Then I would venture a guess that what you have is cystic acne.http://www.acne.org/types-of-acne.html
The cortisone is going to work best for you if this is the case.
If you are troubled by it, there are amazing products only avalible by perscription, a good Dermatologist can set up a program for you.
A few suggestions, if you are using a fabric softner sheet, the kind you use in the dryer, stop, and get a liquid ball dispenser, you can find them anywhere and Downy makes one.http://www.downy.com/en_US/products/ball.jsp
Use only white pillow cases, do not use harsh acne products that you can buy in a drug store, they only use drying agents, and that makes the issue worse. Try Dove soap or cetaphil. Avoid any "clear" bar soaps and glycerin based products as well.
Try not to pick