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Antibiotic Question

post #1 of 23
Thread Starter 
My cat Patch has some kind of a staph infection. He is being treated with Baytril 1/2 tablet once a day 68 mg. tablet. He is not a good pill taker and I have always had to mash up pills. He takes Atenonal for his heart plus an 1/4 aspirin once every third day. My question is now that he has to take this Baytril for 6 weeks. Its too big to mix he is detecting it. I was wondering if I could split the 1/2 pill and give him 1/4 in the morning and 1/4 at night. Would it still be as affective for him. I'd appreciate any advice you can give me. Thanks.
post #2 of 23
My Coco takes Baytril everydayand it is not a good idea to give less then the vet said.
Twice a day at 1/2 the dose is not a good idea.
You can have them compounded into a liquid though.
I did that with Coco's bp meds.
post #3 of 23
Thread Starter 
We tried liquid and it kept separating from the food. He is so tough to give medicine to. He's not a big eater to begin with.
post #4 of 23
Quote:
Originally Posted by aswient View Post
...He is being treated with Baytril 1/2 tablet once a day 68 mg. tablet...
aswient- First, I'm scratching my head here...Bayrtil tablets are only available in three strengths: 15mg, 50mg and 150mg.

Where is your number of 68 coming from?
post #5 of 23
Thread Starter 
Quote:
Originally Posted by BLAISE View Post
aswient- First, I'm scratching my head here...Bayrtil tablets are only available in three strengths: 15mg, 50mg and 150mg.

Where is your number of 68 coming from?
Thats what's on the lablel of the medicine bottle.
post #6 of 23
I'm not sure how big the pill is, but would those pill pockets work?

Sorry, I don't know the answer to your question....I could be very wrong in saying this, and suggest you call your vet but: I would think that you could 1/2 the pill...He's still getting the full dose, just at intervals (my thoughts are based on how we humans take antibiotics, most times it 2 or 3 a day) as long as it is a pill that can be cut in half.... some can't.
post #7 of 23
Thread Starter 
Quote:
Originally Posted by Snake_Lady View Post
I'm not sure how big the pill is, but would those pill pockets work?

Sorry, I don't know the answer to your question....I could be very wrong in saying this, and suggest you call your vet but: I would think that you could 1/2 the pill...He's still getting the full dose, just at intervals (my thoughts are based on how we humans take antibiotics, most times it 2 or 3 a day) as long as it is a pill that can be cut in half.... some can't.
Thats my problem with my boy. You would think pill pockets would be good, but Patch, believe it or not, is such a little timid eater. For a big cat he licks his food very daintily, little tiny licks. Thats how he can detect anything. Thanks for the advice though.
post #8 of 23
I just looked at Coco's Baytril pills and hers say Baytril Taste Tabs 22.7MG(500)
I used to use pill pockets with Coco until she bit into a Baytril Pill last summer.
Can you try dropping the pill as far back as you can get it?
I do that with Coco and it works most of the time.
post #9 of 23
Thread Starter 
Quote:
Originally Posted by mews2much View Post
I just looked at Coco's Baytril pills and hers say Baytril Taste Tabs 22.7MG(500)
I used to use pill pockets with Coco until she bit into a Baytril Pill last summer.
Can you try dropping the pill as far back as you can get it?
I do that with Coco and it works most of the time.
Thats another problem with Patch, he was feral when I took him in at 4 months old and in the 5 years that I have him, he only lets me get as close as HE wants me to be. He's a tough case. Thanks for the advice though.
post #10 of 23
Thread Starter 
Quote:
Originally Posted by mews2much View Post
I just looked at Coco's Baytril pills and hers say Baytril Taste Tabs 22.7MG(500)
I used to use pill pockets with Coco until she bit into a Baytril Pill last summer.
Can you try dropping the pill as far back as you can get it?
I do that with Coco and it works most of the time.
They must come in different mgs because Coco gets 22.7 mg. and 22.7 mg x 3 is 68 mg. that Patch needs.
post #11 of 23
That does make it harder.
post #12 of 23
In that case, I would call your vet and find out if you can split the pill in half and give it to him 2x day, in your usual manner
post #13 of 23
I agree calling the vet would be the easiest.
post #14 of 23
aswient-
So far as your original quetion goes, the manufacturer's dosing regimen allows for either single or twice-daily administration:
Quote:
The dose of Baytril® (brand of enrofloxacin) Tablets in cats is 5 mg/kg (2.27 mg/lb) of body weight, either as a single dose or divided into two (2) equal daily doses administered at twelve (12) hour intervals. In rare instances, use of this product in cats has been associated with retinal toxicity. Based on post approval experience, cats should be carefully monitored for clinical signs of mydriasis and/or changes in the retina. http://www.drugs.com/vet/baytril-tab...50-mg-can.html
BUT, best that you check in with the Vet.

There is an issue that you should be aware of, however. In the middle of that quote above was this tidbit:
Quote:
In rare instances, use of this product in cats has been associated with retinal toxicity.
Translation: Blindness
This article goes into detail about that and there's more info here.
You need to ensure that Patch isn't getting more than 5mg per kg (2.2 pounds) of body weight per day. IF the tablets you have are 68mg, Patch should weigh at least 29.9 pounds. If he weighs less than that, he's getting too much of the drug.

I know you just said he's a large cat but, I wonder if he's that heavy. This is why I started out questioning the strength of the tablets you were given.

I'll PM you a reference where a Vet gets into a lot of detail about all this.
post #15 of 23
Thread Starter 
Quote:
Originally Posted by BLAISE View Post
aswient-
So far as your original quetion goes, the manufacturer's dosing regimen allows for either single or twice-daily administration:
BUT, best that you check in with the Vet.

There is an issue that you should be aware of, however. In the middle of that quote above was this tidbit:Translation: Blindness
This article goes into detail about that and there's more info here.
You need to ensure that Patch isn't getting more than 5mg per kg (2.2 pounds) of body weight per day. IF the tablets you have are 68mg, Patch should weigh at least 29.9 pounds. If he weighs less than that, he's getting too much of the drug.

I know you just said he's a large cat but, I wonder if he's that heavy. This is why I started out questioning the strength of the tablets you were given.

I'll PM you a reference where a Vet gets into a lot of detail about all this.
No he's not that heavy he's 18 lbs. I will have to call the Vet about this new information, Thank you very much.
post #16 of 23
Quote:
Originally Posted by aswient View Post
No he's not that heavy he's 18 lbs...
So, by my math...

18 pounds divided by 2.2 pounds = 8.18 x 5mg/day = 40.9 mg/day Patch's maximum recommended dosage

The original prescribed dosage of 68mg/day works out to 1 2/3 of the maximum.
post #17 of 23
Quote:
Originally Posted by BLAISE View Post
aswient- First, I'm scratching my head here...Bayrtil tablets are only available in three strengths: 15mg, 50mg and 150mg.

Where is your number of 68 coming from?
That is incorrect. Baytril is available in 22.7mg, 68mg, and 136mg if I'm not mistaken. I'm certain about the 22.7mg and the 68mg however.....

68mg does seem like a high dose though. Usually cats are prescribed one 22.7mg tablet once daily. *shrugs* I'd double check with your vet, just to be on the safe side.

As far as getting pills down him, have you tried giving it in tuna? Also, I've heard peanut butter or even butter helps with stubborn babies. Not sure how healthy that is for felines though....
post #18 of 23
Quote:
Originally Posted by CatNurse22 View Post
Quote:
Originally Posted by BLAISE View Post
aswient- First, I'm scratching my head here...Bayrtil tablets are only available in three strengths: 15mg, 50mg and 150mg.

Where is your number of 68 coming from?
That is incorrect. Baytril is available in 22.7mg, 68mg, and 136mg if I'm not mistaken. I'm certain about the 22.7mg and the 68mg however.....

68mg does seem like a high dose though. Usually cats are prescribed one 22.7mg tablet once daily...I'd double check with your vet, just to be on the safe side.....
Actually, CatNurse22, Baytril is indeed available in the strengths I indicated - in Canada - you'll find the individual references here.

In the US, the available strengths are as you indicated.

I was only familiar with the Canadian availability.

Now, your statement that "Usually cats are prescribed one 22.7mg tablet once daily" is patently incorrect. Baytril is one antibiotic that MUST be dosed according to the weight of the cat (or dog) - unlike, e.g., Clavamox, where the dosage for a cat is one 62.5mg tablet twice daily.
post #19 of 23
Quote:
Originally Posted by CatNurse22 View Post
That is incorrect. Baytril is available in 22.7mg, 68mg, and 136mg if I'm not mistaken. I'm certain about the 22.7mg and the 68mg however.....

68mg does seem like a high dose though. Usually cats are prescribed one 22.7mg tablet once daily. *shrugs* I'd double check with your vet, just to be on the safe side.

As far as getting pills down him, have you tried giving it in tuna? Also, I've heard peanut butter or even butter helps with stubborn babies. Not sure how healthy that is for felines though....
Quote:
Originally Posted by BLAISE View Post
Actually, CatNurse22, Baytril is indeed available in the strengths I indicated - in Canada - you'll find the individual references here.

In the US, the available strengths are as you indicated.

I was only familiar with the Canadian availability.

Now, your statement that "Usually cats are prescribed one 22.7mg tablet once daily" is patently incorrect. Baytril is one antibiotic that MUST be dosed according to the weight of the cat (or dog) - unlike, e.g., Clavamox, where the dosage for a cat is one 62.5mg tablet twice daily.
This is a perfect example of why it is dangerous to give or receive medical information via internet. Because there are many countries on this site, we must be very careful what we post about medically.

To the OP - if you have questions regarding the medication or dosages you are giving your cat, your vet or a second opinion from another vet is the way to go. We have no vets on this site and even if we did, nobody can diagnose your animal over the internet. We can share experiences and strongly suggest you discuss what you learn from those shared experiences with your own vet.
post #20 of 23
Quote:
Originally Posted by BLAISE View Post
Actually, CatNurse22, Baytril is indeed available in the strengths I indicated - in Canada - you'll find the individual references here.

In the US, the available strengths are as you indicated.

I was only familiar with the Canadian availability.

Now, your statement that "Usually cats are prescribed one 22.7mg tablet once daily" is patently incorrect. Baytril is one antibiotic that MUST be dosed according to the weight of the cat (or dog) - unlike, e.g., Clavamox, where the dosage for a cat is one 62.5mg tablet twice daily.
Thus suggesting the use of usually.... Yes, it is by weight. Cats (at least compared to dogs) are usually in the same weight range. And no vet is going to 1/8 or 1/16 a tablet because it's a few tenths of a mg off (or even a mg or two) for the recommended dosage for a certain weight.

Let's not turn this into a debate about something that is ultimately completely off topic of the OP.
post #21 of 23
Thread Starter 
Well Patch does need the mgs. he was prescribed, he has a pretty good staph infection. I called the Vet and they said its best not to break the pill so he gets it spaced out. My problem is he is still evading the pill. No matter what I crush it up in. I guess its because the mg is so high that the pill is bigger and harder to hide. I'm at my wits end with this boy. Thanks for all your advice everyone. My Patch is a tough case.
post #22 of 23
Quote:
Originally Posted by CatNurse22 View Post
...no vet is going to 1/8 or 1/16 a tablet because it's a few tenths of a mg off (or even a mg or two) for the recommended dosage for a certain weight...
CatNurse, this is not a question of a milligram or two...the prescribed dosage is almost DOUBLE the MAXIMUM RECOMMENDED BY THE MANUFACTURER AND FDA. And...
Quote:
Higher doses (>5 mg/kg/day) not recommended in cats; may cause blindness" -Plumb's Veterinary Drug Handbook Fifth edition.
Quote:
Originally Posted by aswient View Post
...Patch does need the mgs. he was prescribed, he has a pretty good staph infection. I called the Vet and they said its best not to break the pill so he gets it spaced out...
This "not breaking the pill part" is particularly difficult to understand. This is not a timed-release tablet. From Drugs.com:
Quote:
Concentrations of drug equal to or greater than the MIC for many pathogens (See Tables I, II and III) are reached in most tissues by two hours after dosing at 2.5 mg/kg and are maintained for 8-12 hours after dosing.
Obviously then, dosing only once a day will mean an "uneven" concentration of the drug in the system with a peak early in the first 12 hours after dosing followed by an inefficient amount of available drug later in the following 12 hours. A more consistent level of drug availability over a 24 hour period would be achieved by an equal dosage every 12 hours.

That would be my "take" on this - I know I would seek a second opinion if Patch were mine.

aswient- Do you know whether/not the Vet did a culture to determine which bacteria is at play?
post #23 of 23
aswient - as I said in my earlier post, if you are questioning your vet's recommendation, then please consult another vet for a second opinion. All we can do at this site is quote you information from the internet and that is not always reliable. It really is best to consult another vet if you doubt the first vet's opinion.

Vet's are good and bad but they still have more medical knowledge than we do here.
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