will come up and maybe help.

Thanks again!
post #7 of 65
He's so lucky to be in such wonderful care. Do keep us updated!

More for your baby!
post #8 of 65
Thread Starter 
New upadate -
So by this afternoon, after a day at the vet, here's the update.
Logan had a temp of 103.3, by the afternoon he was down to 102.6, which is great.

During the day, the vet did:
1. Injection of fluids
2. Injection of antibiotics which will last 2 weeks; because the liquid ABs we were giving him was causing nausea (I think because of his empty stomach).
3. Force fed him Hills Prescription Diet A/D. (A mix of water and the wet food into a very soupy mix).

By tonight, for the first time since last Tuesday (today is Monday), he started showing signs of being himself. Although still sleeping, he finally started playing in boxes, and playing around with his feather toy - it was just obvious, we were finally seeing his personality back. Really happy about that.

I think a big part of it was the force feeding. They force fed him 3 times today and we did once tonight. He's on a 10 ML / 4 times per day regimen.

We will continue the 4 times a day until he starts eating on his own.

As mentioned before, for anyone running into this, like people, it just seems so important for anyone or any animal to have food for strength.

Thanks again for all the advice everyone!
post #9 of 65
Sounds like Logan couldn't be in better hands. I think he is on his way to recovering and so happy for him and you too for continued good progress.
post #10 of 65
Thread Starter 
Logan update:
Logan's still not eating on his own. Went back to vet. He has lost an additional 0.2 lbs, and his temp was back, and higher than before. 105.3 (It was a max of 104.5 earlier in the week).
Short story of it - vet said about all that is left to try is baby aspirin. He said you can give a cat 1/2 a baby aspirin every 2 days max.

So, he was given the aspirin and more fluids. He said aside from this, there is not much more to do other than wait.

Really sucks.
post #11 of 65
I am very sad to see your post. I am so sorry Logan is not doing well. This must be very difficult on you too. Sending mega and mega to you and Logan. Please keep updating. Prayers are coming your way. FeLK is a terrible disease, I am sorry.:he art3:
post #12 of 65
Thread Starter 
Thanks so much. It is tough because he's really such a great kitty
post #13 of 65
AW hun, my heart is aching for you. Very painful part of loving and having cats when they get very sick. .
post #14 of 65
Yeah, waiting is soooooo difficult.

And heaps of for your baby boy!
post #15 of 65
Thread Starter 
Logan Update:

So on Saturday we got a new update. Vet did another round of blood work. His White blood cell was up and his Red blood cell was down. He is pretty sure he has mycoplasma.

Mycoplasma is some wacked out bacteria which is transmitted via flea or tick (or from mother of kitten) and attaches itself to the red blood cells. The deal is that this is very hard to detect and often goes unnoticed on a blood test. Apparently only recently did researches find a test for it. You can read more about it here:

http://www.felipedia.org/~felipedi/w...Mycoplasma_spp

and here

http://www.marvistavet.com/html/body...us_anemia.html

So since he only an indoor kitty, we're not sure how he got this. We are actually waiting on test confirmation later today, but, in the mean time, treatment has started with 2 forms of antibiotics.

Overall, I think - think - he is starting to feel better. Yesterday he was much more "alive" than he's been. He was very affectionate and walking around (relative to the past 10 days) and even spent some time at night sleeping on our bed. That's a big sign, I feel, considering his unusual behavior of sleeping in the closet the past 10 days. This morning, though, he's back under the bed, so hard to say I guess.

For those researching their own issues of Fever of Unknown origin, and it's been more than 5 days or so, I would highly recommend a retest of blood and a test for this mycoplasma. They say it's an outdoor kitty problem, but, indoor kitties can get it.

Thanks for all the well wishes everyone, and I'll continue to update.
post #16 of 65
I hope the antibiotics do the trick! Our Tuxie fought anemia of unknown origin for years (still is). He responded to doxycycline, but also needed steroids to suppress his immune system response (of attacking his red blood cells) (that's the really short version LOL). Prednisone stopped working, but the long-acting shot, depomedrol is working. He went from needing it every two weeks to needing a shot about once a year (his fight with anemia has been going on since 2004).

for Logan!
post #17 of 65
Thread Starter 
Thanks LDG! So glad Tuxie is doing so well! This is great info and I'll keep it handy over the next couple of weeks in case I need to ask about it for Logan.
Thanks!
post #18 of 65
I hope you won't need to. !!!!
post #19 of 65
I sure hope the meds help Logan. continuing your way.....
post #20 of 65
Thread Starter 
Logan update:

The mystery continues. Logan was negative for mycoplasma.

His fever continues at 104.1, red blood cells have gone down a little bit more. At the start of this 2 weeks ago it was 36. Then it dropped to 18.5 and now is at 16. Although this new drop sounds bad, it is encouraging that the rate of drop has slowed.

Vet discussed with another vet who confirmed everything we have done so far is on course with what they would have done. They are both baffled as to what this could be.

Next course of action: In addition to regular injection of fluids and continuation of general ABs, is an injection of steroid called prednisone. This is supposed to do 3 things:
1. Reduce fever
2. Induce and increase appetite
3. Stop the white blood cells from attacking the red blood cells.
4. Reduce stress because of 1-3

Also, a consult with an internal specialist is scheduled as well.

If this does not work, the next step is feeding tube combined with a blood transfusion.

I feel like this is an episode of kitty "House"

He has basically ruled out FIP. Apparently there are 3 tell tale signs of FIP, and Logan has none of them.

On a slightly positive note, we finally observed Logan drinking a good amount of water on his own....
post #21 of 65
This sounds like our Tuxie.

The one thing I would say is that if the prednisone doesn't work, they have to consider trying Depomedrol. They are both steroids, but they DO have a slightly different mechanism of action. Tuxie never had a prednisone injection, but we gave it to him orally. Now maybe that makes a difference. And it worked at first, and his RBC went up. But then he stopped responding to it. Our vet consulted with feline blood specialists, and decided to try the Depo, which is the standard of care when dealing with Feline Hemolytic Anemia. Now - that wasn't Tuxedo's diagnosis, but he was a medical mystery (still is). But the treatment for the FHA worked.

I don't know how much you've learned about anemia yet, would you like some quick basics?
post #22 of 65
Thread Starter 
That's really interesting - yes I don't know about anemia - always welcome good real world info!Thanks!
post #23 of 65
I hope non of this scares you, but with anemia they can't figure out, it's best to be armed with information.

Basically, anemia falls into two categories: Regenerative and Non-regenerative.

Regenerative anemia means that the bone marrow works, and the body is producing red blood cells.

Non-regenerative anemia means the bone marrow isn't working, and this basically isn't really treatable.

So that's the first thing - is he producing red blood cells? In blood work I believe different measures of the reticulocytes are how they determine this, but Tuxie had to have a bone marrow aspirate to determine if his anemia was regenerative or non-regenerative. (A surgical procedure where they remove some bone marrow, usually from the hip). His problem was that he wasn't producing red blood cells (at the time), so they needed to know if he could.

It was determined he could. With your Logan, it may well be that he is, so they should be able to tell from blood work alone that it's regenerative anemia, and I'm assuming this is the case.

To "jump start" Tuxie's bone marrow, they gave him the same treatment they give people undergoing kidney dialysis: injections of Epogen (erythropoetin). So know that this is an option if it comes to that.

Anemia is determined by the Packed Cell Volume (PCV) or Hematocrit (HCT). These are basically the same measurement - the hematocrit is done with a few drops of blood in a centrifuge, and the PCV is a count of the red blood cells in a 1 ml sample of blood. But they both represent the percentage of red cell volume in the blood.

For cats, GENERALLY "normal" is 30-40.
24 and below is techincally anemic.

High teens is survivable indefinitely if kitty rests (which kitty will naturally do at those levels as they'll be low energy). But do not encourage activity.

Mid-low teens is dangerous and life-threatening, though not immediately.

When Tuxie was at 7, they gave him a few days to live.

The bottom line is at this point it seems they're looking at an autoimmune problem of unspecified nature.

The treatment with the steroids (which is what has stabilized Tuxie long term) is to suppress the immune system response (supress whatever is causing his body to think his red blood cells are like a virus).

Some things you should know when discussing options with the vet if it comes to it.

IF it comes to the point that they recommend a blood transfusion, this is something that needs to be carefully considered. Cats have far more complicated blood than humans, and if I remember correctly, to have a really good blood type matching, there's something like 24 different things that need to match. (I don't remember, but it was totally different than in people). Obviously they don't match all of them... but what this means is that cats are more at risk for not being able to tolerate multiple drug transfusions than people can.

I've read about cats here that had multiple transfusions with no problem. But our vet told us up front that there was the risk that Tuxie might be able to tolerate just one transfusion, so it should be a treatment of last choice.

We're glad we waited until they saw no other option, because he was able to tolerate just one transfusion. What happens, sometimes, in future transfusions, is that their body then sees the incoming blood like it's an invader, and the white blood cells go at it. So when they mix the bood before transfusing it into the cat, it coagulates - so no transfusion possible. If you do get to the point that you're discussing a transfusion, please ask your vet about this.

The point of a transfusion is basically to increase the amount of time to allow other treatments to work.

It sounds like your Logan is in good hands with your vet.

the pred works!
post #24 of 65
Thread Starter 
Wow thanks so much for all this information. It is REALLY helpful. At least now I feel like I have an understanding of what's going on, even if we don't know what is causing it. I'll be rereading this again for sure. Thank you so much!
post #25 of 65
!!!!!!! Please keep us posted.

When are you taking him back for his next hematocrit?
post #26 of 65
Thread Starter 
I'm not sure yet. This morning at about 11:30am, he got the steroid shot. They called at 1:30pm to say that his temp has dropped from 104.1 to 102.1 in the 3 hours since the shot. I believe they intend to do another blood test for RBC before I take him home tonight at 5:30pm...
post #27 of 65
OH! One more thing. I don't know what Logan looks like, but is his nose pink or are his paw pads pink? You can also tell by looking at his gums. But take a look at them now - you'll see they look very pale. When he's not anemic ( ), they'll be pink, and probably bright pink.

Now - when they're napping or resting, they have some kind of vasoconstriction thing going on that makes them look pale even when they're not anemic, so the best time to look at this stuff is when they've been up and doing something - like using the litter box or eating.

And the pred SHOULD increase his appetite. It definitely helped Tuxie. Tux was so anemic he'd look at his food and wonder what he was doing there.

At first, we took Tux weekly, though there may have been a little while when he was there every few days. For his epogen shots, we were there every other day for quite a while. In fact, he had other complications going on in the beginning, and we took him every day for about a month as he also needed nupogen shots (to boost his white blood cell count). But for the hematocrit, as things improved, we went biweekly, then monthly. He needed the depo shots every two weeks at first, then every month, then every few months. Now he needs them about once a year. We take him every six months just to be sure - but we keep an eye on his activity level and his "pink."
post #28 of 65
Quote:
Originally Posted by LoganPenelope View Post
I'm not sure yet. This morning at about 11:30am, he got the steroid shot. They called at 1:30pm to say that his temp has dropped from 104.1 to 102.1 in the 3 hours since the shot. I believe they intend to do another blood test for RBC before I take him home tonight at 5:30pm...
I'm sorry, I forgot he was staying there.

I don't know if it'll work that quickly... be great if it would!
post #29 of 65
Thread Starter 
Wow that last bit of info about the pink was also great. What was the world like 10 years ago or so before forums? lol - I mean, it's really amazing that you can make a post about a mystery illness in a cat, and moments later, someone is giving you tons of world information!
post #30 of 65
We wouldn't even HAVE cats if it weren't for TCS!

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