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Buprenex question

post #1 of 16
1/18/09 at 5:40pm
Thread Starter 
How long do buprenex filled syringes last? Do they last longer in the fridge?
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post #2 of 16
1/18/09 at 5:44pm
They last at least a year.
I have some from Nov 2007 and they were good until Jan 3rd 2009
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post #3 of 16
1/18/09 at 6:39pm
Thread Starter 
really, my vet said 3 weeks - but I really doubted that because that seems like a really short shelf life for a vet......there's no expiration date on the syringes.
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post #4 of 16
1/18/09 at 6:49pm
Mine has a date on the bag.
There are 5 syringes and in the bag.
The vet has a label on it with the date it expires.
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post #5 of 16
1/18/09 at 6:52pm
Do you want me to take a picture of the bag so i can show you what they look like.
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post #6 of 16
1/18/09 at 6:54pm
I found this online:

Quote:
6.3\tShelf life

Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.
The product does not contain an antimicrobial preservative. Use immediately after opening the ampoule. Any solution remaining in an ampoule following withdrawal of the required dose should be discarded
Site:
http://www.vmd.gov.uk/espcsite/Documents/206474.DOC

So I imagine out of the bottle 3 weeks is probably a good estimate considering the syringes are not air tight.
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post #7 of 16
1/18/09 at 6:56pm
Thread Starter 
ah, now that makes sense....do you think that it would make a difference keeping it in the fridge?
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post #8 of 16
1/18/09 at 7:02pm
Hmmm I'm not sure.

I mean technically everything lasts longer in the fridge right? I'm sure it can't hurt anything.
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post #9 of 16
1/18/09 at 7:18pm
This is Cocos medicine with the due date on it.




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post #10 of 16
1/18/09 at 7:24pm
My only question with your meds though is is that the expiration date of the medication put into the syringes or the expiration cate on the bottle it was taken out from?

It's kind of like compounding meds... when you crush the tab up if you don't have a certain preservative it only lasts so long.

I'm gonna have to ask what our policy is when I go to work tuesday because now I'm really curious if it has a shelf life or not in the syringe!
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post #11 of 16
1/18/09 at 7:29pm
Now you have me wondering.
My Meeko is having surgery tomorrow and they said she will getthe same med.
The syringes in the picture are Cocos.
I wonder if it should have been in the fridge.
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post #12 of 16
1/18/09 at 7:32pm
I can't help...Larissa's is in a small container and I'm drawing up her dose each time it's due...it's just enough for the couple of days before her surgery and possible biopsy.
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post #13 of 16
1/18/09 at 7:34pm
I'm pretty sure though when we send it home you don't have to refrigerate it. I mean the bottle itself doesn't even get refrigerated...

Online I found something that says if it has been diluted it has a 30 day shelf life. But the stuff in the bottle should be pure medication, not diluted I assume.

http://www.elephantcare.org/Drugs/buprenor.htm
That website says for storage:
Quote:
Storage/Stability/Compatibility - Buprenorphine should be stored at room temperature (15-30° C). Temperatures above 40° C or below freezing should be avoided. Buprenorphine products should be stored away from bright light. Autoclaving may decrease drug potency considerably. The drug is stable between a pH of 3.5-5.
Which is kind of odd as well because they come in clear vials when they arrive... although I guess they are in boxes. Wow I'm gonna have to read up on this. I keep googling things but almost everything is for humans because it's apparently used for people who are addicted to narcotics.
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post #14 of 16
1/19/09 at 2:48am
Thread Starter 
Well I'm glad I'm not the only one questioning this. Sounds to me like there's a few of us that could really benefit from this information.
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post #15 of 16
1/19/09 at 8:13am
I just took Meeko to the vet for her surgery and I asked.
They said the date on the bottle is how long its good for.
They also said it does not need to go in the fridge.
Meeko will be getting some when she comes home.
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post #16 of 16
5/18/10 at 4:04pm
Just wanted to add that I asked our pharmacist and he stated that the shelf life for his unopened vial of Buprenex is 3 years. He said a rule of thumb for it was once he opened the vial it would cut that in half.

He said that after that date the potency would diminish.
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