I was hoping to get some advice for my Brother. He has a girl and a boy named Emmy and Isaac that are 2 year old litter mates. They have always been extremely attached and very loving towards each other. My brother has just recently moved to a new house and his two cats have had some understandable issues adjusting. It has been a few days and Emmy is now walking around pretty content, but Isaac is still very timid and scared of his new surroundings. On top of being scared of his new surroundings he suddenly does not want to be anywhere near his sister. He basically hides in the basement and if she comes down he hisses at her and chases her upstairs. We got a comfort zone diffuser to put in the basement to hopefully calm him down a bit, but I'm not sure if there is anything else we should do. I feel horrible that this move seems to have turned these two little kitties against each other.