Help! Family Pet very Ill.

One of our family cats has fallen very ill. Some backstory: About a year ago her left eye went dark. I dont know if this has anything to do with it but i figured id mention it anyways. I don't know if she's blind in it or what but its darker than her other. 6 months ago she got a supposed inner ear infection, was stumbling around, we put her on anti-biotics and she got over it.

Ever since then however she's lost weight, she used to be a fat happy cat, not obese, just a big ole teddy bear. Within the last 2 months shes gone down hill alot, she was throwing up almost EVERY day and not drinking water, and when she did drink water she threw it up. She's lost over 1/3d of her body mass in the past 6 months(ish). We've taken her to the vet 3 times in the past 2 weeks and they found nothing on her blood test abnormal and nothing on her x-rays except a few things.

Those things were her liver enzymes were elevated SLIGHTLY, the vet said it was nothing to worry about because it wasn't elevated enough to be anything. And on her X-rays her intestines appeared "thickened". The vet suggested Inflammatory Bowel Disease or colon cancer. We got prednizone and leukeran chemo pills, as well as some new food and a pill to help her stomach. (She had a sub-q on 2 of the 3 visits to the vet)

The first day back everything seemed great, she was eating her food like a starving dog and didnt throw any up, she was perky and walking around like she used to. Today has been horrible, she's been sleeping for around 15 hours straight, ate very little and she looks dreadful. She's a little shaky, I think she has a bit of a fever and shes very lethargic.

We've only been giving her the prednizone because she wont take the stomach pill (its huge) and we don't want to give her the chemo pill because there are some scary side effects that I think right now would make her worse.

UPDATE: This morning she was looking just as bad, she wouldn't eat (other than some kitty treats) and wouldn't take her meds. We managed to give her the pill for her stomach with some butter. We gave her 100 milliliters of SubQ and after that she drank water for a few minutes and she hasn't thrown up her water which is good. I think the reason she won't eat is because we've been hiding her meds in her food and shes pretty smart so I think she knows that.

We called the vet and the vet wasn't available to talk on the phone. We'd like to get a second opinion but we don't want to spend another 300 dollars on another set of blood tests and x-rays.

Is it possible the prednizone is too harsh on her? We gave her 10mg 2 days in a row per vets orders. She hasnt got it today yet though.

FYI: She just turned 10 so she's not that old.

What a long day, ok...

UPDATE: Me and my mom had a gut feeling she wasn't well and I didn't want her to just sit there in pain so we rushed to another vet for a second opinion. He did a full physical exam, a very nice person. He told us that she shouldn't be taking any medicine orally because she's difficult and its stressful. He told us on the X-rays her bowels didnt look anything out of the norm to him, he prescribed prednisone in a thermal gel that we just rub onto her ears as the ONLY medication to give her and a specialized dry diet. We got everything and when she got home she ate a bowel of her new food, had a bowel movement drank some water and now she's sleeping in her favourite spot acting like her normal old (skinnier and weaker obviously) self.

Thanks to everyone for the support, I'll update this thread if anything new happens.

UPDATE: Our kitty is doing slightly better but still not that great. She still has a fever and sleeps 90% of the day, she drinks water but she eats very little and we can't seem to coax her to eat more than a few bites of her food and maybe a cat treat or 2 if we are lucky. We've been giving her prednisone via a transdermal gel, we gave the vet a stool sample and are hoping for the results soon because she doesn't look good and her 3d eyelid started showing today when her eyes are open and I know that means she's feeling pretty bad.

We gave her a SubQ this morning to maybe help with her fever a little, she perked up slightly. She's been sleeping on my bed for 7 hours now. The vet suspects maybe colitis or some type of ulcer. Hopefully the results come back and it's an easily fixable issue because she doesn't seem to be responding to the prednisone. On a high note she hasn't thrown up in a good while.

She also still purrs when I pet her and will mew at me when I come into the room if she's awake.

Ok, if we still can't get her to eat tonight when she wakes up I will do this. Thank you.

Ok you are right. She hasnt ate a whole lot the past 2 days and now today. I will do what I can.

We found a technique to feeding her, she really likes to be clean so if we put a little food on her paw she licks it off and wants more. She's ate probably about a 1/5th of a can of food, but progress is progress right?

Yeah that's what we are using, except it's Hills A/D critical care or something like that. We also have dryfood by the same company. She isn't too interested in it. It was about 1/5th of a normal sized can. Ill get her to eat some more tonight.

Is it possible she has fatty liver disease? It's something I've always had in the back of my mind. I haven't noticed any jaundice but other than that she fits almost all the symptoms. The vet said her liver enzymes weren't elevated enough to be worried about but that was on bloodwork from almost 2 weeks ago when she was still somewhat healthy, it could've progressed ALOT by then, right?

Right now she looks dreadful, with her eyes open her 3d eyelid covers half her eye, you can feel her entire spine and backbone and she's been sleeping on my bed for close to 12 hours and hasn't gotten up to do anything. I don't know how much longer she will last.

What do I do?!?!

I managed to feed her around another 1/3d of the can bit by bit. Took about an hour but at the end she got close to half the can. I will use this technique and feed her as much as I can a day.

She seems like she wouldn't eat unless it was a tiny small bite size I put in front of her, after that she laid on my computer chair for a while and then walked out and drank alot of water which is suprising because she got 200 mL of SubQ fluid this morning, she was acting like she was going to maybe vomit because her stomach was making some odd movements but she hasn't yet.

She was acting strange though, she went to the bathroom and then stood near the catbox and was looking really really frail. She almost looked like she halfway fell asleep while sitting there so I picked her up and put her on a nice comfy blanket and pet her for a while. (She was purring)

I'll continue to update this thread tomorrow. Need to sleep, been a hellish day.