Yes I know about breed specific health problems and some breeds/ages being more sensitive to anesthesia. But you asked about vaccines. There aren't too many options on ways to give a vaccine. I don't really care much for Intranasal vaccines anyways. Kittens get vaccinated around 6 weeks and continue every 3 or so weeks until 16 weeks.Then it is up to you if you want to vaccinate yearly, every 3 years, or never again. I vaccinate again after 3 years and then never again. I think yearly vaccines are horrible but that is personal opinion and common sense, not breed related.