After the Depo-Medrol shot Bugsy got all quiet, doesn't want to play with Lucky anymore... He used to love playing chase and hide and seek, but no more... I did the research, and it is a normal side effect in some cats. I see that he is improving everyday, his energy is coming back, but so slowly! I can't wait until the shot is completely out of his system! I will not give this shot to him again - will definitely seek other options for his gingivitis! Sorry - just needed to vent - I am frustrated, and want my playful lover bug back!