I have 4 cats with a possibility of keeping the stray I just rescued and need some advice. I love reading everyone's suggestions and have learned alot. It does seem that everyone here with a multi-cat household experiences some difficulties with cats getting along all of the time. I also have living with me 3 young cats, 2 littermates and another around the same age. I keep them separate from my cats as my daughter will take them with her when she gets married in September. I fostered them and they all get along great!! My other daughters have multi cat households-2 in one home and 3 in another- again all get along-no problems at all. Of my 4 cats, the oldest female can be the sweetest cat in the world-but there are times when she can just be so nasty. She does tolerate 2 of the others, every once in a while she may hiss or just growl, but I have a rescued feral and there are times she just goes after her. Sometimes they lay in the same room and everything is fine, then for no apparent reason, she will just try to attack her. I tried the Feliway comfort plug-in and although I have heard it is great, I swear it made her worse. Right now I am trying SpiritEssences with little or no change. I just actually had to take my feral to the vet, which was an experience, because she had an infection on her back that may have been caused by a bite from my cat. I am so upset, I also just rescued another stray who is still in isolation and since shelters here are so full, I would love to keep him and give him a home. I would love for all to get along, do you think that maybe I should just isolate the aggressive one from the others? Right now she is sitting on my lap purring and so sweet, it sounds crazy but it is almost as if she is jealous because of all of the time I have spent working with the feral. This poor feral had such a bad start to her life, I am committed to her having the best life from now on. I do keep her in her own room during the night so I have peace of mind that she is not being tormented. Any advice or help would be appreciated.