I was diagnosed with osteopaenia (precursor to osteoporosis) two years ago. My doctor started me on Fosamax. I took it once a week for about a month or so. Within the first week, I started having bad chest pains and tightening in my chest. And my jaw started to ache badly. It got so terrible that I ended up in the ER one night with suspicions of a heart attack. Keep in mind that this whole time, I was walking 5 miles a day and exercising.
After a lot of tests, including two different kinds of stress tests, the doctor said that the heart attack symptoms and the intense jaw pain were due to Fosamax. He had found it difficult to believe that it was heart-related, simply because I was exercising regularly and because I was 54 at the time....although women of any age or shape can have heart attacks.
He told me during the stress test that the most common things with Fosamax are heart attack symptoms. And jaw pain. And sometimes joint issues, too. My own doctor had told me that, so I rather figured it was due to the drug. Anyway, I quit taking it; it wasn't worth all the hassles. And I would never advise anybody to try it....nasty stuff. To this day, I still have jaw pain issues and my dentist says it's from the drug.
OTOH, my MIL has been taking Fosamax for over 10 years with absolutely no trouble.
I take 1200 mg of calcium, 2000 IU of Vit D-3 (to help with the calcium absorption), and 250 mg of magnesium (calcium can cause constipation and did with me....the magnesium helps with the constipation) every day. While the osteopaenia hasn't gotten any better in those two years, it hasn't gotten any worse either.
Weight-bearing exercise is the best thing you can do for osteopaenia.
As for cholesterol issues, if it's not genetic, you can adjust your diet. Lower your calories and eat lots of the dark orange and green veggies. Instead of white potatoes, eat sweets or yams. Broccoli, kale, spinach, etc. Skim milk, egg whites instead of whole eggs. Lots of high-fiber foods and whole wheat foods. More grains, less starch. Prepare your own foods. Stay away from eating a lot of meat....chicken, turkey or pork is far better than beef, as long as you trim the fat. Cut back on fats and use olive oil. Meatless meals once or twice a week. And exercise....simple walking is great for those with high cholesterol. DH has high cholesterol and it's an ongoing struggle for him. He didn't want to take any statins, so his doctor talked with me about changing his diet. It has dropped from a high of 242 to right around 202...and his doctor says it's mostly from changing his diet. We can't seem to drop it any lower than that, unfortunately. And it really is a struggle for him as he's a sweets hound; he loves cakes and cookies.