Oh yes. At least Spooky has. Mulder is kind of... slow.
If Mulder wants something, he just jumps on my lap and headbutts my face or whatever I'm working on until I attend to him. He's a big cat, hard to ignore. Sometimes if he is very persistent I have to lock him out of wherever I am if what I'm doing is important.
What Spooky does depends on the situation.
If I am trying to go to sleep he will knock things off the nightstand/dresser/bathroom counter, attack cords, run around meowing, walk on my body, paw at the window shade (obnoxious noise) and sometimes he swings the door shut which is startling and usually gets my attention.
If I am actually sleeping and he wants me to wake up he will sit on the nightstand and paw at my pillow next to my face until I move or react, then meow at me. If I ignore him, he gets on the pillow and paws my face directly. Not scratching. If I continue to ignore him, he will go walk all over DH until DH tells me to deal with my cat.
If I am awake and not doing what he wants, he starts meowing and knocking things over. He really likes cups with liquids in them. He just walks over to them and swats them over and watches me run for a towel. We use lidded cups here now. Failing cup availability, he will knock over anything on a table - mail, books, pens, etc., get into cords or he will play bite my feet.
Spooky always seems to know what action is required in what situation to really push that "button"!