anyone know anything about this?
post #1 of 63
9/27/09 at 6:14pm
|Red Cell Count - 5.23
Haemoglobin - 85
HCT - 0.26
MCV - 50
MCH - 16.0
MCHC - 327
White Cell Count - 21.7
Neutrophils - 9.8
Band Forms - 0.0
Lymphocytes - 11.7
Monocytes - 0.2
Plasma Protein - 70
veterinary film review:
- anaemia, anisocytosis +/-. immature erythrocytes including polychromatophilic and basophilic rubricytes, prorubricyte, and fewer rubriblasts and metarubricytes. No polychromasia.
- occassional band and metamyelocytes present, rare promyelocyte
- predominantly small and well differentiated with occasional medium-sized lymphocytes
There are numerous medium to large blasts with a single often centrically located, perfectly round nucleus 2.5 RBC's in diameter, etched chromatin and medium-sized nucleoli. They have deeply basophilic cytoplasm and occassionally contain a clear Golgi zone. Their features are most consistent erythroblasts, but I'm reluctant to completely rule out the possibilty of lymphoblasts.
There is a prominent evidence of apoptosis (programed cell death) and many basket cells (smudged nuclear remnants). A few mitotic figures and a binculeate erythrocyte are observed. Occassional cytoplasimic droplets.
In the absence of polychromasia and no current explanation for the high numbers of immature red blood cells, there is a moderate possiblity that this patient could in the early states of MDS-Er (myelodysplastic syndrome - erythroid predominance or very early Erythroleukaemia (recelently classified as AML M6)
These patients are usually anaemic and this cat is currently not therefore it is very important that other differential causes should also be explored.
If they are ruled out and the haematological findings are persistent then bone marrow cytology is advisable
If this does indeed develop into MDS-Er or AML M6, these patients often have underlying FeLV infection.
Additionally, as with all myeloproliferative diseases in cats pathology involiving one cell line, erythroid in this case, may evolve over months to dysplasisa or neoplasia of another has Erythroleukaemia (recently classified as AML M6)
Is he amemic and has Feline Leuk? Which by reading what you wrote is his white blood cells are eating at the clean red blood cells as they are trying to produce cells to better your kitty. You will hope that his bone marrow will regenerate and produce necessary cells. My fingers are XX'ed for you.
|there is a moderate possiblity that this patient could in the early states of MDS-Er (myelodysplastic syndrome - erythroid predominance or very early Erythroleukaemia (recelently classified as AML M6)|
|feline leukemia complexthe array of diseases associated with infection of cats by the feline leukemia virus; includes lymphoreticular neoplasms, myelodysplastic disorders and abnormalities of the immune system.|
oh Dan, I'm so sorry sweet Cedar is so ill
My cats, who are all FeLV+, sometimes develop a disease where their bone marrow stops producing red blood cells. I cannot for the life of me remember what it is called I know that in these cases, transfusions can help prolong their life, but there is no cure save a bone marrow transplant and, well, you can imagine how difficult that would be to a) find a donor and b) to put the kitty thru that.
You and Cedar are in my thoughts