When we got Neffie she was living in a basment and hated all humans. Just wouldn't let anyone get close to her, not to touch her, pet her , pick her up, nothing. She lived like this for 7 years and so now that she's out of that situation and living with us, we find daily that she has quirks, like wanting to be queen of the roost,(which doesn't sit well with the current king, Twig) She is very finicky about who can come near her and how close they can get too. She will let DH and I get close enough to pet her but not at the same time, and she will rub on our legs for pettings. She likes to play with a red string and her mouse mouse. ALL the time 24/7 if she had her way. But the biggest thing we can't figure out is we try to pick her up and she FREAKS out! She crys, squirms and does everything in her power to get away from being in your grasp, then when she's back on the floor she gives you the dirtiest look and walks away.
So we have tried something that reinforces that we aren't going to hurt her and that her being picked up isn't a bad thing. We pick her up, let her go when she gets upset but when she gets down we give her treats so she knows she's a good girl for letting us pick her up. She's doing ok now, she still hates to be picked up but isn't freaking out everytime now, just about 90% of the time.(which for her is very good)
SO maybe you could try this with your kitty, it might work, it might not. Or I could be giving you the completely wrong advice. I'm just telling you what seems to be helping us with our 7 year old addition.
Good luck with her.